IONIS PHARMACEUTICALS INC (IONS) Stock Technical Analysis

NASDAQ:IONS • US4622221004

80.93 USD
-4.52 (-5.29%)
At close: Feb 25, 2026
80.5 USD
-0.43 (-0.53%)
After Hours: 2/25/2026, 8:21:36 PM
Technical Rating and Analysis

7

We assign a technical rating of 7 out of 10 to IONS. In the last year, IONS was one of the better performers, but we do observe some doubts in the very recent evolution.

  • The short term is neutral, but the long term trend is still positive. Not much to worry about for now.
  • When comparing the yearly performance of all stocks, we notice that IONS is one of the better performing stocks in the market, outperforming 94% of all stocks.
  • IONS is part of the Biotechnology industry. There are 521 other stocks in this industry. IONS outperforms 83% of them.
  • IONS is currently trading near its 52 week high, which is a good sign. The S&P500 Index however is also trading near new highs, which makes the performance in line with the market.
  • IONS has an average volume of 2075170 traded shares per day. This is a good sign as it is always nice to have a liquid stock.
  • In the last month IONS has a been trading in the 79.78 - 86.74 range, which is quite wide. It is currently trading in the middle of this range, so some resistance may be found above.
Weekly and Daily overview Charts
IONIS PHARMACEUTICALS INC / IONS Weekly stock chart
IONIS PHARMACEUTICALS INC / IONS Daily stock chart
Setup Rating and Analysis

6

Besides having an excellent technical rating, IONS also presents a decent setup pattern. Prices have been consolidating lately. There is a support zone below the current price at 77.08, a Stop Loss order could be placed below this zone. Very recently a Pocket Pivot signal was observed. This is another positive sign.

  • A Pocket Pivot is a price/volume accumulation pattern. A Pocket Pivot occurs when price moves up with volume higher than the maximum down volume registered in the previous 10 days.
Support and Resistance Analysis

64.43

87.37

2 important support areas can be observed.

  • A support zone ranging from 76.33 to 77.08. This zone is formed by a combination of multiple trend lines in multiple time frames.
  • Support @65.08 from a trend line in the weekly time frame.

2 important resistance areas can be observed.

  • A resistance zone ranging from 81.19 to 81.23. This zone is formed by a combination of multiple trend lines and important moving averages in the daily time frame.
  • A resistance zone ranging from 86.50 to 86.50. This zone is formed by a combination of multiple trend lines in multiple time frames.
Technical Indicator Signal Analysis

The Technical Rating and Setup analysis above combine different indicators and trends in different timeframes. Individual signals from indicators may give more contradictive signals and should always be interpreted in the more global context.

IndicatorValueSignalComment
ChartMill Long Term Trend IndicatorUPPOSITIVEThe long term trend for IONS is up.
ChartMill Short Term Trend IndicatorNEUTRALNEUTRALThe short term trend for IONS is neutral.
ChartMill Relative Strength94.21POSITIVEIONS has a high relative strength, it outperformed 94.21% off all stocks on the market.
Simple Moving Average/SMA (20)DOWNNEGATIVEThe current price of IONS is below a declining SMA(20).
Simple Moving Average/SMA (50)UPMIXEDThe current price of IONS is below the rising SMA(50).
Simple Moving Average/SMA (200)UPPOSITIVEThe current price of IONS is above the rising SMA(200).
Relative Strength Index/RSI (14)45.7NEUTRALThe RSI value for IONS is a neutral value.
Moving Average Convergence Divergence/MACD (12, 26, 9)-0.19NEGATIVEThe MACD value suggests IONS has a negative trend.
Stochastics (14,3)55.75NEUTRALThe Stochastics value for IONS is a neutral value.
Average True Range in percent/ATR (20)3.12MEDIUM VOLATILITYThe ATR as a percentage value for IONS suggests some volalility.
Average Directional Index/ADX (14)14.27NEGATIVEThe low ADX value for IONS suggests a weak or negative trend.
Chart- and CandleStick Pattern Analysis
Daily CandleStick Patterns
Bullish Engulfing (D)
Bullish Hammer (D)
Bearish Inverted Hammer (D)
Hanging Man (D)
Bullish Harami (D)
Doji (D)
Gravestone Doji (D)
DragonFly Doji (D)
Bearish Engulfing (D)
Bearish Shooting Star (D)
Bearish Harami (D)
Inside Bar (D)
Red Dog Reversal Down (D)
Red Dog Reversal Up (D)
Dark Cloud Cover (D)
Weekly CandleStick Patterns
Bullish Engulfing (W)
Bullish Hammer (W)
Bearish Inverted Hammer (W)
Hanging Man (W)
Bullish Harami (W)
Doji (W)
Gravestone Doji (W)
DragonFly Doji (W)
Bearish Engulfing (W)
Bearish Shooting Star (W)
Bearish Harami (W)
Inside Bar (W)
Dark Cloud Cover (W)
Daily Chart Patterns
Bull Flag
Bear Flag
Ascending Triangle (D)
Descending Triangle (D)
Symmetrical Triangle (D)
Squeeze
Channel (D)
Channel Up (D)
Channel Down (D)
Rising Wedge (D)
Falling Wedge (D)
Double Bottom (D)
Multiple Bottom (D)
Double Top (D)
Multiple Top (D)
Weekly Chart Patterns
Weekly Bull Flag
Weekly Bear Flag
Squeeze Week
Channel (W)
Double Bottom (W)
Multiple Bottom (W)
Double Top (W)
Multiple Top (W)
Example Setup

