IONIS PHARMACEUTICALS INC (IONS) Forecast, Price Target & Analyst Ratings

NASDAQ:IONS • US4622221004

74.04 USD
-1.12 (-1.49%)
At close: Mar 6, 2026
73.625 USD
-0.42 (-0.56%)
After Hours: 3/6/2026, 8:27:08 PM

View the latest analyst price targets, stock forecast, EPS estimates, revenue projections, revisions, full estimates, rating distribution and upgrades/downgrades for IONIS PHARMACEUTICALS INC (IONS).

Forecast Snapshot

Consensus Price Target

Price Target
$92.16
+ 24.48% Upside

Next Earnings Forecast

Earnings Estimate
Release DateApr 28, 2026
PeriodQ1 / 2026
EPS Estimate-$0.90
Revenue Estimate199.47M

ChartMill Buy Consensus

Rating
81.38%
Weighted Analyst Rating Score

Price Target Details & History

Consensus Price Target and Range

Mean target
$92.16
Upside
+ 24.48%
From current price of $74.04 to mean target of $92.16, Based on 29 analyst forecasts
Low
$46.46
Median
$96.90
High
$115.50

Price Target Revisions

1 Month
2.65%
3 Months
8.11%

Price Target Summary

29 analysts have analysed IONS and the average price target is 92.16 USD. This implies a price increase of 24.48% is expected in the next year compared to the current price of 74.04.
The average price target has been revised upward by 8.11% in the past 3 months.
→ Find peer stocks trading 30% below analyst price target

Analyst Ratings & History

Current Analyst Ratings

IONS Current Analyst RatingIONS Current Analyst Buy, Sell and Hold Ratings.Current Analyst Rating Strong Buy Buy Hold Sell Strong Sell 2 4 6 8 10

Analyst Ratings History

IONS Historical Analyst RatingsIONS Historical Analyst Buy, Sell and Hold Ratings and number of analysts.Historical Monthly Analyst Rating -19 -17 -15 -13 -11 -9 -7 -5 -3 -1 10 20 30

Analyst Ratings Consensus

ChartMill Buy Consensus
81.38%
IONS was analyzed by 29 analysts. The buy percentage consensus is at 81. So analysts seem to be very confident about IONS.
In the previous month the buy percentage consensus was at a similar level.
IONS was analyzed by 29 analysts, which is quite many. So the average rating should be quite meaningful.
→ Find peer stocks with a buy consensus above 85%

Recent Upgrades & Downgrades

DateFirmActionFrom → To
2026-03-03Leerink PartnersMaintains Outperform -> Outperform
2026-02-27Piper SandlerMaintains Overweight -> Overweight
2026-02-26NeedhamMaintains Buy -> Buy
2026-02-26StifelMaintains Hold -> Hold
2026-02-06Piper SandlerMaintains Overweight -> Overweight
2026-01-05Wells FargoMaintains Overweight -> Overweight
2025-12-17RBC CapitalMaintains Outperform -> Outperform
2025-12-15Leerink PartnersMaintains Outperform -> Outperform
2025-12-09B of A SecuritiesMaintains Buy -> Buy
2025-11-10HC Wainwright & Co.Maintains Buy -> Buy
2025-11-04Piper SandlerMaintains Overweight -> Overweight
2025-10-30TD CowenMaintains Buy -> Buy
2025-10-30NeedhamMaintains Buy -> Buy
2025-10-30RBC CapitalMaintains Outperform -> Outperform
2025-10-30BarclaysMaintains Overweight -> Overweight
2025-10-30Raymond JamesReiterate Strong Buy -> Strong Buy
2025-10-30Morgan StanleyMaintains Overweight -> Overweight
2025-10-30HC Wainwright & Co.Maintains Buy -> Buy
2025-10-16Morgan StanleyMaintains Overweight -> Overweight
2025-10-08NeedhamMaintains Buy -> Buy
2025-10-08OppenheimerMaintains Outperform -> Outperform
2025-10-08JP MorganUpgrade Neutral -> Overweight
2025-10-08HC Wainwright & Co.Reiterate Buy -> Buy
2025-10-06StifelMaintains Hold -> Hold
2025-09-26Goldman SachsUpgrade Sell -> Neutral

Next Earnings Forecast Details

Next Earnings Details

Release DateApr 28, 2026
PeriodQ1 / 2026
EPS Estimate-$0.90
Revenue Estimate199.47M
Revenue Q2Q51.11%
EPS Q2Q3.12%
Number of Analysts17

Next Earnings Revisions

Revenue (1 Month)
1.63%
Revenue (3 Months)
4.02%
EPS (1 Month)
-0.82%
EPS (3 Months)
-1.44%

Next Earnings Summary

IONS is expected to report earnings on 4/28/2026. The consensus EPS estimate for the next earnings is -0.9 USD and the consensus revenue estimate is 199.47M USD.
The next earnings revenue estimate has been revised upward by 4.02% in the past 3 months.
→ Find peers expecting at least 20% revenue growth next quarter

