Logo image of KPTI

KARYOPHARM THERAPEUTICS INC (KPTI) Stock Price, Quote, News and Overview

NASDAQ:KPTI - Nasdaq - US48576U2050 - Common Stock - Currency: USD

4.48  -0.07 (-1.54%)

Premarket: 4.6 +0.12 (+2.68%)

KPTI Quote, Performance and Key Statistics

KARYOPHARM THERAPEUTICS INC

NASDAQ:KPTI (5/28/2025, 8:00:02 PM)

Premarket: 4.6 +0.12 (+2.68%)

4.48

-0.07 (-1.54%)

Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology
Statistics
52 Week High17.4
52 Week Low3.51
Market Cap38.71M
Shares8.64M
Float8.08M
Yearly DividendN/A
Dividend YieldN/A
PEN/A
Fwd PEN/A
Earnings (Next)08-04 2025-08-04/bmo
IPO11-06 2013-11-06


KPTI short term performance overview.The bars show the price performance of KPTI in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months -20 -40 -60

KPTI long term performance overview.The bars show the price performance of KPTI in the last 1, 2 and 3 years. 1 year 2 years 3 years -20 -40 -60 -80

The current stock price of KPTI is 4.48 USD. In the past month the price decreased by -29.45%. In the past year, price decreased by -69.18%.

KARYOPHARM THERAPEUTICS INC / KPTI Daily stock chart

KPTI Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
Full List
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TA
FA
PE
Market Cap
ABBV ABBVIE INC 17.83 323.41B
AMGN AMGEN INC 13.41 149.70B
GILD GILEAD SCIENCES INC 14.01 134.89B
VRTX VERTEX PHARMACEUTICALS INC N/A 114.30B
REGN REGENERON PHARMACEUTICALS 13.36 63.90B
ALNY ALNYLAM PHARMACEUTICALS INC N/A 37.23B
ARGX ARGENX SE - ADR 98.17 35.18B
ONC BEIGENE LTD-ADR 6.15 25.99B
BNTX BIONTECH SE-ADR N/A 23.45B
NTRA NATERA INC N/A 22.01B
SMMT SUMMIT THERAPEUTICS INC N/A 19.34B
BIIB BIOGEN INC 8.06 18.69B

About KPTI

Company Profile

KPTI logo image Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is headquartered in Newton, Massachusetts and currently employs 279 full-time employees. The company went IPO on 2013-11-06. The firm is engaged in the discovery, development and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company is developing and commercializing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead asset, XPOVIO (selinexor), is marketed in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma who have received at least one prior therapy. The firm is engaged in evaluating selinexor in certain hematological and solid tumor malignancies, including endometrial cancer, mycosis fungoides (MF) and diffuse large B-cell lymphoma (DLBCL). The Company’s product candidate, eltanexor, is an oral SINE compound like selinexor, that selectively blocks the nuclear export protein XPO1.

Company Info

KARYOPHARM THERAPEUTICS INC

85 Wells Avenue, Second Floor

Newton MASSACHUSETTS 02459 US

CEO: Michael G. Kauffman

Employees: 279

KPTI Company Website

KPTI Investor Relations

Phone: 16176580600

KARYOPHARM THERAPEUTICS INC / KPTI FAQ

What is the stock price of KARYOPHARM THERAPEUTICS INC today?

The current stock price of KPTI is 4.48 USD. The price decreased by -1.54% in the last trading session.


What is the ticker symbol for KARYOPHARM THERAPEUTICS INC stock?

The exchange symbol of KARYOPHARM THERAPEUTICS INC is KPTI and it is listed on the Nasdaq exchange.


On which exchange is KPTI stock listed?

KPTI stock is listed on the Nasdaq exchange.


What is the price forecast or stock price prediction for KARYOPHARM THERAPEUTICS INC stock?

13 analysts have analysed KPTI and the average price target is 49.62 USD. This implies a price increase of 1007.5% is expected in the next year compared to the current price of 4.48. Check the KARYOPHARM THERAPEUTICS INC stock analysts ratings, price target forecast and up-and down grades for more detailed information.


What is KARYOPHARM THERAPEUTICS INC worth?

KARYOPHARM THERAPEUTICS INC (KPTI) has a market capitalization of 38.71M USD. This makes KPTI a Nano Cap stock.


How many employees does KARYOPHARM THERAPEUTICS INC have?

KARYOPHARM THERAPEUTICS INC (KPTI) currently has 279 employees.


What are the support and resistance levels for KARYOPHARM THERAPEUTICS INC (KPTI) stock?

KARYOPHARM THERAPEUTICS INC (KPTI) has a support level at 4.47 and a resistance level at 6.28. Check the full technical report for a detailed analysis of KPTI support and resistance levels.


Is KARYOPHARM THERAPEUTICS INC (KPTI) expected to grow?

The Revenue of KARYOPHARM THERAPEUTICS INC (KPTI) is expected to decline by -2.58% in the next year. Check the estimates tab for more information on the KPTI EPS, Sales, EBIT and EBITDA future analyst estimates.


Should I buy KARYOPHARM THERAPEUTICS INC (KPTI) stock?

There is no straightforward answer here. It depends on your investment strategy as different types of investors will look at different aspects. In any case it is important to make an informed decision and these pages can help you forming an opinion:


Does KARYOPHARM THERAPEUTICS INC (KPTI) stock pay dividends?

KPTI does not pay a dividend.


When does KARYOPHARM THERAPEUTICS INC (KPTI) report earnings?

KARYOPHARM THERAPEUTICS INC (KPTI) will report earnings on 2025-08-04, before the market open.


What is the Price/Earnings (PE) ratio of KARYOPHARM THERAPEUTICS INC (KPTI)?

KARYOPHARM THERAPEUTICS INC (KPTI) does not have a PE ratio as the earnings reported over the last twelve months were negative (-8.02).


What is the Short Interest ratio of KARYOPHARM THERAPEUTICS INC (KPTI) stock?

The outstanding short interest for KARYOPHARM THERAPEUTICS INC (KPTI) is 24.71% of its float. Check the ownership tab for more information on the KPTI short interest.


KPTI Technical Analysis


Chartmill TA Rating
Chartmill Setup Rating

KPTI Fundamental Analysis

ChartMill assigns a fundamental rating of 2 / 10 to KPTI. KPTI may be in some trouble as it scores bad on both profitability and health.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

KPTI Financial Highlights

Over the last trailing twelve months KPTI reported a non-GAAP Earnings per Share(EPS) of -8.02. The EPS increased by 57.9% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -48.96%
ROE N/A
Debt/Equity N/A
Chartmill High Growth Momentum
EPS Q2Q%42.29%
Sales Q2Q%-9.39%
EPS 1Y (TTM)57.9%
Revenue 1Y (TTM)1.18%

KPTI Ownership and Analysts

ChartMill assigns a Buy % Consensus number of 83% to KPTI. The Buy consensus is the average rating of analysts ratings from 13 analysts.

For the next year, analysts expect an EPS growth of -45.56% and a revenue growth -2.58% for KPTI


Ownership
Inst Owners49.37%
Ins Owners0.81%
Short Float %24.71%
Short Ratio15.26
Analysts
Analysts83.08
Price Target49.62 (1007.59%)
EPS Next Y-45.56%
Revenue Next Year-2.58%