Logo image of KPTI

KARYOPHARM THERAPEUTICS INC (KPTI) Stock Price, Forecast & Analysis

USA - Nasdaq - NASDAQ:KPTI - US48576U2050 - Common Stock

5.55 USD
+0.1 (+1.83%)
Last: 11/26/2025, 8:00:02 PM
5.55 USD
0 (0%)
After Hours: 11/26/2025, 8:00:02 PM

KPTI Key Statistics, Chart & Performance

Key Statistics
Market Cap88.41M
Revenue(TTM)142.53M
Net Income(TTM)-124.62M
Shares15.93M
Float15.07M
52 Week High12.9
52 Week Low3.51
Yearly DividendN/A
Dividend YieldN/A
EPS(TTM)-14.51
PEN/A
Fwd PEN/A
Earnings (Next)02-17 2026-02-17/amc
IPO2013-11-06
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology


KPTI short term performance overview.The bars show the price performance of KPTI in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 0 10 -10 20 -20 30

KPTI long term performance overview.The bars show the price performance of KPTI in the last 1, 2 and 3 years. 1 year 2 years 3 years -20 -40 -60 -80

The current stock price of KPTI is 5.55 USD. In the past month the price decreased by -8.72%. In the past year, price decreased by -56.22%.

KARYOPHARM THERAPEUTICS INC / KPTI Daily stock chart

KPTI Latest News, Press Relases and Analysis

KPTI Competitors/Peers

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REGN REGENERON PHARMACEUTICALS 17.43 83.16B
ALNY ALNYLAM PHARMACEUTICALS INC 872.78 58.35B
INSM INSMED INC N/A 43.23B
NTRA NATERA INC N/A 32.54B
BIIB BIOGEN INC 10.87 26.67B
UTHR UNITED THERAPEUTICS CORP 18.51 22.09B
INCY INCYTE CORP 16.46 20.63B
EXAS EXACT SCIENCES CORP N/A 19.21B

About KPTI

Company Profile

KPTI logo image Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is headquartered in Newton, Massachusetts and currently employs 279 full-time employees. The company went IPO on 2013-11-06. The firm is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The firm is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.

Company Info

KARYOPHARM THERAPEUTICS INC

85 Wells Avenue, Second Floor

Newton MASSACHUSETTS 02459 US

CEO: Michael G. Kauffman

Employees: 279

KPTI Company Website

KPTI Investor Relations

Phone: 16176580600

KARYOPHARM THERAPEUTICS INC / KPTI FAQ

Can you describe the business of KARYOPHARM THERAPEUTICS INC?

Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is headquartered in Newton, Massachusetts and currently employs 279 full-time employees. The company went IPO on 2013-11-06. The firm is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The firm is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.


What is the stock price of KARYOPHARM THERAPEUTICS INC today?

The current stock price of KPTI is 5.55 USD. The price increased by 1.83% in the last trading session.


Does KARYOPHARM THERAPEUTICS INC pay dividends?

KPTI does not pay a dividend.


What is the ChartMill rating of KARYOPHARM THERAPEUTICS INC stock?

KPTI has a ChartMill Technical rating of 0 out of 10 and a ChartMill Fundamental rating of 1 out of 10.


On which exchange is KPTI stock listed?

KPTI stock is listed on the Nasdaq exchange.


Would investing in KARYOPHARM THERAPEUTICS INC be a good decision?

This depends on your investment goals. Check the Technical and Fundamental Analysis tabs for insights on KPTI.


Can you provide the market cap for KARYOPHARM THERAPEUTICS INC?

KARYOPHARM THERAPEUTICS INC (KPTI) has a market capitalization of 88.41M USD. This makes KPTI a Micro Cap stock.


KPTI Technical Analysis


Chartmill TA Rating
Chartmill Setup Rating

KPTI Fundamental Analysis

ChartMill assigns a fundamental rating of 1 / 10 to KPTI. Both the profitability and financial health of KPTI have multiple concerns.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

KPTI Financial Highlights

Over the last trailing twelve months KPTI reported a non-GAAP Earnings per Share(EPS) of -14.51. The EPS decreased by -22.45% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -129.5%
ROE N/A
Debt/Equity N/A
Chartmill High Growth Momentum
EPS Q2Q%2.05%
Sales Q2Q%13.57%
EPS 1Y (TTM)-22.45%
Revenue 1Y (TTM)-3.98%

KPTI Forecast & Estimates

12 analysts have analysed KPTI and the average price target is 14.11 USD. This implies a price increase of 154.23% is expected in the next year compared to the current price of 5.55.

For the next year, analysts expect an EPS growth of -12.48% and a revenue growth -0.16% for KPTI


Analysts
Analysts81.67
Price Target14.11 (154.23%)
EPS Next Y-12.48%
Revenue Next Year-0.16%

KPTI Ownership

Ownership
Inst Owners51.13%
Ins Owners1.14%
Short Float %4.3%
Short Ratio3.49