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DENALI THERAPEUTICS INC (DNLI) Stock Fundamental Analysis

NASDAQ:DNLI - Nasdaq - US24823R1059 - Common Stock - Currency: USD

14.52  -0.83 (-5.41%)

After market: 14.52 0 (0%)

Fundamental Rating

2

Taking everything into account, DNLI scores 2 out of 10 in our fundamental rating. DNLI was compared to 560 industry peers in the Biotechnology industry. While DNLI seems to be doing ok healthwise, there are quite some concerns on its profitability. DNLI has a expensive valuation and it also scores bad on growth.


Dividend Valuation Growth Profitability Health

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1

1. Profitability

1.1 Basic Checks

DNLI had negative earnings in the past year.
In the past year DNLI has reported a negative cash flow from operations.
In the past 5 years DNLI reported 4 times negative net income.
DNLI had negative operating cash flow in 4 of the past 5 years.
DNLI Yearly Net Income VS EBIT VS OCF VS FCFDNLI Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 200M -200M 400M -400M

1.2 Ratios

With a decent Return On Assets value of -30.77%, DNLI is doing good in the industry, outperforming 65.48% of the companies in the same industry.
Looking at the Return On Equity, with a value of -34.38%, DNLI is in the better half of the industry, outperforming 74.73% of the companies in the same industry.
Industry RankSector Rank
ROA -30.77%
ROE -34.38%
ROIC N/A
ROA(3y)-21.89%
ROA(5y)-16.39%
ROE(3y)-26.58%
ROE(5y)-20.75%
ROIC(3y)N/A
ROIC(5y)N/A
DNLI Yearly ROA, ROE, ROICDNLI Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -10 -20 -30 -40 -50

1.3 Margins

The Profit Margin and Operating Margin and Gross Margin are not available for DNLI so they could not be analyzed.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM N/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
DNLI Yearly Profit, Operating, Gross MarginsDNLI Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -200 -400 -600

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5

2. Health

2.1 Basic Checks

DNLI does not have a ROIC to compare to the WACC, probably because it is not profitable.
Compared to 1 year ago, DNLI has more shares outstanding
Compared to 5 years ago, DNLI has more shares outstanding
Compared to 1 year ago, DNLI has a worse debt to assets ratio.
DNLI Yearly Shares OutstandingDNLI Yearly Shares OutstandingYearly Shares Outstanding 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 50M 100M
DNLI Yearly Total Debt VS Total AssetsDNLI Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 500M 1B 1.5B

2.2 Solvency

DNLI has an Altman-Z score of 6.65. This indicates that DNLI is financially healthy and has little risk of bankruptcy at the moment.
DNLI has a Altman-Z score of 6.65. This is amongst the best in the industry. DNLI outperforms 82.03% of its industry peers.
A Debt/Equity ratio of 0.00 indicates that DNLI is not too dependend on debt financing.
With a Debt to Equity ratio value of 0.00, DNLI perfoms like the industry average, outperforming 44.48% of the companies in the same industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z 6.65
ROIC/WACCN/A
WACC9.79%
DNLI Yearly LT Debt VS Equity VS FCFDNLI Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 500M 1B

2.3 Liquidity

A Current Ratio of 8.46 indicates that DNLI has no problem at all paying its short term obligations.
The Current ratio of DNLI (8.46) is better than 72.78% of its industry peers.
DNLI has a Quick Ratio of 8.46. This indicates that DNLI is financially healthy and has no problem in meeting its short term obligations.
Looking at the Quick ratio, with a value of 8.46, DNLI is in the better half of the industry, outperforming 72.78% of the companies in the same industry.
Industry RankSector Rank
Current Ratio 8.46
Quick Ratio 8.46
DNLI Yearly Current Assets VS Current LiabilitesDNLI Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 500M 1B

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3

3. Growth

3.1 Past

The earnings per share for DNLI have decreased strongly by -151.89% in the last year.
DNLI shows a very negative growth in Revenue. In the last year, the Revenue has decreased by -100.00%.
EPS 1Y (TTM)-151.89%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%0%
Revenue 1Y (TTM)-100%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%N/A

3.2 Future

The Earnings Per Share is expected to grow by 14.10% on average over the next years. This is quite good.
DNLI is expected to show a strong growth in Revenue. In the coming years, the Revenue will grow by 141.77% yearly.
EPS Next Y-15.44%
EPS Next 2Y-4.74%
EPS Next 3Y2.47%
EPS Next 5Y14.1%
Revenue Next Year159.36%
Revenue Next 2Y231.36%
Revenue Next 3Y203.79%
Revenue Next 5Y141.77%

