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ALNYLAM PHARMACEUTICALS INC (ALNY) Stock Fundamental Analysis

USA - NASDAQ:ALNY - US02043Q1076 - Common Stock

449.16 USD
-4.81 (-1.06%)
Last: 11/14/2025, 8:00:00 PM
449.16 USD
0 (0%)
After Hours: 11/14/2025, 8:00:00 PM
Fundamental Rating

4

We assign a fundamental rating of 4 out of 10 to ALNY. ALNY was compared to 531 industry peers in the Biotechnology industry. While ALNY seems to be doing ok healthwise, there are quite some concerns on its profitability. ALNY shows excellent growth, but is valued quite expensive already.


Dividend Valuation Growth Profitability Health

2

1. Profitability

1.1 Basic Checks

In the past year ALNY was profitable.
In the past year ALNY has reported a negative cash flow from operations.
ALNY had negative earnings in each of the past 5 years.
In the past 5 years ALNY reported 4 times negative operating cash flow.
ALNY Yearly Net Income VS EBIT VS OCF VS FCFALNY Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -200M -400M -600M -800M -1B

1.2 Ratios

Looking at the Return On Assets, with a value of -6.99%, ALNY belongs to the top of the industry, outperforming 86.63% of the companies in the same industry.
The Return On Equity of ALNY (-127.33%) is worse than 60.45% of its industry peers.
Industry RankSector Rank
ROA -6.99%
ROE -127.33%
ROIC N/A
ROA(3y)-16.65%
ROA(5y)-19.71%
ROE(3y)N/A
ROE(5y)N/A
ROIC(3y)N/A
ROIC(5y)N/A
ALNY Yearly ROA, ROE, ROICALNY Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 200 -200 400 -400 600

1.3 Margins

ALNY's Gross Margin of 83.64% is amongst the best of the industry. ALNY outperforms 86.44% of its industry peers.
ALNY's Gross Margin has been stable in the last couple of years.
The Profit Margin and Operating Margin are not available for ALNY so they could not be analyzed.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM 83.64%
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3Y0.88%
GM growth 5Y-0.68%
ALNY Yearly Profit, Operating, Gross MarginsALNY Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -200 -400 -600 -800 -1K

4

2. Health

2.1 Basic Checks

ALNY does not have a ROIC to compare to the WACC, probably because it is not profitable.
The number of shares outstanding for ALNY has been increased compared to 1 year ago.
ALNY has more shares outstanding than it did 5 years ago.
ALNY has a better debt/assets ratio than last year.
ALNY Yearly Shares OutstandingALNY Yearly Shares OutstandingYearly Shares Outstanding 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 20M 40M 60M 80M 100M
ALNY Yearly Total Debt VS Total AssetsALNY Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 1B 2B 3B 4B

2.2 Solvency

An Altman-Z score of 7.03 indicates that ALNY is not in any danger for bankruptcy at the moment.
ALNY has a Altman-Z score of 7.03. This is in the better half of the industry: ALNY outperforms 78.91% of its industry peers.
A Debt/Equity ratio of 4.10 is on the high side and indicates that ALNY has dependencies on debt financing.
ALNY's Debt to Equity ratio of 4.10 is on the low side compared to the rest of the industry. ALNY is outperformed by 82.11% of its industry peers.
Industry RankSector Rank
Debt/Equity 4.1
Debt/FCF N/A
Altman-Z 7.03
ROIC/WACCN/A
WACC8.69%
ALNY Yearly LT Debt VS Equity VS FCFALNY Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 500M -500M 1B 1.5B

2.3 Liquidity

ALNY has a Current Ratio of 2.80. This indicates that ALNY is financially healthy and has no problem in meeting its short term obligations.
Looking at the Current ratio, with a value of 2.80, ALNY is doing worse than 65.16% of the companies in the same industry.
ALNY has a Quick Ratio of 2.75. This indicates that ALNY is financially healthy and has no problem in meeting its short term obligations.
ALNY's Quick ratio of 2.75 is on the low side compared to the rest of the industry. ALNY is outperformed by 64.41% of its industry peers.
Industry RankSector Rank
Current Ratio 2.8
Quick Ratio 2.75
ALNY Yearly Current Assets VS Current LiabilitesALNY Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 1B 2B 3B

