SEPTERNA INC (SEPN) Stock Price & Overview

NASDAQ:SEPN • US81734D1046

25.14 USD
-1.3 (-4.93%)
At close: Mar 13, 2026
25.14 USD
0 (0%)
After Hours: 3/13/2026, 8:00:02 PM

The current stock price of SEPN is 25.14 USD. Today SEPN is down by -4.93%. In the past month the price decreased by -2.41%. In the past year, price increased by 299.05%.

SEPN Key Statistics

52-Week Range4.66 - 32.63
Current SEPN stock price positioned within its 52-week range.
1-Month Range24.96 - 32.63
Current SEPN stock price positioned within its 1-month range.
Market Cap
1.126B
P/E
N/A
Fwd P/E
N/A
EPS (TTM)
-1.38
Dividend Yield
N/A

SEPN Stock Performance

Today
-4.93%
1 Week
-12.65%
1 Month
-2.41%
3 Months
-1.18%
Longer-term
6 Months +76.05%
1 Year +299.05%
2 Years N/A
3 Years N/A
5 Years N/A
10 Years N/A

SEPN Stock Chart

SEPTERNA INC / SEPN Daily stock chart

SEPN Technical Analysis

ChartMill assigns a technical rating of 5 / 10 to SEPN. When comparing the yearly performance of all stocks, SEPN is one of the better performing stocks in the market, outperforming 98.3% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating
SEPN Full Technical Analysis Report

SEPN Fundamental Analysis

ChartMill assigns a fundamental rating of 3 / 10 to SEPN. No worries on liquidiy or solvency for SEPN as it has an excellent financial health rating, but there are worries on the profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend
SEPN Full Fundamental Analysis Report

SEPN Earnings

On March 9, 2026 SEPN reported an EPS of -0.24 and a revenue of 24.12M. The company beat EPS expectations (7.27% surprise) and beat revenue expectations (36.41% surprise).

Next Earnings DateMay 13, 2026
Last Earnings DateMar 9, 2026
PeriodQ4 / 2025
EPS Reported-$0.24
Revenue Reported24.118M
EPS Surprise 7.27%
Revenue Surprise 36.41%
SEPN Earnings History

SEPN Forecast & Estimates

14 analysts have analysed SEPN and the average price target is 34.53 USD. This implies a price increase of 37.37% is expected in the next year compared to the current price of 25.14.

For the next year, analysts expect an EPS growth of 8.26% and a revenue growth 93.34% for SEPN


Analysts
Analysts82.86
Price Target34.53 (37.35%)
EPS Next Y8.26%
Revenue Next Year93.34%
SEPN Forecast & Estimates

SEPN Groups

Sector & Classification

SEPN Financial Highlights

Over the last trailing twelve months SEPN reported a non-GAAP Earnings per Share(EPS) of -1.38.


Income Statements
Revenue(TTM)N/A
Net Income(TTM)-58.81M
Industry RankSector Rank
PM (TTM) N/A
ROA -9.69%
ROE -15.13%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%62.5%
Sales Q2Q%11276.42%
EPS 1Y (TTM)N/A
Revenue 1Y (TTM)N/A
SEPN financials

SEPN Ownership

Ownership
Inst Owners102.27%
Shares44.77M
Float42.93M
Ins Owners3.15%
Short Float %4.15%
Short Ratio5.89
SEPN Ownership

SEPN Competitors/Peers

The largest stocks on the US markets in the "Pharmaceuticals" sub-industry
Full List
SymbolCompany NameTechnical RatingFundamental RatingFPEMarket Cap
LLY ELI LILLY & CO28.18921.899B
JNJ JOHNSON & JOHNSON20.74583.292B
MRK MERCK & CO. INC.22.34286.575B
PFE PFIZER INC8.9152.733B
BMY BRISTOL-MYERS SQUIBB CO9.33120.05B
ZTS ZOETIS INC16.3448.739B
RPRX ROYALTY PHARMA PLC- CL A8.8326.461B
VTRS VIATRIS INC5.3915.889B
ELAN ELANCO ANIMAL HEALTH INC21.8111.276B
AXSM AXSOME THERAPEUTICS INC N/A7.883B
BLTE BELITE BIO INC - ADR N/A6.361B
TERN TERNS PHARMACEUTICALS INC N/A4.698B
LGND LIGAND PHARMACEUTICALS23.94.217B

About SEPN

Company Profile

SEPN logo image Septerna, Inc. is a clinical-stage biotechnology company, which engages in pioneering a new era of G protein-coupled receptor oral small molecule drug discovery powered by proprietary Native Complex PlatformTM. The company is headquartered in South San Francisco, California and currently employs 75 full-time employees. The company went IPO on 2024-10-25. The firm is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. The company is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. The company is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.

Company Info

IPO: 2024-10-25

SEPTERNA INC

250 East Grand Avenue, Suite 65

South San Francisco CALIFORNIA US

Employees: 75

SEPN Company Website

Phone: 16503383533

SEPTERNA INC / SEPN FAQ

What does SEPN do?

Septerna, Inc. is a clinical-stage biotechnology company, which engages in pioneering a new era of G protein-coupled receptor oral small molecule drug discovery powered by proprietary Native Complex PlatformTM. The company is headquartered in South San Francisco, California and currently employs 75 full-time employees. The company went IPO on 2024-10-25. The firm is developing G protein-coupled receptor (GPCR) oral small-molecule drug discovery powered by its proprietary Native Complex Platform. Its pipeline of product candidates is focused on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. Its industrial-scale Native Complex Platform is designed to target certain GPCRs for the first time, uncover novel binding pockets for validated receptors, and pursue a wide spectrum of pharmacologies, including agonists, antagonists, and allosteric modulators, to achieve desired therapeutic effects. The company is advancing a deep portfolio of oral small molecule GPCR-targeted programs with novel mechanistic approaches to treat diseases across multiple therapeutic areas for patients with unmet needs. The company is focused on therapeutic areas, such as neurology, women’s health, cardiovascular, and respiratory disease.


Can you provide the latest stock price for SEPTERNA INC?

The current stock price of SEPN is 25.14 USD. The price decreased by -4.93% in the last trading session.


What is the dividend status of SEPTERNA INC?

SEPN does not pay a dividend.


What is the ChartMill rating of SEPTERNA INC stock?

SEPN has a ChartMill Technical rating of 5 out of 10 and a ChartMill Fundamental rating of 3 out of 10.


What do analysts say about SEPTERNA INC (SEPN) stock?

14 analysts have analysed SEPN and the average price target is 34.53 USD. This implies a price increase of 37.37% is expected in the next year compared to the current price of 25.14.


What is the employee count for SEPN stock?

SEPTERNA INC (SEPN) currently has 75 employees.


What is the outstanding short interest for SEPTERNA INC?

The outstanding short interest for SEPTERNA INC (SEPN) is 4.15% of its float.