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ZYMEWORKS INC (ZYME) Stock Fundamental Analysis

USA - NASDAQ:ZYME - US98985Y1082 - Common Stock

17.93 USD
-0.39 (-2.13%)
Last: 10/21/2025, 8:00:02 PM
17.93 USD
0 (0%)
After Hours: 10/21/2025, 8:00:02 PM
Fundamental Rating

4

Overall ZYME gets a fundamental rating of 4 out of 10. We evaluated ZYME against 534 industry peers in the Biotechnology industry. ZYME has a great financial health rating, but its profitability evaluates not so good. ZYME is quite expensive at the moment. It does show a decent growth rate.


Dividend Valuation Growth Profitability Health

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1

1. Profitability

1.1 Basic Checks

In the past year ZYME has reported negative net income.
ZYME had a negative operating cash flow in the past year.
ZYME had negative earnings in 4 of the past 5 years.
ZYME had negative operating cash flow in 4 of the past 5 years.
ZYME Yearly Net Income VS EBIT VS OCF VS FCFZYME Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 100M -100M -200M

1.2 Ratios

With a decent Return On Assets value of -18.04%, ZYME is doing good in the industry, outperforming 78.84% of the companies in the same industry.
ZYME's Return On Equity of -22.03% is amongst the best of the industry. ZYME outperforms 83.15% of its industry peers.
Industry RankSector Rank
ROA -18.04%
ROE -22.03%
ROIC N/A
ROA(3y)-9.25%
ROA(5y)-23.15%
ROE(3y)-12.18%
ROE(5y)-33.12%
ROIC(3y)N/A
ROIC(5y)N/A
ZYME Yearly ROA, ROE, ROICZYME Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 20 -20 -40 -60 -80 -100

1.3 Margins

ZYME does not have Profit Margin and Operating Margin and Gross Margin available, so we won't be analyzing them here.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM N/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
ZYME Yearly Profit, Operating, Gross MarginsZYME Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -200 -400 -600 -800

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8

2. Health

2.1 Basic Checks

ZYME does not have a ROIC to compare to the WACC, probably because it is not profitable.
ZYME has less shares outstanding than it did 1 year ago.
Compared to 5 years ago, ZYME has more shares outstanding
Compared to 1 year ago, ZYME has an improved debt to assets ratio.
ZYME Yearly Shares OutstandingZYME Yearly Shares OutstandingYearly Shares Outstanding 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 20M 40M 60M
ZYME Yearly Total Debt VS Total AssetsZYME Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 200M 400M 600M

2.2 Solvency

An Altman-Z score of 8.66 indicates that ZYME is not in any danger for bankruptcy at the moment.
ZYME has a Altman-Z score of 8.66. This is amongst the best in the industry. ZYME outperforms 81.09% of its industry peers.
ZYME has no outstanding debt. Therefor its Debt/Equity and Debt/FCF ratios are 0 and belong to the best of the industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z 8.66
ROIC/WACCN/A
WACC9.35%
ZYME Yearly LT Debt VS Equity VS FCFZYME Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 200M -200M 400M

2.3 Liquidity

A Current Ratio of 7.69 indicates that ZYME has no problem at all paying its short term obligations.
ZYME has a better Current ratio (7.69) than 72.66% of its industry peers.
ZYME has a Quick Ratio of 7.69. This indicates that ZYME is financially healthy and has no problem in meeting its short term obligations.
ZYME has a better Quick ratio (7.69) than 73.03% of its industry peers.
Industry RankSector Rank
Current Ratio 7.69
Quick Ratio 7.69
ZYME Yearly Current Assets VS Current LiabilitesZYME Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 100M 200M 300M 400M 500M

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5

3. Growth

3.1 Past

The Earnings Per Share has grown by an impressive 25.38% over the past year.
Looking at the last year, ZYME shows a very strong growth in Revenue. The Revenue has grown by 95.96%.
ZYME shows a strong growth in Revenue. Measured over the last years, the Revenue has been growing by 20.93% yearly.
EPS 1Y (TTM)25.38%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%111.11%
Revenue 1Y (TTM)95.96%
Revenue growth 3Y41.91%
Revenue growth 5Y20.93%
Sales Q2Q%153.21%

3.2 Future

ZYME is expected to show a very negative growth in Earnings Per Share. In the coming years, the EPS will decrease by -12.90% yearly.
The Revenue is expected to grow by 19.82% on average over the next years. This is quite good.
EPS Next Y36.89%
EPS Next 2Y1.68%
EPS Next 3Y-6.84%
EPS Next 5Y-12.9%
Revenue Next Year71.6%
Revenue Next 2Y32.53%
Revenue Next 3Y13.93%
Revenue Next 5Y19.82%

