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SEPTERNA INC (SEPN) Stock Fundamental Analysis

USA - NASDAQ:SEPN - US81734D1046 - Common Stock

17.98 USD
-0.53 (-2.86%)
Last: 11/10/2025, 1:34:19 PM
Fundamental Rating

3

Taking everything into account, SEPN scores 3 out of 10 in our fundamental rating. SEPN was compared to 191 industry peers in the Pharmaceuticals industry. No worries on liquidiy or solvency for SEPN as it has an excellent financial health rating, but there are worries on the profitability. While showing a medium growth rate, SEPN is valued expensive at the moment.


Dividend Valuation Growth Profitability Health

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1

1. Profitability

1.1 Basic Checks

In the past year SEPN has reported negative net income.
In the past year SEPN has reported a negative cash flow from operations.
SEPN Yearly Net Income VS EBIT VS OCF VS FCFSEPN Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2022 2023 2024 0 -20M -40M -60M -80M

1.2 Ratios

SEPN has a better Return On Assets (-19.17%) than 60.73% of its industry peers.
SEPN's Return On Equity of -20.83% is fine compared to the rest of the industry. SEPN outperforms 67.02% of its industry peers.
Industry RankSector Rank
ROA -19.17%
ROE -20.83%
ROIC N/A
ROA(3y)-30.64%
ROA(5y)N/A
ROE(3y)-35.78%
ROE(5y)N/A
ROIC(3y)N/A
ROIC(5y)N/A
SEPN Yearly ROA, ROE, ROICSEPN Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2022 2023 2024 0 -20 -40 -60 -80

1.3 Margins

The Profit Margin and Operating Margin and Gross Margin are not available for SEPN so they could not be analyzed.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM N/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
SEPN Yearly Profit, Operating, Gross MarginsSEPN Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2022 2023 2024 0 -10K -20K -30K

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8

2. Health

2.1 Basic Checks

SEPN does not have a ROIC to compare to the WACC, probably because it is not profitable.
Compared to 1 year ago, SEPN has more shares outstanding
There is no outstanding debt for SEPN. This means it has a Debt/Equity and Debt/FCF ratio of 0 and it is amongst the best of the sector and industry.
SEPN Yearly Shares OutstandingSEPN Yearly Shares OutstandingYearly Shares Outstanding 2022 2023 2024 10M 20M 30M 40M
SEPN Yearly Total Debt VS Total AssetsSEPN Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2022 2023 2024 100M 200M 300M 400M

2.2 Solvency

SEPN has an Altman-Z score of 13.37. This indicates that SEPN is financially healthy and has little risk of bankruptcy at the moment.
The Altman-Z score of SEPN (13.37) is better than 86.91% of its industry peers.
SEPN has no outstanding debt. Therefor its Debt/Equity and Debt/FCF ratios are 0 and belong to the best of the industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z 13.37
ROIC/WACCN/A
WACC8.84%
SEPN Yearly LT Debt VS Equity VS FCFSEPN Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2022 2023 2024 0 100M 200M 300M 400M

2.3 Liquidity

SEPN has a Current Ratio of 27.77. This indicates that SEPN is financially healthy and has no problem in meeting its short term obligations.
The Current ratio of SEPN (27.77) is better than 97.38% of its industry peers.
SEPN has a Quick Ratio of 27.77. This indicates that SEPN is financially healthy and has no problem in meeting its short term obligations.
SEPN has a better Quick ratio (27.77) than 97.38% of its industry peers.
Industry RankSector Rank
Current Ratio 27.77
Quick Ratio 27.77
SEPN Yearly Current Assets VS Current LiabilitesSEPN Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2022 2023 2024 100M 200M 300M

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4

3. Growth

3.1 Past

SEPN shows a strong negative growth in Earnings Per Share. In the last year the EPS decreased by -53868.89%.
Looking at the last year, SEPN shows a very strong growth in Revenue. The Revenue has grown by 611.92%.
EPS 1Y (TTM)-53868.89%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%22.82%
Revenue 1Y (TTM)611.92%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%-82.68%

3.2 Future

Based on estimates for the next years, SEPN will show a quite strong growth in Earnings Per Share. The EPS will grow by 8.52% on average per year.
SEPN is expected to show a strong growth in Revenue. In the coming years, the Revenue will grow by 121.87% yearly.
EPS Next Y100.45%
EPS Next 2Y31.63%
EPS Next 3Y17.26%
EPS Next 5Y8.52%
Revenue Next Year10618.3%
Revenue Next 2Y666.69%
Revenue Next 3Y264.4%
Revenue Next 5Y121.87%

3.3 Evolution

SEPN Yearly Revenue VS EstimatesSEPN Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 100M 200M 300M 400M 500M
SEPN Yearly EPS VS EstimatesSEPN Yearly EPS VS EstimatesYearly EPS VS Estimates 2024 2025 2026 2027 2028 2029 2030 2031 2032 0 -2 -4 -6

