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TWIST BIOSCIENCE CORP (TWST) Stock Fundamental Analysis

USA - Nasdaq - NASDAQ:TWST - US90184D1000 - Common Stock

30.93 USD
-1.19 (-3.7%)
Last: 12/12/2025, 8:05:36 PM
30.75 USD
-0.18 (-0.58%)
After Hours: 12/12/2025, 8:05:36 PM
Fundamental Rating

4

Overall TWST gets a fundamental rating of 4 out of 10. We evaluated TWST against 529 industry peers in the Biotechnology industry. While TWST has a great health rating, there are worries on its profitability. While showing a medium growth rate, TWST is valued expensive at the moment.


Dividend Valuation Growth Profitability Health

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3

1. Profitability

1.1 Basic Checks

In the past year TWST has reported negative net income.
TWST had a negative operating cash flow in the past year.
In the past 5 years TWST always reported negative net income.
In the past 5 years TWST always reported negative operating cash flow.
TWST Yearly Net Income VS EBIT VS OCF VS FCFTWST Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 -50M -100M -150M -200M

1.2 Ratios

Looking at the Return On Assets, with a value of -12.10%, TWST belongs to the top of the industry, outperforming 82.49% of the companies in the same industry.
With an excellent Return On Equity value of -16.42%, TWST belongs to the best of the industry, outperforming 85.12% of the companies in the same industry.
Industry RankSector Rank
ROA -12.1%
ROE -16.42%
ROIC N/A
ROA(3y)-24.14%
ROA(5y)-23.35%
ROE(3y)-31.13%
ROE(5y)-29.44%
ROIC(3y)N/A
ROIC(5y)N/A
TWST Yearly ROA, ROE, ROICTWST Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 20 -20 40 -40 -60

1.3 Margins

With a decent Gross Margin value of 50.72%, TWST is doing good in the industry, outperforming 76.08% of the companies in the same industry.
In the last couple of years the Gross Margin of TWST has grown nicely.
TWST does not have Profit Margin and Operating Margin available, so we won't be analyzing them here.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM 50.72%
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3Y7.04%
GM growth 5Y9.75%
TWST Yearly Profit, Operating, Gross MarginsTWST Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 -500 -1K -1.5K

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7

2. Health

2.1 Basic Checks

TWST does not have a ROIC to compare to the WACC, probably because it is not profitable.
Compared to 1 year ago, TWST has more shares outstanding
The number of shares outstanding for TWST has been increased compared to 5 years ago.
There is no outstanding debt for TWST. This means it has a Debt/Equity and Debt/FCF ratio of 0 and it is amongst the best of the sector and industry.
TWST Yearly Shares OutstandingTWST Yearly Shares OutstandingYearly Shares Outstanding 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 20M 40M 60M
TWST Yearly Total Debt VS Total AssetsTWST Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 200M 400M 600M 800M

2.2 Solvency

TWST has an Altman-Z score of 4.18. This indicates that TWST is financially healthy and has little risk of bankruptcy at the moment.
TWST has a better Altman-Z score (4.18) than 70.06% of its industry peers.
There is no outstanding debt for TWST. This means it has a Debt/Equity and Debt/FCF ratio of 0 and it is amongst the best of the sector and industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z 4.18
ROIC/WACCN/A
WACC8.83%
TWST Yearly LT Debt VS Equity VS FCFTWST Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 200M -200M 400M 600M

2.3 Liquidity

A Current Ratio of 3.64 indicates that TWST has no problem at all paying its short term obligations.
TWST has a Current ratio (3.64) which is in line with its industry peers.
TWST has a Quick Ratio of 3.33. This indicates that TWST is financially healthy and has no problem in meeting its short term obligations.
With a Quick ratio value of 3.33, TWST perfoms like the industry average, outperforming 41.81% of the companies in the same industry.
Industry RankSector Rank
Current Ratio 3.64
Quick Ratio 3.33
TWST Yearly Current Assets VS Current LiabilitesTWST Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 100M 200M 300M 400M 500M

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6

3. Growth

3.1 Past

TWST shows a strong growth in Earnings Per Share. In the last year, the EPS has been growing by 41.39%, which is quite impressive.
The Revenue has grown by 20.32% in the past year. This is a very strong growth!
The Revenue has been growing by 33.11% on average over the past years. This is a very strong growth!
EPS 1Y (TTM)41.39%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%23.73%
Revenue 1Y (TTM)20.32%
Revenue growth 3Y22.75%
Revenue growth 5Y33.11%
Sales Q2Q%16.88%

3.2 Future

Based on estimates for the next years, TWST will show a very strong growth in Earnings Per Share. The EPS will grow by 20.98% on average per year.
The Revenue is expected to grow by 16.03% on average over the next years. This is quite good.
EPS Next Y27.1%
EPS Next 2Y21.25%
EPS Next 3Y20.98%
EPS Next 5YN/A
Revenue Next Year13.49%
Revenue Next 2Y14.29%
Revenue Next 3Y15.4%
Revenue Next 5Y16.03%

3.3 Evolution

Although the future Revenue growth is still strong, it is not able to hold up the even more excellent growth rate of the past years.
TWST Yearly Revenue VS EstimatesTWST Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 200M 400M 600M 800M
TWST Yearly EPS VS EstimatesTWST Yearly EPS VS EstimatesYearly EPS VS Estimates 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 -1 -2 -3 -4