Important!: this is just an example which is fully automatically generated based on the analysis above and should in no way be interpreted as a suggestion. Always make your own analysis and determine your own entry and exit points.

ENTRYEXITDISTANCECAPITAL
81.2479.771.47 (1.81%)25.00%
An entry @81.24. This is a Buy Stop order right above the resistance zone.An exit @79.77. This is a Stop Loss order right below the 10 day low.The worst case loss on the trade is limited to 1.47 points, which is 1.81%.For a 0.45% total portfolio risk, you can invest 25.00% of your capital in this trade.

  • The distance between exit and entry is rather small compared to the average daily movement of IONS. Please evaluate whether better entry and exit points can be found.
  • The generated setup is based on the nearest support and resistance areas. If you are looking for a more long term trade, probably a wider stop is advisable.
  • This trade setup was generated fully automatically and should not be interpreted as trading advice. Always check the related news for upcoming earnings or other events. Make your own analysis and trade at your own responsibility.
IONIS PHARMACEUTICALS INC / IONS Daily stock chart

IONIS PHARMACEUTICALS INC

NASDAQ:IONS (2/25/2026, 8:21:36 PM)

After market: 80.5 -0.43 (-0.53%)

80.93

-4.52 (-5.29%)

Chartmill TA Rating
Chartmill Setup Rating
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
Performance
% Chg-5.29%
1 Week-1.57%
2 Weeks-3.99%
1 Month-1.47%
3 Month-2.18%
6 Month89.82%
12 Month143.84%
2 Year79.01%
3 Year125.43%
5 Year54.45%
10 Year134.17%
15 YearN/A
Volatility
ATR(14)2.72
ATR(20)%3.12%
ATR Inc32.6%
Range Today4.64
ADR(20)2.46
ADR(20)%3.04%
Trend & SMA
ST Trend
LT Trend
SMA(5)
SMA(10)
SMA(20)
SMA(50)
SMA(100)
SMA(200)
Relative Strength & Ranges
CRS94.21
3 months CRS32.21
6 months CRS96.31
Mansfield3.56
10 Day High85.47
10 Day Low79.78
20 Day High86.74
20 Day Low79.78
52 Week High86.74
52 Week Low23.95
CS1 End77.08
CR1 Start81.19
Volume & EV
DER(3)1.5%
DER(5)1.7%
Volume3.19M
Volume Incr16.52%
Vol(5)2.43M
Vol(50)2.08M

IONIS PHARMACEUTICALS INC / IONS FAQ

What is the technical rating for IONS stock?

ChartMill assigns a technical rating of 7 / 10 to IONS.


What is the current trend direction of IONIS PHARMACEUTICALS INC (IONS) stock?

The current trend direction for IONIS PHARMACEUTICALS INC (IONS) is Bullish.


What is the RSI signal for IONS stock?

IONIS PHARMACEUTICALS INC (IONS) has an RSI value of 45.7001. This indicates that the stock is currently neutral.


What is the short term momentum for IONIS PHARMACEUTICALS INC (IONS) stock?

The short term momentum for IONIS PHARMACEUTICALS INC (IONS) is neutral.