Logo image of ZYME

ZYMEWORKS INC (ZYME) Stock Fundamental Analysis

USA - Nasdaq - NASDAQ:ZYME - US98985Y1082 - Common Stock

27.23 USD
+0.83 (+3.14%)
Last: 12/19/2025, 8:22:48 PM
27.32 USD
+0.09 (+0.33%)
After Hours: 12/19/2025, 8:22:48 PM
Fundamental Rating

4

Overall ZYME gets a fundamental rating of 4 out of 10. We evaluated ZYME against 529 industry peers in the Biotechnology industry. ZYME has a great financial health rating, but its profitability evaluates not so good. ZYME is valued quite expensively, but it does show have an excellent growth rating.


Dividend Valuation Growth Profitability Health

Quickly go to:

1

1. Profitability

1.1 Basic Checks

ZYME had negative earnings in the past year.
ZYME had a negative operating cash flow in the past year.
ZYME had negative earnings in 4 of the past 5 years.
In the past 5 years ZYME reported 4 times negative operating cash flow.
ZYME Yearly Net Income VS EBIT VS OCF VS FCFZYME Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 100M -100M -200M

1.2 Ratios

ZYME's Return On Assets of -15.97% is fine compared to the rest of the industry. ZYME outperforms 79.40% of its industry peers.
ZYME's Return On Equity of -19.82% is amongst the best of the industry. ZYME outperforms 83.36% of its industry peers.
Industry RankSector Rank
ROA -15.97%
ROE -19.82%
ROIC N/A
ROA(3y)-9.25%
ROA(5y)-23.15%
ROE(3y)-12.18%
ROE(5y)-33.12%
ROIC(3y)N/A
ROIC(5y)N/A
ZYME Yearly ROA, ROE, ROICZYME Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 20 -20 -40 -60 -80 -100

1.3 Margins

The Profit Margin and Operating Margin and Gross Margin are not available for ZYME so they could not be analyzed.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM N/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
ZYME Yearly Profit, Operating, Gross MarginsZYME Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -200 -400 -600 -800

More info and screens

8

2. Health

2.1 Basic Checks

ZYME does not have a ROIC to compare to the WACC, probably because it is not profitable.
ZYME has less shares outstanding than it did 1 year ago.
ZYME has more shares outstanding than it did 5 years ago.
Compared to 1 year ago, ZYME has an improved debt to assets ratio.
ZYME Yearly Shares OutstandingZYME Yearly Shares OutstandingYearly Shares Outstanding 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 20M 40M 60M
ZYME Yearly Total Debt VS Total AssetsZYME Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 200M 400M 600M

2.2 Solvency

An Altman-Z score of 12.74 indicates that ZYME is not in any danger for bankruptcy at the moment.
ZYME has a better Altman-Z score (12.74) than 84.88% of its industry peers.
ZYME has no outstanding debt. Therefor its Debt/Equity and Debt/FCF ratios are 0 and belong to the best of the industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z 12.74
ROIC/WACCN/A
WACC8.8%
ZYME Yearly LT Debt VS Equity VS FCFZYME Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 200M -200M 400M

2.3 Liquidity

ZYME has a Current Ratio of 6.94. This indicates that ZYME is financially healthy and has no problem in meeting its short term obligations.
Looking at the Current ratio, with a value of 6.94, ZYME is in the better half of the industry, outperforming 69.57% of the companies in the same industry.
ZYME has a Quick Ratio of 6.94. This indicates that ZYME is financially healthy and has no problem in meeting its short term obligations.
ZYME's Quick ratio of 6.94 is fine compared to the rest of the industry. ZYME outperforms 69.94% of its industry peers.
Industry RankSector Rank
Current Ratio 6.94
Quick Ratio 6.94
ZYME Yearly Current Assets VS Current LiabilitesZYME Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 100M 200M 300M 400M 500M

More info and screens

7

3. Growth

3.1 Past

ZYME shows a strong growth in Earnings Per Share. In the last year, the EPS has been growing by 34.37%, which is quite impressive.
The Revenue has grown by 116.21% in the past year. This is a very strong growth!
ZYME shows a strong growth in Revenue. Measured over the last years, the Revenue has been growing by 20.93% yearly.
EPS 1Y (TTM)34.37%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%33.33%
Revenue 1Y (TTM)116.21%
Revenue growth 3Y41.91%
Revenue growth 5Y20.93%
Sales Q2Q%72.59%

3.2 Future

The Earnings Per Share is expected to grow by 17.53% on average over the next years. This is quite good.
The Revenue is expected to grow by 33.10% on average over the next years. This is a very strong growth
EPS Next Y25.66%
EPS Next 2Y25.81%
EPS Next 3Y-1.62%
EPS Next 5Y17.53%
Revenue Next Year35.83%
Revenue Next 2Y50.63%
Revenue Next 3Y29.86%
Revenue Next 5Y33.1%

3.3 Evolution

When comparing the Revenue growth rate of the last years to the growth rate of the upcoming years, we see that the growth is accelerating.
ZYME Yearly Revenue VS EstimatesZYME Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2014 2016 2018 2020 2022 2024 2026 2028 2030 2032 200M 400M 600M 800M 1B
ZYME Yearly EPS VS EstimatesZYME Yearly EPS VS EstimatesYearly EPS VS Estimates 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 0 2 -2 -4