Full Analyst Estimates

Yearly Earnings Per Share (EPS), Revenue, EBIT, EBITDA and Operating Margin Analyst Estimates

2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 2033
Revenue
YoY % growth
IONS revenue by date.IONS revenue by date.
787.647M
34.09%
705.138M
-10.48%
943.711M
33.83%
852.6M
-9.65%
1.419B
66.43%
1.892B
33.33%
2.745B
45.08%
3.564B
29.84%
4.3B
20.65%
4.933B
14.72%
5.292B
7.28%
EBITDA
YoY % growth
IONS ebitda by date.IONS ebitda by date.
-320.879M
18.46%
-463.131M
-44.33%
-369.237M
20.27%
-547.674M
-48.33%
-134.015M
75.53%
-411.098M
-206.76%
N/AN/AN/AN/AN/A
EBIT
YoY % growth
IONS ebit by date.IONS ebit by date.
-333.73M
18.64%
-475.081M
-42.35%
-381.684M
19.66%
-519.91M
-36.21%
-246.481M
52.59%
145.89M
159.19%
748.65M
413.16%
1.396B
86.47%
1.892B
35.53%
2.363B
24.89%
2.621B
10.92%
Operating Margin
IONS operating margin by date.IONS operating margin by date.
-42.37%-67.37%-40.45%-60.98%-17.37%7.71%27.27%39.17%44.00%47.90%49.53%
EPS
YoY % growth
IONS eps by date.IONS eps by date.
-2.56
11.42%
-3.04
-18.75%
-2.44
19.74%
-3.88
-58.89%
-1.50
61.35%
0.50
133.13%
4.04
713.28%
6.47
60.37%
8.56
32.18%
9.99
16.72%
10.93
9.39%

All data in USD

Quarterly Earnings Per Share (EPS), Revenue, EBIT and EBITDA Analyst Estimates

Q1 / 26 Q2 / 26 Q3 / 26 Q4 / 26 Q1 / 27 Q2 / 27 Q3 / 27 Q4 / 27
EPS
Q2Q % growth
-0.90
3.12%
-1.02
-245.96%
-0.69
14.06%
-0.65
53.70%
-0.98
-8.68%
-0.83
19.14%
-0.60
12.46%
-0.44
32.81%
Revenue
Q2Q % growth
199.47M
51.11%
194.2M
-57.04%
232.52M
48.10%
242.97M
19.69%
210.89M
5.73%
242.96M
25.11%
285.74M
22.89%
318.28M
31.00%
EBITDA
Q2Q % growth
-138.113M
4.12%
-175.732M
-220.79%
-131.931M
12.99%
N/AN/AN/AN/AN/A
EBIT
Q2Q % growth
-151.15M
-2.92%
-171.414M
-222.60%
-123.384M
22.97%
-121.019M
43.57%
N/AN/AN/AN/A

All data in USD

Yearly Earnings Per Share (EPS) and Revenue Trends vs Historical Data

IONS Yearly Revenue VS EstimatesIONS Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2015 2017 2019 2021 2023 2025 2027 2029 2031 2033 1B 2B 3B 4B 5B
IONS Yearly EPS VS EstimatesIONS Yearly EPS VS EstimatesYearly EPS VS Estimates 2015 2017 2019 2021 2023 2025 2027 2029 2031 2033 0 5 10

Long Term Forward Growth Forecast Summary

Long Term EPS Growth (CAGR)

EPS Next 3 Year
14.92%
EPS Next 5 Year
27.59%

Long Term Revenue Growth (CAGR)

Revenue Next 3 Year
29.93%
Revenue Next 5 Year
32.80%

Long Term EBIT Growth (CAGR)

EBIT Next 3 Year
21.55%
EBIT Next 5 Year
N/A
→ Find peers expecting at least 20% CAGR revenue growth over the next 3 years

IONIS PHARMACEUTICALS INC / IONS Forecast FAQ

What is the price target for IONS stock?

29 analysts have analysed IONS and the average price target is 92.16 USD. This implies a price increase of 24.48% is expected in the next year compared to the current price of 74.04.


When does IONIS PHARMACEUTICALS INC (IONS) report earnings?

IONIS PHARMACEUTICALS INC (IONS) will report earnings on 2026-04-28.


What are the consensus estimates for IONS stock next earnings?

The consensus EPS estimate for the next earnings of IONIS PHARMACEUTICALS INC (IONS) is -0.9 USD and the consensus revenue estimate is 199.47M USD.


Can you provide the consensus rating for IONIS PHARMACEUTICALS INC stock?

The consensus rating for IONIS PHARMACEUTICALS INC (IONS) is 81.3793 / 100 . This indicates that analysts generally have a positive outlook on the stock.