DENALI THERAPEUTICS INC (DNLI) Stock Price & Overview

NASDAQ:DNLIUS24823R1059

Current stock price

20.315 USD
+0.19 (+0.92%)
Last:

The current stock price of DNLI is 20.315 USD. Today DNLI is up by 0.92%. In the past month the price decreased by -4.55%. In the past year, price increased by 28.38%.

DNLI Key Statistics

52-Week Range12.58 - 23.77
Current DNLI stock price positioned within its 52-week range.
1-Month Range17.86 - 23.46
Current DNLI stock price positioned within its 1-month range.
Market Cap
3.222B
P/E
N/A
Fwd P/E
N/A
EPS (TTM)
-2.97
Dividend Yield
N/A

DNLI Stock Performance

Today
+0.92%
1 Week
-0.15%
1 Month
-4.55%
3 Months
-0.59%
Longer-term
6 Months +26.13%
1 Year +28.38%
2 Years +30.38%
3 Years -18.96%
5 Years -66.69%
10 Years N/A

DNLI Stock Chart

DENALI THERAPEUTICS INC / DNLI Daily stock chart

DNLI Stock Screens

DNLI currently appears in the following ChartMill screener lists.

DNLI Technical Analysis

ChartMill assigns a technical rating of 4 / 10 to DNLI. When comparing the yearly performance of all stocks, DNLI turns out to be only a medium performer in the overall market: it outperformed 66.03% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

DNLI Fundamental Analysis

ChartMill assigns a fundamental rating of 2 / 10 to DNLI. The financial health of DNLI is average, but there are quite some concerns on its profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

DNLI Earnings

Next Earnings DateMay 4, 2026
Last Earnings DateFeb 26, 2026
PeriodQ4 / 2025
EPS Reported-$0.73
Revenue Reported
EPS Surprise 3.82%
Revenue Surprise -100.00%

DNLI Forecast & Estimates

25 analysts have analysed DNLI and the average price target is 36.72 USD. This implies a price increase of 80.75% is expected in the next year compared to the current price of 20.315.

For the next year, analysts expect an EPS growth of 7.09% and a revenue growth 2718.14% for DNLI


Analysts
Analysts87.2
Price Target36.72 (80.75%)
EPS Next Y7.09%
Revenue Next Year2718.14%

DNLI Groups

Sector & Classification

DNLI Financial Highlights

Over the last trailing twelve months DNLI reported a non-GAAP Earnings per Share(EPS) of -2.97. The EPS decreased by -11.24% compared to the year before.


Income Statements
Revenue(TTM)N/A
Net Income(TTM)-512.54M
Industry RankSector Rank
PM (TTM) N/A
ROA -44.77%
ROE -50.56%
Debt/Equity 0.01
Chartmill High Growth Momentum
EPS Q2Q%-8.96%
Sales Q2Q%N/A
EPS 1Y (TTM)-11.24%
Revenue 1Y (TTM)N/A

DNLI Ownership

Ownership
Inst Owners97.49%
Shares158.59M
Float143.13M
Ins Owners4.26%
Short Float %10.77%
Short Ratio8.69

About DNLI

Company Profile

DNLI logo image Denali Therapeutics, Inc. is a biopharmaceutical company, which engages in the development and commercialization of a portfolio of product candidates for neurodegenerative diseases. The company is headquartered in South San Francisco, California and currently employs 503 full-time employees. The company went IPO on 2017-12-08. The firm is focused on developing a broad portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for the treatment of neurodegenerative diseases and lysosomal storage diseases. The company has developed a technology, called the TransportVehicle (TV), to address the BBB challenge. Its advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (MPS II or Hunter syndrome). Its TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for MPS IIIA (Sanfilippo syndrome) and DNL593 (PTV:PGRN) for frontotemporal dementia-granulin (FTD-GRN). Its small-molecule clinical development portfolio includes BIIB122/DNL151 (small molecule LRRK2 inhibitor) for Parkinson’s disease; and DNL343 (small molecule eIF2B activator) for amyotrophic lateral sclerosis (ALS). The company is also exploring programs in oncology, inflammation, and other diseases.

Company Info

IPO: 2017-12-08

DENALI THERAPEUTICS INC

161 Oyster Point Blvd.

South San Francisco CALIFORNIA 94080 US

CEO: Ryan J. Watts

Employees: 503

DNLI Company Website

DNLI Investor Relations

Phone: 16508668547

DENALI THERAPEUTICS INC / DNLI FAQ

What does DENALI THERAPEUTICS INC do?

Denali Therapeutics, Inc. is a biopharmaceutical company, which engages in the development and commercialization of a portfolio of product candidates for neurodegenerative diseases. The company is headquartered in South San Francisco, California and currently employs 503 full-time employees. The company went IPO on 2017-12-08. The firm is focused on developing a broad portfolio of product candidates engineered to cross the blood-brain barrier (BBB) for the treatment of neurodegenerative diseases and lysosomal storage diseases. The company has developed a technology, called the TransportVehicle (TV), to address the BBB challenge. Its advanced TV-enabled program is tividenofusp alfa (DNL310, ETV:IDS) for the potential treatment of mucopolysaccharidosis II (MPS II or Hunter syndrome). Its TV-enabled clinical development portfolio also includes DNL126 (ETV:SGSH) for MPS IIIA (Sanfilippo syndrome) and DNL593 (PTV:PGRN) for frontotemporal dementia-granulin (FTD-GRN). Its small-molecule clinical development portfolio includes BIIB122/DNL151 (small molecule LRRK2 inhibitor) for Parkinson’s disease; and DNL343 (small molecule eIF2B activator) for amyotrophic lateral sclerosis (ALS). The company is also exploring programs in oncology, inflammation, and other diseases.


Can you provide the latest stock price for DENALI THERAPEUTICS INC?

The current stock price of DNLI is 20.315 USD. The price increased by 0.92% in the last trading session.


What is the dividend status of DENALI THERAPEUTICS INC?

DNLI does not pay a dividend.


What is the ChartMill technical and fundamental rating of DNLI stock?

DNLI has a ChartMill Technical rating of 4 out of 10 and a ChartMill Fundamental rating of 2 out of 10.


What is the Price/Earnings (PE) ratio of DENALI THERAPEUTICS INC (DNLI)?

DENALI THERAPEUTICS INC (DNLI) does not have a PE ratio as the earnings reported over the last twelve months were negative (-2.97).


Should I buy DNLI stock?

This depends on your investment goals. Check the Technical and Fundamental Analysis tabs for insights on DNLI.


Can you provide the market cap for DENALI THERAPEUTICS INC?

DENALI THERAPEUTICS INC (DNLI) has a market capitalization of 3.22B USD. This makes DNLI a Mid Cap stock.