Logo image of SEPN

SEPTERNA INC (SEPN) Stock Price, Forecast & Analysis

USA - Nasdaq - NASDAQ:SEPN - US81734D1046 - Common Stock

26.17 USD
-1.45 (-5.25%)
Last: 12/2/2025, 8:06:18 PM
26.1689 USD
0 (0%)
After Hours: 12/2/2025, 8:06:18 PM

SEPN Key Statistics, Chart & Performance

Key Statistics
Market Cap1.17B
Revenue(TTM)22.05M
Net Income(TTM)-58.81M
Shares44.77M
Float42.82M
52 Week High29.74
52 Week Low4.17
Yearly DividendN/A
Dividend YieldN/A
EPS(TTM)-1.78
PEN/A
Fwd PEN/A
Earnings (Next)03-25 2026-03-25
IPO2024-10-25
Sector
GICS SectorHealth Care
GICS IndustryPharmaceuticals
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryPharmaceuticals


SEPN short term performance overview.The bars show the price performance of SEPN in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 0 50 100 150

SEPN long term performance overview.The bars show the price performance of SEPN in the last 1, 2 and 3 years. 1 year 2 years 3 years 0.5 1 1.5

The current stock price of SEPN is 26.17 USD. In the past month the price increased by 30.52%. In the past year, price increased by 1.63%.

SEPTERNA INC / SEPN Daily stock chart

SEPN Latest News, Press Relases and Analysis

SEPN Competitors/Peers

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About SEPN

Company Profile

SEPN logo image Septerna, Inc. is a clinical-stage biotechnology company, which engages in pioneering a new era of G protein-coupled receptor oral small molecule drug discovery powered by proprietary Native Complex PlatformTM. The company is headquartered in South San Francisco, California and currently employs 75 full-time employees. The company went IPO on 2024-10-25. The firm is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. The company is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. The company is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.

Company Info

SEPTERNA INC

250 East Grand Avenue, Suite 65

South San Francisco CALIFORNIA US

Employees: 75

SEPN Company Website

Phone: 16503383533

SEPTERNA INC / SEPN FAQ

What does SEPN do?

Septerna, Inc. is a clinical-stage biotechnology company, which engages in pioneering a new era of G protein-coupled receptor oral small molecule drug discovery powered by proprietary Native Complex PlatformTM. The company is headquartered in South San Francisco, California and currently employs 75 full-time employees. The company went IPO on 2024-10-25. The firm is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. The company is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. The company is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.


What is the stock price of SEPTERNA INC today?

The current stock price of SEPN is 26.17 USD. The price decreased by -5.25% in the last trading session.


Does SEPN stock pay dividends?

SEPN does not pay a dividend.


How is the ChartMill rating for SEPTERNA INC?

SEPN has a ChartMill Technical rating of 10 out of 10 and a ChartMill Fundamental rating of 4 out of 10.


Which stock exchange lists SEPN stock?

SEPN stock is listed on the Nasdaq exchange.


How is the valuation of SEPTERNA INC (SEPN) based on its PE ratio?

SEPTERNA INC (SEPN) does not have a PE ratio as the earnings reported over the last twelve months were negative (-1.78).


What is SEPTERNA INC worth?

SEPTERNA INC (SEPN) has a market capitalization of 1.17B USD. This makes SEPN a Small Cap stock.


SEPN Technical Analysis

ChartMill assigns a technical rating of 10 / 10 to SEPN. When comparing the yearly performance of all stocks, SEPN is one of the better performing stocks in the market, outperforming 92.6% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

SEPN Fundamental Analysis

ChartMill assigns a fundamental rating of 4 / 10 to SEPN. No worries on liquidiy or solvency for SEPN as it has an excellent financial health rating, but there are worries on the profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

SEPN Financial Highlights

Over the last trailing twelve months SEPN reported a non-GAAP Earnings per Share(EPS) of -1.78. The EPS decreased by -53868.89% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -12.88%
ROE -14%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%102.13%
Sales Q2Q%12113.07%
EPS 1Y (TTM)-53868.89%
Revenue 1Y (TTM)611.92%

SEPN Forecast & Estimates

11 analysts have analysed SEPN and the average price target is 28.22 USD. This implies a price increase of 7.83% is expected in the next year compared to the current price of 26.17.

For the next year, analysts expect an EPS growth of 100.45% and a revenue growth 10618.3% for SEPN


Analysts
Analysts80
Price Target28.22 (7.83%)
EPS Next Y100.45%
Revenue Next Year10618.3%

SEPN Ownership

Ownership
Inst Owners99.28%
Ins Owners2.94%
Short Float %4.49%
Short Ratio5.53