Logo image of KPTI

KARYOPHARM THERAPEUTICS INC (KPTI) Stock Price, Forecast & Analysis

USA - NASDAQ:KPTI - US48576U2050 - Common Stock

5.8 USD
-0.16 (-2.68%)
Last: 10/31/2025, 8:00:02 PM
6 USD
+0.2 (+3.45%)
After Hours: 10/31/2025, 8:00:02 PM

KPTI Key Statistics, Chart & Performance

Key Statistics
Market Cap92.39M
Revenue(TTM)137.27M
Net Income(TTM)-123566000
Shares15.93M
Float15.07M
52 Week High14.24
52 Week Low3.51
Yearly DividendN/A
Dividend YieldN/A
EPS(TTM)-14.59
PEN/A
Fwd PEN/A
Earnings (Next)11-03 2025-11-03/bmo
IPO2013-11-06
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology


KPTI short term performance overview.The bars show the price performance of KPTI in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 0 20 -20 40

KPTI long term performance overview.The bars show the price performance of KPTI in the last 1, 2 and 3 years. 1 year 2 years 3 years -20 -40 -60 -80

The current stock price of KPTI is 5.8 USD. In the past month the price decreased by -9.09%. In the past year, price decreased by -57.19%.

KARYOPHARM THERAPEUTICS INC / KPTI Daily stock chart

KPTI Latest News, Press Relases and Analysis

KPTI Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
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TA
FA
PE
Market Cap
ABBV ABBVIE INC 23.07 385.18B
AMGN AMGEN INC 13.68 160.66B
GILD GILEAD SCIENCES INC 14.63 148.64B
VRTX VERTEX PHARMACEUTICALS INC 25.12 109.11B
REGN REGENERON PHARMACEUTICALS 14.48 69.08B
ALNY ALNYLAM PHARMACEUTICALS INC 350.8 59.78B
ARGX ARGENX SE - ADR 61.04 50.39B
INSM INSMED INC N/A 40.08B
ONC BEONE MEDICINES LTD-ADR 5.01 34.10B
NTRA NATERA INC N/A 27.30B
BNTX BIONTECH SE-ADR N/A 24.98B
BIIB BIOGEN INC 9.22 22.62B

About KPTI

Company Profile

KPTI logo image Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is headquartered in Newton, Massachusetts and currently employs 279 full-time employees. The company went IPO on 2013-11-06. The firm is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The firm is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.

Company Info

KARYOPHARM THERAPEUTICS INC

85 Wells Avenue, Second Floor

Newton MASSACHUSETTS 02459 US

CEO: Michael G. Kauffman

Employees: 279

KPTI Company Website

KPTI Investor Relations

Phone: 16176580600

KARYOPHARM THERAPEUTICS INC / KPTI FAQ

Can you describe the business of KARYOPHARM THERAPEUTICS INC?

Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is headquartered in Newton, Massachusetts and currently employs 279 full-time employees. The company went IPO on 2013-11-06. The firm is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The firm is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.


What is the stock price of KARYOPHARM THERAPEUTICS INC today?

The current stock price of KPTI is 5.8 USD. The price decreased by -2.68% in the last trading session.


Does KARYOPHARM THERAPEUTICS INC pay dividends?

KPTI does not pay a dividend.


What is the ChartMill rating of KARYOPHARM THERAPEUTICS INC stock?

KPTI has a ChartMill Technical rating of 2 out of 10 and a ChartMill Fundamental rating of 1 out of 10.


On which exchange is KPTI stock listed?

KPTI stock is listed on the Nasdaq exchange.


Would investing in KARYOPHARM THERAPEUTICS INC be a good decision?

This depends on your investment goals. Check the Technical and Fundamental Analysis tabs for insights on KPTI.


Can you provide the market cap for KARYOPHARM THERAPEUTICS INC?

KARYOPHARM THERAPEUTICS INC (KPTI) has a market capitalization of 92.39M USD. This makes KPTI a Micro Cap stock.


KPTI Technical Analysis

ChartMill assigns a technical rating of 2 / 10 to KPTI. When comparing the yearly performance of all stocks, KPTI is a bad performer in the overall market: 75.72% of all stocks are doing better.


Chartmill TA Rating
Chartmill Setup Rating

KPTI Fundamental Analysis

ChartMill assigns a fundamental rating of 1 / 10 to KPTI. Both the profitability and financial health of KPTI have multiple concerns.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

KPTI Financial Highlights

Over the last trailing twelve months KPTI reported a non-GAAP Earnings per Share(EPS) of -14.59. The EPS decreased by -17.19% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -117.82%
ROE N/A
Debt/Equity N/A
Chartmill High Growth Momentum
EPS Q2Q%-292%
Sales Q2Q%-11.35%
EPS 1Y (TTM)-17.19%
Revenue 1Y (TTM)-5.76%

KPTI Forecast & Estimates

12 analysts have analysed KPTI and the average price target is 15.98 USD. This implies a price increase of 175.52% is expected in the next year compared to the current price of 5.8.

For the next year, analysts expect an EPS growth of -12.48% and a revenue growth -0.16% for KPTI


Analysts
Analysts80
Price Target15.98 (175.52%)
EPS Next Y-12.48%
Revenue Next Year-0.16%

KPTI Ownership

Ownership
Inst Owners51.13%
Ins Owners1.14%
Short Float %9.55%
Short Ratio6.54