SYNLOGIC INC (SYBX) Stock Fundamental Analysis

NASDAQ:SYBX • US87166L2097

0.56 USD
-0.56 (-50%)
At close: Jan 20, 2026
0.5753 USD
+0.02 (+2.73%)
After Hours: 1/20/2026, 8:21:57 PM
Overview Stock Chart Technical Analysis Fundamental Analysis Analyst Ratings Earnings Estimates Financials Ownership News
Fundamental Rating

2

We assign a fundamental rating of 2 out of 10 to SYBX. SYBX was compared to 520 industry peers in the Biotechnology industry. While SYBX seems to be doing ok healthwise, there are quite some concerns on its profitability. SYBX does not seem to be growing, but still is valued expensively.


Dividend Valuation Growth Profitability Health

1

1. Profitability

1.1 Basic Checks

  • In the past year SYBX has reported negative net income.
  • SYBX had a negative operating cash flow in the past year.
  • In the past 5 years SYBX always reported negative net income.
  • SYBX had a negative operating cash flow in each of the past 5 years.
SYBX Yearly Net Income VS EBIT VS OCF VS FCFSYBX Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2016 2017 2018 2019 2020 2021 2022 2023 2024 -20M -40M -60M

1.2 Ratios

  • With a decent Return On Assets value of -19.49%, SYBX is doing good in the industry, outperforming 76.76% of the companies in the same industry.
  • SYBX has a better Return On Equity (-31.25%) than 75.24% of its industry peers.
Industry RankSector Rank
ROA -19.49%
ROE -31.25%
ROIC N/A
ROA(3y)-86.19%
ROA(5y)-66.88%
ROE(3y)-150.08%
ROE(5y)-108.55%
ROIC(3y)N/A
ROIC(5y)N/A
SYBX Yearly ROA, ROE, ROICSYBX Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2016 2017 2018 2019 2020 2021 2022 2023 2024 -50 -100 -150

1.3 Margins

  • SYBX does not have Profit Margin and Operating Margin and Gross Margin available, so we won't be analyzing them here.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM N/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
SYBX Yearly Profit, Operating, Gross MarginsSYBX Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2016 2017 2018 2019 2020 2021 2022 2023 2024 -50K -100K -150K -200K -250K

More info and screens

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5

2. Health

2.1 Basic Checks

  • SYBX does not have a ROIC to compare to the WACC, probably because it is not profitable.
  • The number of shares outstanding for SYBX has been increased compared to 1 year ago.
  • SYBX has more shares outstanding than it did 5 years ago.
  • SYBX has no outstanding debt. Therefor its Debt/Equity and Debt/FCF ratios are 0 and belong to the best of the industry.
SYBX Yearly Shares OutstandingSYBX Yearly Shares OutstandingYearly Shares Outstanding 2016 2017 2018 2019 2020 2021 2022 2023 2024 2M 4M 6M 8M 10M
SYBX Yearly Total Debt VS Total AssetsSYBX Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2016 2017 2018 2019 2020 2021 2022 2023 2024 50M 100M 150M

2.2 Solvency

  • SYBX has an Altman-Z score of -36.96. This is a bad value and indicates that SYBX is not financially healthy and even has some risk of bankruptcy.
  • Looking at the Altman-Z score, with a value of -36.96, SYBX is doing worse than 89.71% of the companies in the same industry.
  • There is no outstanding debt for SYBX. This means it has a Debt/Equity and Debt/FCF ratio of 0 and it is amongst the best of the sector and industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z -36.96
ROIC/WACCN/A
WACC8.9%
SYBX Yearly LT Debt VS Equity VS FCFSYBX Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 50M -50M 100M 150M

2.3 Liquidity

  • A Current Ratio of 2.65 indicates that SYBX has no problem at all paying its short term obligations.
  • SYBX has a Current ratio of 2.65. This is in the lower half of the industry: SYBX underperforms 69.14% of its industry peers.
  • A Quick Ratio of 2.65 indicates that SYBX has no problem at all paying its short term obligations.
  • SYBX has a worse Quick ratio (2.65) than 67.24% of its industry peers.
Industry RankSector Rank
Current Ratio 2.65
Quick Ratio 2.65
SYBX Yearly Current Assets VS Current LiabilitesSYBX Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2016 2017 2018 2019 2020 2021 2022 2023 2024 20M 40M 60M 80M 100M

More info and screens

WACCDebt/EquityHow to determine the health of a companyAltman-Z scoreShow peers with great health

1

3. Growth

3.1 Past

  • The Earnings Per Share has grown by an impressive 76.93% over the past year.
  • SYBX shows a very negative growth in Revenue. In the last year, the Revenue has decreased by -100.00%.
  • Measured over the past years, SYBX shows a very negative growth in Revenue. The Revenue has been decreasing by -67.54% on average per year.
EPS 1Y (TTM)76.93%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-1845.83%
Revenue 1Y (TTM)-100%
Revenue growth 3Y-83.4%
Revenue growth 5Y-67.54%
Sales Q2Q%N/A

3.2 Future

  • SYBX is expected to show a strong growth in Earnings Per Share. In the coming years, the EPS will grow by 48.51% yearly.
  • No Revenue estimates are available, so we could not analyze the future revenue growth and evolution.
EPS Next Y80.9%
EPS Next 2Y38.08%
EPS Next 3Y-10.72%
EPS Next 5Y48.51%
Revenue Next YearN/A
Revenue Next 2YN/A
Revenue Next 3YN/A
Revenue Next 5YN/A

3.3 Evolution

  • No Revenue estimates are available, so we could not analyze the future revenue growth and evolution.
SYBX Yearly Revenue VS EstimatesSYBX Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2016 2017 2018 2019 2020 2021 2022 2023 2024 2027 2028 50M 100M 150M 200M
SYBX Yearly EPS VS EstimatesSYBX Yearly EPS VS EstimatesYearly EPS VS Estimates 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 0 -100 -200 -300