3.3 Evolution

When comparing the Revenue growth rate of the last years to the growth rate of the upcoming years, we see that the growth is stable.
ZYME Yearly Revenue VS EstimatesZYME Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2014 2016 2018 2020 2022 2024 2026 2028 2030 2032 100M 200M 300M 400M
ZYME Yearly EPS VS EstimatesZYME Yearly EPS VS EstimatesYearly EPS VS Estimates 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 0 -2 -4

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0

4. Valuation

4.1 Price/Earnings Ratio

The Price/Earnings Ratio is negative for ZYME. In the last year negative earnings were reported.
Besides the negative Price/Earnings Ratio, also the Forward Price/Earnings Ratio is negative for ZYME. No positive earnings are expected for the next year.
Industry RankSector Rank
PE N/A
Fwd PE N/A
ZYME Price Earnings VS Forward Price EarningsZYME Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 20 40 60

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
ZYME Per share dataZYME EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 1 -1 2 3 4

4.3 Compensation for Growth

ZYME's earnings are expected to decrease with -6.84% in the coming years. This may justify a cheaper valuation.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y1.68%
EPS Next 3Y-6.84%

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0

5. Dividend

5.1 Amount

ZYME does not give a dividend.
Industry RankSector Rank
Dividend Yield N/A

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ZYMEWORKS INC

NASDAQ:ZYME (10/21/2025, 8:00:02 PM)

After market: 17.93 0 (0%)

17.93

-0.39 (-2.13%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)08-07 2025-08-07/amc
Earnings (Next)11-06 2025-11-06
Inst Owners99.82%
Inst Owner Change1.06%
Ins Owners0.69%
Ins Owner Change10.39%
Market Cap1.35B
Analysts83.75
Price Target22.5 (25.49%)
Short Float %9.77%
Short Ratio14.91
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)2
Avg EPS beat(2)66.98%
Min EPS beat(2)28.01%
Max EPS beat(2)105.95%
EPS beat(4)3
Avg EPS beat(4)-17.42%
Min EPS beat(4)-206.99%
Max EPS beat(4)105.95%
EPS beat(8)6
Avg EPS beat(8)-3.26%
EPS beat(12)8
Avg EPS beat(12)-2.73%
EPS beat(16)12
Avg EPS beat(16)2.77%
Revenue beat(2)2
Avg Revenue beat(2)87.62%
Min Revenue beat(2)28.69%
Max Revenue beat(2)146.55%
Revenue beat(4)3
Avg Revenue beat(4)36.26%
Min Revenue beat(4)-32.69%
Max Revenue beat(4)146.55%
Revenue beat(8)5
Avg Revenue beat(8)20.24%
Revenue beat(12)7
Avg Revenue beat(12)13.88%
Revenue beat(16)8
Avg Revenue beat(16)11.24%
PT rev (1m)0%
PT rev (3m)-1.49%
EPS NQ rev (1m)-0.85%
EPS NQ rev (3m)10.29%
EPS NY rev (1m)9.95%
EPS NY rev (3m)44.42%
Revenue NQ rev (1m)-13.64%
Revenue NQ rev (3m)4.68%
Revenue NY rev (1m)0%
Revenue NY rev (3m)43.57%
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S 10.97
P/FCF N/A
P/OCF N/A
P/B 4.03
P/tB 4.21
EV/EBITDA N/A
EPS(TTM)-0.97
EYN/A
EPS(NY)-1.34
Fwd EYN/A
FCF(TTM)-0.54
FCFYN/A
OCF(TTM)-0.51
OCFYN/A
SpS1.63
BVpS4.45
TBVpS4.26
PEG (NY)N/A
PEG (5Y)N/A
Profitability
Industry RankSector Rank
ROA -18.04%
ROE -22.03%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM N/A
FCFM N/A
ROA(3y)-9.25%
ROA(5y)-23.15%
ROE(3y)-12.18%
ROE(5y)-33.12%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexcg growth 3YN/A
ROICexcg growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score7
Asset Turnover0.3
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 25.13%
Cap/Sales 2.07%
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 7.69
Quick Ratio 7.69
Altman-Z 8.66
F-Score7
WACC9.35%
ROIC/WACCN/A
Cap/Depr(3y)85.79%
Cap/Depr(5y)108.98%
Cap/Sales(3y)4.19%
Cap/Sales(5y)15.7%
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)25.38%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%111.11%
EPS Next Y36.89%
EPS Next 2Y1.68%
EPS Next 3Y-6.84%
EPS Next 5Y-12.9%
Revenue 1Y (TTM)95.96%
Revenue growth 3Y41.91%
Revenue growth 5Y20.93%
Sales Q2Q%153.21%
Revenue Next Year71.6%
Revenue Next 2Y32.53%
Revenue Next 3Y13.93%
Revenue Next 5Y19.82%
EBIT growth 1Y31.43%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year71.7%
EBIT Next 3Y-6.87%
EBIT Next 5YN/A
FCF growth 1Y-125.75%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y-123.3%
OCF growth 3YN/A
OCF growth 5YN/A