6.52 USD
-0.11 (-1.66%)
At close: Jan 30, 2026
6.4 USD
-0.12 (-1.84%)
After Hours: 1/30/2026, 8:01:27 PM
Overall KPTI gets a fundamental rating of 1 out of 10. We evaluated KPTI against 525 industry peers in the Biotechnology industry. KPTI may be in some trouble as it scores bad on both profitability and health. While showing a medium growth rate, KPTI is valued expensive at the moment.
1. Profitability
1.1 Basic Checks
- In the past year KPTI has reported negative net income.
- In the past year KPTI has reported a negative cash flow from operations.
- KPTI had negative earnings in each of the past 5 years.
- In the past 5 years KPTI always reported negative operating cash flow.
1.2 Ratios
- KPTI's Return On Assets of -129.50% is on the low side compared to the rest of the industry. KPTI is outperformed by 80.95% of its industry peers.
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| ROA | -129.5% | ||
| ROE | N/A | ||
| ROIC | N/A |
ROA(3y)-50.71%
ROA(5y)-51.1%
ROE(3y)N/A
ROE(5y)N/A
ROIC(3y)N/A
ROIC(5y)N/A
1.3 Margins
- The Gross Margin of KPTI (95.93%) is better than 96.00% of its industry peers.
- KPTI's Gross Margin has been stable in the last couple of years.
- The Profit Margin and Operating Margin are not available for KPTI so they could not be analyzed.
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| OM | N/A | ||
| PM (TTM) | N/A | ||
| GM | 95.93% |
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3Y-0.86%
GM growth 5Y0.37%
2. Health
2.1 Basic Checks
- KPTI does not have a ROIC to compare to the WACC, probably because it is not profitable.
- KPTI has more shares outstanding than it did 1 year ago.
- The number of shares outstanding for KPTI has been increased compared to 5 years ago.
- Compared to 1 year ago, KPTI has a worse debt to assets ratio.
2.2 Solvency
- Based on the Altman-Z score of -25.98, we must say that KPTI is in the distress zone and has some risk of bankruptcy.
- With a Altman-Z score value of -25.98, KPTI is not doing good in the industry: 85.33% of the companies in the same industry are doing better.
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| Debt/Equity | N/A | ||
| Debt/FCF | N/A | ||
| Altman-Z | -25.98 |
ROIC/WACCN/A
WACC7.92%
2.3 Liquidity
- KPTI has a Current Ratio of 1.03. This is a normal value and indicates that KPTI is financially healthy and should not expect problems in meeting its short term obligations.
- KPTI has a Current ratio of 1.03. This is amonst the worse of the industry: KPTI underperforms 85.90% of its industry peers.
- A Quick Ratio of 0.98 indicates that KPTI may have some problems paying its short term obligations.
- KPTI's Quick ratio of 0.98 is on the low side compared to the rest of the industry. KPTI is outperformed by 85.33% of its industry peers.
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| Current Ratio | 1.03 | ||
| Quick Ratio | 0.98 |
3. Growth
3.1 Past
- The earnings per share for KPTI have decreased strongly by -22.45% in the last year.
- The Revenue has decreased by -3.98% in the past year.
- Measured over the past years, KPTI shows a very strong growth in Revenue. The Revenue has been growing by 28.85% on average per year.
EPS 1Y (TTM)-22.45%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%2.05%
Revenue 1Y (TTM)-3.98%
Revenue growth 3Y-11.54%
Revenue growth 5Y28.85%
Sales Q2Q%13.57%
3.2 Future
- KPTI is expected to show quite a strong growth in Earnings Per Share. In the coming years, the EPS will grow by 15.23% yearly.
- Based on estimates for the next years, KPTI will show a very strong growth in Revenue. The Revenue will grow by 21.11% on average per year.
EPS Next Y-25.06%
EPS Next 2Y15.11%
EPS Next 3Y17.42%
EPS Next 5Y15.23%
Revenue Next Year-1.42%
Revenue Next 2Y-0.9%
Revenue Next 3Y17.92%
Revenue Next 5Y21.11%
3.3 Evolution
- Although the future Revenue growth is still strong, it is not able to hold up the even more excellent growth rate of the past years.
4. Valuation
4.1 Price/Earnings Ratio
- The Price/Earnings Ratio is negative for KPTI. In the last year negative earnings were reported.
- Besides the negative Price/Earnings Ratio, also the Forward Price/Earnings Ratio is negative for KPTI. No positive earnings are expected for the next year.
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| PE | N/A | ||
| Fwd PE | N/A |
4.2 Price Multiples
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| P/FCF | N/A | ||
| EV/EBITDA | N/A |
4.3 Compensation for Growth
- A more expensive valuation may be justified as KPTI's earnings are expected to grow with 17.42% in the coming years.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y15.11%
EPS Next 3Y17.42%
5. Dividend
5.1 Amount
- KPTI does not give a dividend.
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| Dividend Yield | 0% |
KARYOPHARM THERAPEUTICS INC / KPTI FAQ
Can you provide the ChartMill fundamental rating for KARYOPHARM THERAPEUTICS INC?
ChartMill assigns a fundamental rating of 1 / 10 to KPTI.
What is the valuation status for KPTI stock?
ChartMill assigns a valuation rating of 0 / 10 to KARYOPHARM THERAPEUTICS INC (KPTI). This can be considered as Overvalued.
How profitable is KARYOPHARM THERAPEUTICS INC (KPTI) stock?
KARYOPHARM THERAPEUTICS INC (KPTI) has a profitability rating of 1 / 10.
What is the expected EPS growth for KARYOPHARM THERAPEUTICS INC (KPTI) stock?
The Earnings per Share (EPS) of KARYOPHARM THERAPEUTICS INC (KPTI) is expected to decline by -25.06% in the next year.