KARYOPHARM THERAPEUTICS INC (KPTI) Earnings History & Surprises

NASDAQ:KPTIUS48576U2050

Current stock price

6.66 USD
-0.97 (-12.71%)
At close:
6.3 USD
-0.36 (-5.41%)
Pre-Market:

KPTI Earnings overview

Past quarterly earnings results for KARYOPHARM THERAPEUTICS INC (KPTI), including EPS and revenue actuals, analyst estimates, and surprise percentages. This page focuses on historical performance (not forecasts).

Earnings Snapshot

Next Earnings Date

Upcoming
Release Date
May 11, 2026
Period
Q1 / 2026
EPS Estimate
-$1.33
Revenue Estimate
32.4M

Last Reported

Most Recent
Release Date
Feb 12, 2026
Period
Q4 / 2025
EPS Reported
-$2.22
EPS Surprise
-9.14%
Revenue Surprise
-4.84%

Beat Rate

Last 8 Quarters
56%
EPS and Revenue beats vs estimates

Quarterly Earnings Historical Results

EPS & Revenue History (in USD): Actual vs estimated values, surprises, q2q growth and acceleration numbers quarterly history.

QuarterEPSEPS EstEPS SurpriseEPS Q2QRevenueRevenue EstRevenue SurpriseRevenue Q2Q
Q4 2025 -2.22 -2.03 -9.14% 38.33% 34.079M 35.814M -4.84% 11.58%
Q3 2025 -3.82 -3.19 -19.63% 2.05% 44.044M 42.036M 4.78% 13.57%
Q2 2025 -4.32 -4.18 -3.34% -292.00% 37.929M 37.674M 0.68% -11.35%
Q1 2025 -2.77 -4.26 35.04% 42.29% 30.015M 35.947M -16.50% -9.39%
Q4 2024 -3.60 -4.00 10.00% 33.33% 30.542M 35.562M -14.12% -9.50%
Q3 2024 -3.90 -4.02 3.03% 13.33% 38.783M 38.544M 0.62% 7.70%
Q2 2024 2.25 -4.57 149.25% 151.72% 42.786M 36.903M 15.94% 13.86%
Q1 2024 -4.80 -5.11 6.03% -6.67% 33.126M 35.162M -5.79% -14.40%
Q4 2023 -5.40 -4.74 -13.96% 16.28% 33.747M 36.113M -6.55% 0.44%
Q3 2023 -4.50 -4.28 -5.04% 33.33% 36.009M 38.025M -5.30% -0.25%
Q2 2023 -4.35 -5.24 16.92% 53.23% 37.579M 36.736M 2.29% -5.34%
Q1 2023 -4.50 -5.63 20.12% 43.40% 38.698M 37.337M 3.65% -18.87%
Q4 2022 -6.45 -5.40 -19.42% -193.48% 33.6M 35.821M -6.20% -73.40%
Q3 2022 -6.75 -8.65 21.99% 34.78% 36.1M 35.253M 2.40% -4.24%
Q2 2022 -9.30 -9.69 4.02% 12.68% 39.7M 36.303M 9.36% 75.66%
Q1 2022 -7.95 -9.65 17.65% 31.17% 47.7M 34.854M 36.86% 104.72%
Q4 2021 6.90 -7.89 187.47% 177.97% 126.3M 40.868M 209.04% 259.83%
Q3 2021 -10.35 -10.30 -0.47% 5.48% 37.7M 26.32M 43.24% 77.00%
Q2 2021 -10.65 -11.46 7.07% -12.70% 22.6M 26.153M -13.59% -32.54%
Q1 2021 -11.55 -10.88 -6.17% 1.28% 23.3M 25.672M -9.24% 28.73%
Q4 2020 -8.85 -9.06 2.29% - 35.1M 29.961M 17.15% -
Q3 2020 -10.95 -11.06 1.01% - 21.3M 21.882M -2.66% -
Q2 2020 -9.45 -8.89 -6.31% - 33.5M 27.97M 19.77% -
Q1 2020 -11.70 -10.61 -10.23% - 18.1M 21.708M -16.62% -

Notes

  • EPS and Revenue values are non-GAAP when available, otherwise GAAP.
  • Surprise % is (Actual - Estimate) / |Estimate|. Green indicates positive surprise, red negative.
  • Q2Q % is quarter-over-quarter growth. Green indicates growth, red indicates decline.
  • Green right border indicates acceleration for sales or earnings growth. Acceleration is the case when the current Q2Q is above the previous Q2Q.

Earnings Q2Q Performance Trends

EPS Historical Q2Q growth and Acceleration

KPTI EPS Q2Q GrowthKPTI EPS Q2Q GrowthEPS Q2Q Growth Q1/21 Q3/21 Q1/22 Q3/22 Q1/23 Q3/23 Q1/24 Q3/24 Q1/25 Q3/25 Q1/26 Q3/26 0 100 -100 -200

Revenue Historical Q2Q growth and Acceleration

KPTI Revenue Q2Q GrowthKPTI Revenue Q2Q GrowthRevenue Q2Q Growth Q1/21 Q3/21 Q1/22 Q3/22 Q1/23 Q3/23 Q1/24 Q3/24 Q1/25 Q3/25 Q1/26 Q3/26 0 100 200

Surprise distribution (Last 4 Quarters)

EPS beat statistics

EPS beat (4)
1
Average EPS beat (4)
0.74%
Max EPS beat (4)
35.04%
Min EPS beat (4)
-19.63%

Revenue beat statistics

Revenue beat (4)
2
Average Revenue beat (4)
-3.97%
Max Revenue beat (4)
4.78%
Min Revenue beat (4)
-16.50%

Analysis

In the last 4 quarters, KPTI has beaten EPS estimates in 1 out of 4 releases
KPTI has beaten revenue estimates in 2 out of the last 4 releases
In the last 4 quarters, KPTI has beaten the EPS estimates by 0.7% on average.
In the last 4 quarters, KPTI reported -4.0% below the revenue estimates on average.

KARYOPHARM THERAPEUTICS INC / KPTI Earnings FAQ

Can you provide the last earnings date for KARYOPHARM THERAPEUTICS INC?

KARYOPHARM THERAPEUTICS INC (KPTI) last reported earnings on 2/12/2026.

Did KPTI stock beat earnings estimates in the most recent quarter?

KARYOPHARM THERAPEUTICS INC (KPTI) missed EPS estimates and missed revenue estimates in the most recent quarter.

How often does KARYOPHARM THERAPEUTICS INC (KPTI) beat earnings estimates?

In the last 4 quarters, KARYOPHARM THERAPEUTICS INC (KPTI) has beaten EPS estimates in 1 out of 4 releases.