More info and screens

0

4. Valuation

4.1 Price/Earnings Ratio

The Price/Earnings Ratio is negative for ZYME. In the last year negative earnings were reported.
Besides the negative Price/Earnings Ratio, also the Forward Price/Earnings Ratio is negative for ZYME. No positive earnings are expected for the next year.
Industry RankSector Rank
PE N/A
Fwd PE N/A
ZYME Price Earnings VS Forward Price EarningsZYME Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 20 -20 40 -40 60

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
ZYME Per share dataZYME EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 1 2 3 4

4.3 Compensation for Growth

PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y25.81%
EPS Next 3Y-1.62%

More info and screens

0

5. Dividend

5.1 Amount

ZYME does not give a dividend.
Industry RankSector Rank
Dividend Yield 0%

More info and screens

ZYMEWORKS INC

NASDAQ:ZYME (12/19/2025, 8:22:48 PM)

After market: 27.32 +0.09 (+0.33%)

27.23

+0.83 (+3.14%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)11-06 2025-11-06/amc
Earnings (Next)03-03 2026-03-03/amc
Inst Owners97.16%
Inst Owner Change-2.37%
Ins Owners0.7%
Ins Owner Change10.39%
Market Cap2.04B
Revenue(TTM)134.48M
Net Income(TTM)-63.43M
Analysts84.44
Price Target35.19 (29.23%)
Short Float %7.78%
Short Ratio4.42
Dividend
Industry RankSector Rank
Dividend Yield 0%
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)2
Avg EPS beat(2)63.29%
Min EPS beat(2)20.62%
Max EPS beat(2)105.95%
EPS beat(4)3
Avg EPS beat(4)-13.1%
Min EPS beat(4)-206.99%
Max EPS beat(4)105.95%
EPS beat(8)6
Avg EPS beat(8)-2.48%
EPS beat(12)8
Avg EPS beat(12)-2.95%
EPS beat(16)12
Avg EPS beat(16)3.95%
Revenue beat(2)1
Avg Revenue beat(2)69.22%
Min Revenue beat(2)-8.1%
Max Revenue beat(2)146.55%
Revenue beat(4)2
Avg Revenue beat(4)33.61%
Min Revenue beat(4)-32.69%
Max Revenue beat(4)146.55%
Revenue beat(8)4
Avg Revenue beat(8)11.83%
Revenue beat(12)7
Avg Revenue beat(12)16.19%
Revenue beat(16)8
Avg Revenue beat(16)13.31%
PT rev (1m)39.39%
PT rev (3m)56.42%
EPS NQ rev (1m)-86.3%
EPS NQ rev (3m)-106.97%
EPS NY rev (1m)-16.92%
EPS NY rev (3m)-6.07%
Revenue NQ rev (1m)-55.48%
Revenue NQ rev (3m)-61.77%
Revenue NY rev (1m)-17.6%
Revenue NY rev (3m)-20.85%
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S 15.15
P/FCF N/A
P/OCF N/A
P/B 6.37
P/tB 6.65
EV/EBITDA N/A
EPS(TTM)-0.84
EYN/A
EPS(NY)-0.58
Fwd EYN/A
FCF(TTM)-0.88
FCFYN/A
OCF(TTM)-0.86
OCFYN/A
SpS1.8
BVpS4.28
TBVpS4.1
PEG (NY)N/A
PEG (5Y)N/A
Graham NumberN/A
Profitability
Industry RankSector Rank
ROA -15.97%
ROE -19.82%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM N/A
FCFM N/A
ROA(3y)-9.25%
ROA(5y)-23.15%
ROE(3y)-12.18%
ROE(5y)-33.12%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score6
Asset Turnover0.34
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 24.88%
Cap/Sales 1.45%
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 6.94
Quick Ratio 6.94
Altman-Z 12.74
F-Score6
WACC8.8%
ROIC/WACCN/A
Cap/Depr(3y)85.79%
Cap/Depr(5y)108.98%
Cap/Sales(3y)4.19%
Cap/Sales(5y)15.7%
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)34.37%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%33.33%
EPS Next Y25.66%
EPS Next 2Y25.81%
EPS Next 3Y-1.62%
EPS Next 5Y17.53%
Revenue 1Y (TTM)116.21%
Revenue growth 3Y41.91%
Revenue growth 5Y20.93%
Sales Q2Q%72.59%
Revenue Next Year35.83%
Revenue Next 2Y50.63%
Revenue Next 3Y29.86%
Revenue Next 5Y33.1%
EBIT growth 1Y41.94%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year58.33%
EBIT Next 3Y35.99%
EBIT Next 5YN/A
FCF growth 1Y-134.5%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y-132.93%
OCF growth 3YN/A
OCF growth 5YN/A

ZYMEWORKS INC / ZYME FAQ

What is the ChartMill fundamental rating of ZYMEWORKS INC (ZYME) stock?

ChartMill assigns a fundamental rating of 4 / 10 to ZYME.


What is the valuation status for ZYME stock?

ChartMill assigns a valuation rating of 0 / 10 to ZYMEWORKS INC (ZYME). This can be considered as Overvalued.


Can you provide the profitability details for ZYMEWORKS INC?

ZYMEWORKS INC (ZYME) has a profitability rating of 1 / 10.


What is the expected EPS growth for ZYMEWORKS INC (ZYME) stock?

The Earnings per Share (EPS) of ZYMEWORKS INC (ZYME) is expected to grow by 25.66% in the next year.