8

3. Growth

3.1 Past

ALNY shows a strong growth in Earnings Per Share. In the last year, the EPS has been growing by 119.47%, which is quite impressive.
The Revenue has grown by 22.97% in the past year. This is a very strong growth!
The Revenue has been growing by 59.21% on average over the past years. This is a very strong growth!
EPS 1Y (TTM)119.47%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%342.53%
Revenue 1Y (TTM)22.97%
Revenue growth 3Y38.61%
Revenue growth 5Y59.21%
Sales Q2Q%149.35%

3.2 Future

The Earnings Per Share is expected to grow by 74.37% on average over the next years. This is a very strong growth
Based on estimates for the next years, ALNY will show a very strong growth in Revenue. The Revenue will grow by 34.80% on average per year.
EPS Next Y167.09%
EPS Next 2Y119.91%
EPS Next 3Y95.36%
EPS Next 5Y74.37%
Revenue Next Year63.17%
Revenue Next 2Y51.94%
Revenue Next 3Y43.23%
Revenue Next 5Y34.8%

3.3 Evolution

Although the future Revenue growth is still strong, it is not able to hold up the even more excellent growth rate of the past years.
ALNY Yearly Revenue VS EstimatesALNY Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2014 2016 2018 2020 2022 2024 2026 2028 2030 2032 2B 4B 6B 8B 10B
ALNY Yearly EPS VS EstimatesALNY Yearly EPS VS EstimatesYearly EPS VS Estimates 2014 2016 2018 2020 2022 2024 2026 2028 2030 2032 0 10 20 30

2

4. Valuation

4.1 Price/Earnings Ratio

The Price/Earnings ratio is 880.71, which means the current valuation is very expensive for ALNY.
88.51% of the companies in the same industry are more expensive than ALNY, based on the Price/Earnings ratio.
Compared to an average S&P500 Price/Earnings ratio of 25.89, ALNY is valued quite expensively.
A Price/Forward Earnings ratio of 72.99 indicates a quite expensive valuation of ALNY.
ALNY's Price/Forward Earnings ratio is rather cheap when compared to the industry. ALNY is cheaper than 87.95% of the companies in the same industry.
ALNY is valuated expensively when we compare the Price/Forward Earnings ratio to 34.59, which is the current average of the S&P500 Index.
Industry RankSector Rank
PE 880.71
Fwd PE 72.99
ALNY Price Earnings VS Forward Price EarningsALNY Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 200 400 600 800

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
ALNY Per share dataALNY EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 5 10 15

4.3 Compensation for Growth

The high PEG Ratio(NY), which compensates the Price/Earnings for growth, indicates ALNY does not grow enough to justify the current Price/Earnings ratio.
A more expensive valuation may be justified as ALNY's earnings are expected to grow with 95.36% in the coming years.
PEG (NY)5.27
PEG (5Y)N/A
EPS Next 2Y119.91%
EPS Next 3Y95.36%

0

5. Dividend

5.1 Amount

ALNY does not give a dividend.
Industry RankSector Rank
Dividend Yield N/A

ALNYLAM PHARMACEUTICALS INC

NASDAQ:ALNY (11/14/2025, 8:00:00 PM)

After market: 449.16 0 (0%)

