IONIS PHARMACEUTICALS INC (IONS) Stock Price & Overview

NASDAQ:IONS • US4622221004

74.79 USD
-0.87 (-1.15%)
At close: Mar 11, 2026
74.75 USD
-0.04 (-0.05%)
After Hours: 3/11/2026, 6:07:38 PM

The current stock price of IONS is 74.79 USD. Today IONS is down by -1.15%. In the past month the price decreased by -11.27%. In the past year, price increased by 126.91%.

IONS Key Statistics

52-Week Range23.95 - 86.74
Current IONS stock price positioned within its 52-week range.
1-Month Range73.15 - 85.47
Current IONS stock price positioned within its 1-month range.
Market Cap
12.355B
P/E
N/A
Fwd P/E
N/A
EPS (TTM)
-2.44
Dividend Yield
N/A

IONS Stock Performance

Today
-1.15%
1 Week
-5.87%
1 Month
-11.27%
3 Months
-7.46%
Longer-term
6 Months +18.41%
1 Year +126.91%
2 Years +72.53%
3 Years +109.26%
5 Years +66.35%
10 Years +84.67%

IONS Stock Chart

IONIS PHARMACEUTICALS INC / IONS Daily stock chart

IONS Technical Analysis

ChartMill assigns a technical rating of 4 / 10 to IONS. When comparing the yearly performance of all stocks, IONS is one of the better performing stocks in the market, outperforming 93.35% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating
IONS Full Technical Analysis Report

IONS Fundamental Analysis

ChartMill assigns a fundamental rating of 3 / 10 to IONS. IONS has a bad profitability rating. Also its financial health evaluation is rather negative.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend
IONS Full Fundamental Analysis Report

IONS Earnings

On February 25, 2026 IONS reported an EPS of -1.41 and a revenue of 203.00M. The company missed EPS expectations (-4.63% surprise) and beat revenue expectations (27.5% surprise).

Next Earnings DateApr 28, 2026
Last Earnings DateFeb 25, 2026
PeriodQ4 / 2025
EPS Reported-$1.41
Revenue Reported203M
EPS Surprise -4.63%
Revenue Surprise 27.50%
IONS Earnings History

IONS Forecast & Estimates

29 analysts have analysed IONS and the average price target is 92.16 USD. This implies a price increase of 23.23% is expected in the next year compared to the current price of 74.79.

For the next year, analysts expect an EPS growth of -58.89% and a revenue growth -6.89% for IONS


Analysts
Analysts81.38
Price Target92.16 (23.23%)
EPS Next Y-58.89%
Revenue Next Year-6.89%
IONS Forecast & Estimates

IONS Groups

Sector & Classification

IONS Financial Highlights

Over the last trailing twelve months IONS reported a non-GAAP Earnings per Share(EPS) of -2.44. The EPS increased by 19.74% compared to the year before.


Income Statements
Revenue(TTM)943.71M
Net Income(TTM)-381.39M
Industry RankSector Rank
PM (TTM) N/A
ROA -10.82%
ROE -77.98%
Debt/Equity 3.88
Chartmill High Growth Momentum
EPS Q2Q%-113.64%
Sales Q2Q%-10.57%
EPS 1Y (TTM)19.74%
Revenue 1Y (TTM)33.83%
IONS financials

IONS Ownership

Ownership
Inst Owners105.44%
Shares165.19M
Float163.60M
Ins Owners0.82%
Short Float %9.65%
Short Ratio7.2
IONS Ownership

IONS Competitors/Peers

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ABBV ABBVIE INC15.34401.392B
AMGN AMGEN INC16.55202.383B
GILD GILEAD SCIENCES INC16.52184.425B
VRTX VERTEX PHARMACEUTICALS INC25.4126.804B
REGN REGENERON PHARMACEUTICALS16.5781.619B
ALNY ALNYLAM PHARMACEUTICALS INC42.9542.754B
INSM INSMED INC N/A31.007B
NTRA NATERA INC N/A28.197B
BIIB BIOGEN INC11.8527.651B
UTHR UNITED THERAPEUTICS CORP18.2423.485B
MRNA MODERNA INC N/A21.714B
EXAS EXACT SCIENCES CORP340.1819.732B
RVMD REVOLUTION MEDICINES INC N/A19.591B

About IONS

Company Profile

IONS logo image Ionis Pharmaceuticals, Inc. engages in the development and commercialization of human therapeutic drugs using antisense technology. The company is headquartered in Carlsbad, California and currently employs 1,402 full-time employees. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.

Company Info

IPO: 1991-05-17

IONIS PHARMACEUTICALS INC

2855 Gazelle Court

Carlsbad CALIFORNIA 92010 US

CEO: Brett P. MONIA

Employees: 1402

IONS Company Website

IONS Investor Relations

Phone: 17609319200

IONIS PHARMACEUTICALS INC / IONS FAQ

What does IONS do?

Ionis Pharmaceuticals, Inc. engages in the development and commercialization of human therapeutic drugs using antisense technology. The company is headquartered in Carlsbad, California and currently employs 1,402 full-time employees. Its marketed medicines consist of TRYNGOLZA, WAINUA (eplontersen), SPINRAZA (nusinersen), QALSODY (tofersen), TEGSEDI (inotersen) and WAYLIVRA (volanesorsen). TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS). WAINUA is approved for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults. SPINRAZA is used for the treatment of pediatric and adult patients with spinal muscular atrophy. QALSODY is approved for the treatment of Amyotrophic Lateral Sclerosis in adults who have a mutation in the superoxide dismutase 1 (SOD1) gene, or SOD1-ALS. TEGSEDI is approved for the treatment of ATTRv-PN in adults. WAYLIVRA is approved as an adjunct to diet in adult patients with genetically confirmed FCS and at high risk of acute, potentially fatal pancreatitis.


What is the stock price of IONIS PHARMACEUTICALS INC today?

The current stock price of IONS is 74.79 USD. The price decreased by -1.15% in the last trading session.


Does IONS stock pay dividends?

IONS does not pay a dividend.


How is the ChartMill rating for IONIS PHARMACEUTICALS INC?

IONS has a ChartMill Technical rating of 4 out of 10 and a ChartMill Fundamental rating of 3 out of 10.


Where is IONIS PHARMACEUTICALS INC (IONS) stock traded?

IONS stock is listed on the Nasdaq exchange.


What is the expected growth for IONS stock?

The Revenue of IONIS PHARMACEUTICALS INC (IONS) is expected to decline by -6.89% in the next year. Check the estimates tab for more information on the EPS, Sales, EBIT and EBITDA future analyst estimates.