KARYOPHARM THERAPEUTICS INC (KPTI) Stock Price & Overview

NASDAQ:KPTIUS48576U2050

Current stock price

7.63 USD
-0.1 (-1.29%)
At close:
7.7 USD
+0.07 (+0.92%)
After Hours:

The current stock price of KPTI is 7.63 USD. Today KPTI is down by -1.29%. In the past month the price decreased by -21.1%. In the past year, price increased by 18.85%.

KPTI Key Statistics

52-Week Range3.51 - 10.99
Current KPTI stock price positioned within its 52-week range.
1-Month Range7.29 - 10.99
Current KPTI stock price positioned within its 1-month range.
Market Cap
139.934M
P/E
N/A
Fwd P/E
N/A
EPS (TTM)
-13.13
Dividend Yield
N/A

KPTI Stock Performance

Today
-1.29%
1 Week
-2.80%
1 Month
-21.10%
3 Months
+9.94%
Longer-term
6 Months +41.04%
1 Year +18.85%
2 Years -66.31%
3 Years -86.92%
5 Years -95.16%
10 Years -94.30%

KPTI Stock Chart

KARYOPHARM THERAPEUTICS INC / KPTI Daily stock chart

KPTI Technical Analysis

ChartMill assigns a technical rating of 6 / 10 to KPTI. When comparing the yearly performance of all stocks, KPTI is one of the better performing stocks in the market, outperforming 80.09% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

KPTI Fundamental Analysis

ChartMill assigns a fundamental rating of 2 / 10 to KPTI. Both the profitability and financial health of KPTI have multiple concerns.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

KPTI Earnings

On February 12, 2026 KPTI reported an EPS of -2.22 and a revenue of 34.08M. The company missed EPS expectations (-9.14% surprise) and missed revenue expectations (-4.84% surprise).

Next Earnings DateMay 11, 2026
Last Earnings DateFeb 12, 2026
PeriodQ4 / 2025
EPS Reported-$2.22
Revenue Reported34.079M
EPS Surprise -9.14%
Revenue Surprise -4.84%

KPTI Forecast & Estimates

13 analysts have analysed KPTI and the average price target is 15.71 USD. This implies a price increase of 105.87% is expected in the next year compared to the current price of 7.63.

For the next year, analysts expect an EPS growth of 60.72% and a revenue growth -5.58% for KPTI


Analysts
Analysts83.08
Price Target15.71 (105.9%)
EPS Next Y60.72%
Revenue Next Year-5.58%

KPTI Groups

Sector & Classification

Sub-Industry
Biotechnology
Index Membership

KPTI Financial Highlights

Over the last trailing twelve months KPTI reported a non-GAAP Earnings per Share(EPS) of -13.13. The EPS decreased by -30.65% compared to the year before.


Income Statements
Revenue(TTM)146.07M
Net Income(TTM)-196.04M
Industry RankSector Rank
PM (TTM) N/A
ROA -180.82%
ROE N/A
Debt/Equity N/A
Chartmill High Growth Momentum
EPS Q2Q%38.33%
Sales Q2Q%11.58%
EPS 1Y (TTM)-30.65%
Revenue 1Y (TTM)0.57%

KPTI Ownership

Ownership
Inst Owners53.24%
Shares18.34M
Float17.11M
Ins Owners2.62%
Short Float %17.4%
Short Ratio4.96

About KPTI

Company Profile

KPTI logo image Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is headquartered in Newton, Massachusetts and currently employs 228 full-time employees. The company went IPO on 2013-11-06. The firm is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The firm is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.

Company Info

IPO: 2013-11-06

KARYOPHARM THERAPEUTICS INC

85 Wells Avenue, Second Floor

Newton MASSACHUSETTS 02459 US

CEO: Michael G. Kauffman

Employees: 228

KPTI Company Website

KPTI Investor Relations

Phone: 13026587581

KARYOPHARM THERAPEUTICS INC / KPTI FAQ

Can you describe the business of KARYOPHARM THERAPEUTICS INC?

Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is headquartered in Newton, Massachusetts and currently employs 228 full-time employees. The company went IPO on 2013-11-06. The firm is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The firm is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.


What is the current price of KPTI stock?

The current stock price of KPTI is 7.63 USD. The price decreased by -1.29% in the last trading session.


Does KARYOPHARM THERAPEUTICS INC pay dividends?

KPTI does not pay a dividend.


What is the ChartMill technical and fundamental rating of KPTI stock?

KPTI has a ChartMill Technical rating of 6 out of 10 and a ChartMill Fundamental rating of 2 out of 10.


How is the market expecting KPTI stock to perform?

13 analysts have analysed KPTI and the average price target is 15.71 USD. This implies a price increase of 105.87% is expected in the next year compared to the current price of 7.63.


Who owns KARYOPHARM THERAPEUTICS INC?

You can find the ownership structure of KARYOPHARM THERAPEUTICS INC (KPTI) on the Ownership tab.