449.16

-4.81 (-1.06%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)10-30 2025-10-30/bmo
Earnings (Next)01-12 2026-01-12/amc
Inst Owners98.86%
Inst Owner Change-0.08%
Ins Owners0.2%
Ins Owner Change6.34%
Market Cap58.88B
Revenue(TTM)2.25B
Net Income(TTM)-319.09M
Analysts79.44
Price Target466.31 (3.82%)
Short Float %3.18%
Short Ratio3.68
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)2
Avg EPS beat(2)43.91%
Min EPS beat(2)30.6%
Max EPS beat(2)57.21%
EPS beat(4)3
Avg EPS beat(4)22.4%
Min EPS beat(4)-2.21%
Max EPS beat(4)57.21%
EPS beat(8)7
Avg EPS beat(8)54.7%
EPS beat(12)9
Avg EPS beat(12)30.18%
EPS beat(16)9
Avg EPS beat(16)17.36%
Revenue beat(2)1
Avg Revenue beat(2)7.46%
Min Revenue beat(2)-0.56%
Max Revenue beat(2)15.49%
Revenue beat(4)1
Avg Revenue beat(4)1.67%
Min Revenue beat(4)-7.88%
Max Revenue beat(4)15.49%
Revenue beat(8)4
Avg Revenue beat(8)19.36%
Revenue beat(12)6
Avg Revenue beat(12)11.5%
Revenue beat(16)7
Avg Revenue beat(16)6.42%
PT rev (1m)1.66%
PT rev (3m)9.92%
EPS NQ rev (1m)36.91%
EPS NQ rev (3m)309.27%
EPS NY rev (1m)25.14%
EPS NY rev (3m)204.95%
Revenue NQ rev (1m)2.88%
Revenue NQ rev (3m)10.97%
Revenue NY rev (1m)3.76%
Revenue NY rev (3m)23.78%
Valuation
Industry RankSector Rank
PE 880.71
Fwd PE 72.99
P/S 23.91
P/FCF N/A
P/OCF N/A
P/B 234.95
P/tB 234.95
EV/EBITDA N/A
EPS(TTM)0.51
EY0.11%
EPS(NY)6.15
Fwd EY1.37%
FCF(TTM)-0.4
FCFYN/A
OCF(TTM)-0.12
OCFYN/A
SpS18.78
BVpS1.91
TBVpS1.91
PEG (NY)5.27
PEG (5Y)N/A
Graham Number4.68
Profitability
Industry RankSector Rank
ROA -6.99%
ROE -127.33%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM 83.64%
FCFM N/A
ROA(3y)-16.65%
ROA(5y)-19.71%
ROE(3y)N/A
ROE(5y)N/A
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3Y0.88%
GM growth 5Y-0.68%
F-Score2
Asset Turnover0.54
Health
Industry RankSector Rank
Debt/Equity 4.1
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 64.69%
Cap/Sales 1.48%
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 2.8
Quick Ratio 2.75
Altman-Z 7.03
F-Score2
WACC8.69%
ROIC/WACCN/A
Cap/Depr(3y)112.53%
Cap/Depr(5y)140.08%
Cap/Sales(3y)3.96%
Cap/Sales(5y)7.04%
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)119.47%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%342.53%
EPS Next Y167.09%
EPS Next 2Y119.91%
EPS Next 3Y95.36%
EPS Next 5Y74.37%
Revenue 1Y (TTM)22.97%
Revenue growth 3Y38.61%
Revenue growth 5Y59.21%
Sales Q2Q%149.35%
Revenue Next Year63.17%
Revenue Next 2Y51.94%
Revenue Next 3Y43.23%
Revenue Next 5Y34.8%
EBIT growth 1Y-275.49%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year485.62%
EBIT Next 3Y150.05%
EBIT Next 5Y137.57%
FCF growth 1Y90.37%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y96.71%
OCF growth 3YN/A
OCF growth 5YN/A

ALNYLAM PHARMACEUTICALS INC / ALNY FAQ

Can you provide the ChartMill fundamental rating for ALNYLAM PHARMACEUTICALS INC?

ChartMill assigns a fundamental rating of 4 / 10 to ALNY.


What is the valuation status of ALNYLAM PHARMACEUTICALS INC (ALNY) stock?

ChartMill assigns a valuation rating of 2 / 10 to ALNYLAM PHARMACEUTICALS INC (ALNY). This can be considered as Overvalued.


How profitable is ALNYLAM PHARMACEUTICALS INC (ALNY) stock?

ALNYLAM PHARMACEUTICALS INC (ALNY) has a profitability rating of 2 / 10.


What is the financial health of ALNYLAM PHARMACEUTICALS INC (ALNY) stock?

The financial health rating of ALNYLAM PHARMACEUTICALS INC (ALNY) is 4 / 10.


What is the expected EPS growth for ALNYLAM PHARMACEUTICALS INC (ALNY) stock?

The Earnings per Share (EPS) of ALNYLAM PHARMACEUTICALS INC (ALNY) is expected to grow by 167.09% in the next year.