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1

4. Valuation

4.1 Price/Earnings Ratio

TWST reported negative earnings for the last year, which makes the Price/Earnings Ratio negative.
Also next year TWST is expected to report negative earnings again, which makes the also the Forward Price/Earnings Ratio negative.
Industry RankSector Rank
PE N/A
Fwd PE N/A
TWST Price Earnings VS Forward Price EarningsTWST Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 20 -20 40 60

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
TWST Per share dataTWST EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 2 -2 4 6

4.3 Compensation for Growth

A more expensive valuation may be justified as TWST's earnings are expected to grow with 20.98% in the coming years.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y21.25%
EPS Next 3Y20.98%

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0

5. Dividend

5.1 Amount

No dividends for TWST!.
Industry RankSector Rank
Dividend Yield 0%

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TWIST BIOSCIENCE CORP

NASDAQ:TWST (12/12/2025, 8:05:36 PM)

After market: 30.75 -0.18 (-0.58%)

30.93

-1.19 (-3.7%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)11-14 2025-11-14/bmo
Earnings (Next)02-02 2026-02-02
Inst Owners119.79%
Inst Owner Change5.35%
Ins Owners2.09%
Ins Owner Change7.14%
Market Cap1.89B
Revenue(TTM)376.57M
Net Income(TTM)-77.67M
Analysts84.71
Price Target39.29 (27.03%)
Short Float %18.32%
Short Ratio6.09
Dividend
Industry RankSector Rank
Dividend Yield 0%
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)1
Avg EPS beat(2)7.37%
Min EPS beat(2)-2.79%
Max EPS beat(2)17.53%
EPS beat(4)2
Avg EPS beat(4)5.13%
Min EPS beat(4)-12.39%
Max EPS beat(4)18.15%
EPS beat(8)5
Avg EPS beat(8)-4.84%
EPS beat(12)9
Avg EPS beat(12)4.41%
EPS beat(16)13
Avg EPS beat(16)8.12%
Revenue beat(2)0
Avg Revenue beat(2)-0.88%
Min Revenue beat(2)-1.51%
Max Revenue beat(2)-0.26%
Revenue beat(4)1
Avg Revenue beat(4)-0.72%
Min Revenue beat(4)-1.51%
Max Revenue beat(4)0%
Revenue beat(8)5
Avg Revenue beat(8)1.19%
Revenue beat(12)8
Avg Revenue beat(12)1.55%
Revenue beat(16)11
Avg Revenue beat(16)2.24%
PT rev (1m)-9.29%
PT rev (3m)-13.8%
EPS NQ rev (1m)-7.41%
EPS NQ rev (3m)-4.66%
EPS NY rev (1m)0.52%
EPS NY rev (3m)-12.12%
Revenue NQ rev (1m)0.03%
Revenue NQ rev (3m)-0.75%
Revenue NY rev (1m)-2.3%
Revenue NY rev (3m)-3.23%
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S 5.02
P/FCF N/A
P/OCF N/A
P/B 4
P/tB 5.01
EV/EBITDA N/A
EPS(TTM)-2.11
EYN/A
EPS(NY)-1.54
Fwd EYN/A
FCF(TTM)-1.24
FCFYN/A
OCF(TTM)-0.78
OCFYN/A
SpS6.16
BVpS7.73
TBVpS6.17
PEG (NY)N/A
PEG (5Y)N/A
Graham NumberN/A
Profitability
Industry RankSector Rank
ROA -12.1%
ROE -16.42%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM 50.72%
FCFM N/A
ROA(3y)-24.14%
ROA(5y)-23.35%
ROE(3y)-31.13%
ROE(5y)-29.44%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3Y7.04%
GM growth 5Y9.75%
F-Score5
Asset Turnover0.59
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 112.68%
Cap/Sales 7.44%
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 3.64
Quick Ratio 3.33
Altman-Z 4.18
F-Score5
WACC8.83%
ROIC/WACCN/A
Cap/Depr(3y)74.54%
Cap/Depr(5y)223.62%
Cap/Sales(3y)6.8%
Cap/Sales(5y)18.18%
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)41.39%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%23.73%
EPS Next Y27.1%
EPS Next 2Y21.25%
EPS Next 3Y20.98%
EPS Next 5YN/A
Revenue 1Y (TTM)20.32%
Revenue growth 3Y22.75%
Revenue growth 5Y33.11%
Sales Q2Q%16.88%
Revenue Next Year13.49%
Revenue Next 2Y14.29%
Revenue Next 3Y15.4%
Revenue Next 5Y16.03%
EBIT growth 1Y22.54%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year74.55%
EBIT Next 3Y28.07%
EBIT Next 5Y22.99%
FCF growth 1Y-9.34%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y25.69%
OCF growth 3YN/A
OCF growth 5YN/A

TWIST BIOSCIENCE CORP / TWST FAQ

Can you provide the ChartMill fundamental rating for TWIST BIOSCIENCE CORP?

ChartMill assigns a fundamental rating of 4 / 10 to TWST.


What is the valuation status of TWIST BIOSCIENCE CORP (TWST) stock?

ChartMill assigns a valuation rating of 1 / 10 to TWIST BIOSCIENCE CORP (TWST). This can be considered as Overvalued.


How profitable is TWIST BIOSCIENCE CORP (TWST) stock?

TWIST BIOSCIENCE CORP (TWST) has a profitability rating of 3 / 10.


What is the earnings growth outlook for TWIST BIOSCIENCE CORP?

The Earnings per Share (EPS) of TWIST BIOSCIENCE CORP (TWST) is expected to grow by 27.1% in the next year.