More info and screens

Find the best growth stocksShow best growing peers

0

4. Valuation

4.1 Price/Earnings Ratio

  • The Price/Earnings Ratio is negative for SYBX. In the last year negative earnings were reported.
  • Besides the negative Price/Earnings Ratio, also the Forward Price/Earnings Ratio is negative for SYBX. No positive earnings are expected for the next year.
Industry RankSector Rank
PE N/A
Fwd PE N/A
SYBX Price Earnings VS Forward Price EarningsSYBX Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 20 40 60

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
SYBX Per share dataSYBX EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 -1 -2

4.3 Compensation for Growth

  • SYBX's earnings are expected to decrease with -10.72% in the coming years. This may justify a cheaper valuation.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y38.08%
EPS Next 3Y-10.72%

More info and screens

Price/EarningsPrice/FCFFCF per shareEV/EBITDAPEG RATIOShow best valued peers

0

5. Dividend

5.1 Amount

  • SYBX does not give a dividend.
Industry RankSector Rank
Dividend Yield 0%

More info and screens

Find the best dividend stocksShow peers with best dividend

SYNLOGIC INC

NASDAQ:SYBX (1/20/2026, 8:21:57 PM)

After market: 0.5753 +0.02 (+2.73%)

0.56

-0.56 (-50%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)11-13
Earnings (Next)03-04
Inst Owners63.65%
Inst Owner Change3.37%
Ins Owners11.06%
Ins Owner Change0%
Market Cap6.55M
Revenue(TTM)N/A
Net Income(TTM)-3.23M
Analysts43.33
Price Target1.02 (82.14%)
Short Float %0.34%
Short Ratio0.3
Dividend
Industry RankSector Rank
Dividend Yield 0%
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)N/A
Avg EPS beat(2)N/A
Min EPS beat(2)N/A
Max EPS beat(2)N/A
EPS beat(4)N/A
Avg EPS beat(4)N/A
Min EPS beat(4)N/A
Max EPS beat(4)N/A
EPS beat(8)N/A
Avg EPS beat(8)N/A
EPS beat(12)N/A
Avg EPS beat(12)N/A
EPS beat(16)N/A
Avg EPS beat(16)N/A
Revenue beat(2)N/A
Avg Revenue beat(2)N/A
Min Revenue beat(2)N/A
Max Revenue beat(2)N/A
Revenue beat(4)N/A
Avg Revenue beat(4)N/A
Min Revenue beat(4)N/A
Max Revenue beat(4)N/A
Revenue beat(8)N/A
Avg Revenue beat(8)N/A
Revenue beat(12)N/A
Avg Revenue beat(12)N/A
Revenue beat(16)N/A
Avg Revenue beat(16)N/A
PT rev (1m)0%
PT rev (3m)0%
EPS NQ rev (1m)0%
EPS NQ rev (3m)0%
EPS NY rev (1m)0%
EPS NY rev (3m)0%
Revenue NQ rev (1m)N/A
Revenue NQ rev (3m)N/A
Revenue NY rev (1m)N/A
Revenue NY rev (3m)N/A
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S N/A
P/FCF N/A
P/OCF N/A
P/B 0.63
P/tB 0.63
EV/EBITDA N/A
EPS(TTM)-2.51
EYN/A
EPS(NY)-0.23
Fwd EYN/A
FCF(TTM)-0.34
FCFYN/A
OCF(TTM)-0.34
OCFYN/A
SpS0
BVpS0.88
TBVpS0.88
PEG (NY)N/A
PEG (5Y)N/A
Graham NumberN/A
Profitability
Industry RankSector Rank
ROA -19.49%
ROE -31.25%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM N/A
FCFM N/A
ROA(3y)-86.19%
ROA(5y)-66.88%
ROE(3y)-150.08%
ROE(5y)-108.55%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score2
Asset Turnover0
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr N/A
Cap/Sales N/A
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 2.65
Quick Ratio 2.65
Altman-Z -36.96
F-Score2
WACC8.9%
ROIC/WACCN/A
Cap/Depr(3y)14.64%
Cap/Depr(5y)17.39%
Cap/Sales(3y)81.07%
Cap/Sales(5y)70.96%
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)76.93%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-1845.83%
EPS Next Y80.9%
EPS Next 2Y38.08%
EPS Next 3Y-10.72%
EPS Next 5Y48.51%
Revenue 1Y (TTM)-100%
Revenue growth 3Y-83.4%
Revenue growth 5Y-67.54%
Sales Q2Q%N/A
Revenue Next YearN/A
Revenue Next 2YN/A
Revenue Next 3YN/A
Revenue Next 5YN/A
EBIT growth 1Y89.14%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next YearN/A
EBIT Next 3YN/A
EBIT Next 5YN/A
FCF growth 1Y93.18%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y93.15%
OCF growth 3YN/A
OCF growth 5YN/A

SYNLOGIC INC / SYBX FAQ

What is the fundamental rating for SYBX stock?

ChartMill assigns a fundamental rating of 2 / 10 to SYBX.


What is the valuation status for SYBX stock?

ChartMill assigns a valuation rating of 0 / 10 to SYNLOGIC INC (SYBX). This can be considered as Overvalued.


How profitable is SYNLOGIC INC (SYBX) stock?

SYNLOGIC INC (SYBX) has a profitability rating of 1 / 10.


Can you provide the expected EPS growth for SYBX stock?

The Earnings per Share (EPS) of SYNLOGIC INC (SYBX) is expected to grow by 80.9% in the next year.