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0

4. Valuation

4.1 Price/Earnings Ratio

SEPN reported negative earnings for the last year, which makes the Price/Earnings Ratio negative.
Also next year SEPN is expected to report negative earnings again, which makes the also the Forward Price/Earnings Ratio negative.
Industry RankSector Rank
PE N/A
Fwd PE N/A
SEPN Price Earnings VS Forward Price EarningsSEPN Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 10 20 30 40

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
SEPN Per share dataSEPN EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 5 -5 -10

4.3 Compensation for Growth

SEPN's earnings are expected to grow with 17.26% in the coming years. This may justify a more expensive valuation.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y31.63%
EPS Next 3Y17.26%

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0

5. Dividend

5.1 Amount

No dividends for SEPN!.
Industry RankSector Rank
Dividend Yield N/A

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SEPTERNA INC

NASDAQ:SEPN (11/10/2025, 1:34:19 PM)

17.98

-0.53 (-2.86%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryPharmaceuticals
Earnings (Last)08-11 2025-08-11/amc
Earnings (Next)11-19 2025-11-19
Inst Owners99.28%
Inst Owner Change0.18%
Ins Owners2.94%
Ins Owner Change0.43%
Market Cap801.73M
Revenue(TTM)726.00K
Net Income(TTM)-87.50M
Analysts80
Price Target23.46 (30.48%)
Short Float %6.02%
Short Ratio8.75
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)0
Avg EPS beat(2)-85.59%
Min EPS beat(2)-163.84%
Max EPS beat(2)-7.35%
EPS beat(4)N/A
Avg EPS beat(4)N/A
Min EPS beat(4)N/A
Max EPS beat(4)N/A
EPS beat(8)N/A
Avg EPS beat(8)N/A
EPS beat(12)N/A
Avg EPS beat(12)N/A
EPS beat(16)N/A
Avg EPS beat(16)N/A
Revenue beat(2)1
Avg Revenue beat(2)7.87%
Min Revenue beat(2)-98.97%
Max Revenue beat(2)114.71%
Revenue beat(4)N/A
Avg Revenue beat(4)N/A
Min Revenue beat(4)N/A
Max Revenue beat(4)N/A
Revenue beat(8)N/A
Avg Revenue beat(8)N/A
Revenue beat(12)N/A
Avg Revenue beat(12)N/A
Revenue beat(16)N/A
Avg Revenue beat(16)N/A
PT rev (1m)0%
PT rev (3m)0%
EPS NQ rev (1m)0%
EPS NQ rev (3m)37.37%
EPS NY rev (1m)0%
EPS NY rev (3m)-95.87%
Revenue NQ rev (1m)0%
Revenue NQ rev (3m)64.12%
Revenue NY rev (1m)0%
Revenue NY rev (3m)6.99%
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S 1104.31
P/FCF N/A
P/OCF N/A
P/B 1.91
P/tB 1.91
EV/EBITDA N/A
EPS(TTM)-10.08
EYN/A
EPS(NY)-2.12
Fwd EYN/A
FCF(TTM)-1.86
FCFYN/A
OCF(TTM)-1.83
OCFYN/A
SpS0.02
BVpS9.42
TBVpS9.42
PEG (NY)N/A
PEG (5Y)N/A
Graham NumberN/A
Profitability
Industry RankSector Rank
ROA -19.17%
ROE -20.83%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM N/A
FCFM N/A
ROA(3y)-30.64%
ROA(5y)N/A
ROE(3y)-35.78%
ROE(5y)N/A
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score4
Asset Turnover0
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 104.89%
Cap/Sales 224.52%
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 27.77
Quick Ratio 27.77
Altman-Z 13.37
F-Score4
WACC8.84%
ROIC/WACCN/A
Cap/Depr(3y)237.63%
Cap/Depr(5y)N/A
Cap/Sales(3y)N/A
Cap/Sales(5y)N/A
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)-53868.89%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%22.82%
EPS Next Y100.45%
EPS Next 2Y31.63%
EPS Next 3Y17.26%
EPS Next 5Y8.52%
Revenue 1Y (TTM)611.92%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%-82.68%
Revenue Next Year10618.3%
Revenue Next 2Y666.69%
Revenue Next 3Y264.4%
Revenue Next 5Y121.87%
EBIT growth 1Y-77.44%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year29.99%
EBIT Next 3Y-35.61%
EBIT Next 5YN/A
FCF growth 1Y-67.24%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y-74.24%
OCF growth 3YN/A
OCF growth 5YN/A

SEPTERNA INC / SEPN FAQ

What is the fundamental rating for SEPN stock?

ChartMill assigns a fundamental rating of 3 / 10 to SEPN.


What is the valuation status of SEPTERNA INC (SEPN) stock?

ChartMill assigns a valuation rating of 0 / 10 to SEPTERNA INC (SEPN). This can be considered as Overvalued.


What is the profitability of SEPN stock?

SEPTERNA INC (SEPN) has a profitability rating of 1 / 10.