3.3 Evolution

DNLI Yearly Revenue VS EstimatesDNLI Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 500M 1B 1.5B
DNLI Yearly EPS VS EstimatesDNLI Yearly EPS VS EstimatesYearly EPS VS Estimates 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 0 1 -1 2 -2 -3

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0

4. Valuation

4.1 Price/Earnings Ratio

The Price/Earnings Ratio is negative for DNLI. In the last year negative earnings were reported.
Besides the negative Price/Earnings Ratio, also the Forward Price/Earnings Ratio is negative for DNLI. No positive earnings are expected for the next year.
Industry RankSector Rank
PE N/A
Fwd PE N/A
DNLI Price Earnings VS Forward Price EarningsDNLI Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 20 40 60 80 100

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
DNLI Per share dataDNLI EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 2 -2 4 6 8

4.3 Compensation for Growth

PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y-4.74%
EPS Next 3Y2.47%

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0

5. Dividend

5.1 Amount

No dividends for DNLI!.
Industry RankSector Rank
Dividend Yield N/A

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DENALI THERAPEUTICS INC

NASDAQ:DNLI (7/11/2025, 8:05:46 PM)

After market: 14.52 0 (0%)

14.52

-0.83 (-5.41%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)05-06 2025-05-06/amc
Earnings (Next)07-30 2025-07-30
Inst Owners93.67%
Inst Owner Change0%
Ins Owners4.85%
Ins Owner Change0.31%
Market Cap2.11B
Analysts88
Price Target33.59 (131.34%)
Short Float %9.13%
Short Ratio7.98
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)1
Avg EPS beat(2)8.87%
Min EPS beat(2)-0.5%
Max EPS beat(2)18.24%
EPS beat(4)2
Avg EPS beat(4)6.14%
Min EPS beat(4)-8.8%
Max EPS beat(4)18.24%
EPS beat(8)4
Avg EPS beat(8)38.34%
EPS beat(12)6
Avg EPS beat(12)26.96%
EPS beat(16)6
Avg EPS beat(16)9.31%
Revenue beat(2)0
Avg Revenue beat(2)-100%
Min Revenue beat(2)-100%
Max Revenue beat(2)-100%
Revenue beat(4)0
Avg Revenue beat(4)-100%
Min Revenue beat(4)-100%
Max Revenue beat(4)-100%
Revenue beat(8)2
Avg Revenue beat(8)184.22%
Revenue beat(12)4
Avg Revenue beat(12)121.08%
Revenue beat(16)4
Avg Revenue beat(16)75.15%
PT rev (1m)0%
PT rev (3m)-13.35%
EPS NQ rev (1m)0%
EPS NQ rev (3m)0.06%
EPS NY rev (1m)-1.08%
EPS NY rev (3m)-6.95%
Revenue NQ rev (1m)0%
Revenue NQ rev (3m)-7.7%
Revenue NY rev (1m)-0.57%
Revenue NY rev (3m)-10.66%
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S N/A
P/FCF N/A
P/OCF N/A
P/B 1.72
P/tB 1.72
EV/EBITDA N/A
EPS(TTM)-2.67
EYN/A
EPS(NY)-2.93
Fwd EYN/A
FCF(TTM)-2.5
FCFYN/A
OCF(TTM)-2.39
OCFYN/A
SpS0
BVpS8.46
TBVpS8.46
PEG (NY)N/A
PEG (5Y)N/A
Profitability
Industry RankSector Rank
ROA -30.77%
ROE -34.38%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM N/A
FCFM N/A
ROA(3y)-21.89%
ROA(5y)-16.39%
ROE(3y)-26.58%
ROE(5y)-20.75%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexcg growth 3YN/A
ROICexcg growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score1
Asset Turnover0
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 176.96%
Cap/Sales N/A
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 8.46
Quick Ratio 8.46
Altman-Z 6.65
F-Score1
WACC9.79%
ROIC/WACCN/A
Cap/Depr(3y)141.82%
Cap/Depr(5y)112.16%
Cap/Sales(3y)N/A
Cap/Sales(5y)N/A
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)-151.89%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%0%
EPS Next Y-15.44%
EPS Next 2Y-4.74%
EPS Next 3Y2.47%
EPS Next 5Y14.1%
Revenue 1Y (TTM)-100%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%N/A
Revenue Next Year159.36%
Revenue Next 2Y231.36%
Revenue Next 3Y203.79%
Revenue Next 5Y141.77%
EBIT growth 1Y-155.18%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year-3.7%
EBIT Next 3Y5.04%
EBIT Next 5Y18.12%
FCF growth 1Y1.97%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y2.88%
OCF growth 3YN/A
OCF growth 5YN/A