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PRIME MEDICINE INC (PRME) Stock Fundamental Analysis

USA - NASDAQ:PRME - US74168J1016 - Common Stock

4.18 USD
-0.22 (-5%)
Last: 11/6/2025, 4:14:05 PM
4.18 USD
0 (0%)
After Hours: 11/6/2025, 4:14:05 PM
Fundamental Rating

3

PRME gets a fundamental rating of 3 out of 10. The analysis compared the fundamentals against 534 industry peers in the Biotechnology industry. PRME scores quite bad on profitability, while its financial health is fine. Not spectacular, but in line with the averages. PRME is valied quite expensively at the moment, while it does show a decent growth rate.


Dividend Valuation Growth Profitability Health

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0

1. Profitability

1.1 Basic Checks

PRME had negative earnings in the past year.
In the past year PRME has reported a negative cash flow from operations.
In the past 5 years PRME always reported negative net income.
In the past 5 years PRME always reported negative operating cash flow.
PRME Yearly Net Income VS EBIT VS OCF VS FCFPRME Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2019 2020 2021 2022 2023 2024 -50M -100M -150M -200M

1.2 Ratios

PRME has a worse Return On Assets (-71.42%) than 62.36% of its industry peers.
PRME has a worse Return On Equity (-327.43%) than 72.47% of its industry peers.
Industry RankSector Rank
ROA -71.42%
ROE -327.43%
ROIC N/A
ROA(3y)-69.15%
ROA(5y)-55.54%
ROE(3y)-107.23%
ROE(5y)-82.73%
ROIC(3y)N/A
ROIC(5y)N/A
PRME Yearly ROA, ROE, ROICPRME Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2019 2020 2021 2022 2023 2024 -50 -100 -150

1.3 Margins

PRME does not have Profit Margin and Operating Margin and Gross Margin available, so we won't be analyzing them here.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM N/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
PRME Yearly Profit, Operating, Gross MarginsPRME Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2019 2020 2021 2022 2023 2024 -2K -4K -6K

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6

2. Health

2.1 Basic Checks

PRME does not have a ROIC to compare to the WACC, probably because it is not profitable.
Compared to 1 year ago, PRME has more shares outstanding
Compared to 5 years ago, PRME has more shares outstanding
PRME has no outstanding debt. Therefor its Debt/Equity and Debt/FCF ratios are 0 and belong to the best of the industry.
PRME Yearly Shares OutstandingPRME Yearly Shares OutstandingYearly Shares Outstanding 2019 2020 2021 2022 2023 2024 20M 40M 60M 80M 100M
PRME Yearly Total Debt VS Total AssetsPRME Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2019 2020 2021 2022 2023 2024 100M 200M 300M

2.2 Solvency

Based on the Altman-Z score of -3.88, we must say that PRME is in the distress zone and has some risk of bankruptcy.
PRME's Altman-Z score of -3.88 is in line compared to the rest of the industry. PRME outperforms 43.07% of its industry peers.
There is no outstanding debt for PRME. This means it has a Debt/Equity and Debt/FCF ratio of 0 and it is amongst the best of the sector and industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z -3.88
ROIC/WACCN/A
WACC8.74%
PRME Yearly LT Debt VS Equity VS FCFPRME Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2019 2020 2021 2022 2023 2024 0 100M -100M 200M 300M

2.3 Liquidity

PRME has a Current Ratio of 3.56. This indicates that PRME is financially healthy and has no problem in meeting its short term obligations.
Looking at the Current ratio, with a value of 3.56, PRME is in line with its industry, outperforming 41.57% of the companies in the same industry.
PRME has a Quick Ratio of 3.56. This indicates that PRME is financially healthy and has no problem in meeting its short term obligations.
PRME has a Quick ratio of 3.56. This is comparable to the rest of the industry: PRME outperforms 43.63% of its industry peers.
Industry RankSector Rank
Current Ratio 3.56
Quick Ratio 3.56
PRME Yearly Current Assets VS Current LiabilitesPRME Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2019 2020 2021 2022 2023 2024 50M 100M 150M 200M 250M

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4

3. Growth

3.1 Past

PRME shows a strong growth in Earnings Per Share. In the last year, the EPS has been growing by 28.11%, which is quite impressive.
PRME shows a strong growth in Revenue. In the last year, the Revenue has grown by 739.42%.
EPS 1Y (TTM)28.11%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%10.87%
Revenue 1Y (TTM)739.42%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%N/A

3.2 Future

Based on estimates for the next years, PRME will show a quite strong growth in Earnings Per Share. The EPS will grow by 9.03% on average per year.
PRME is expected to show a strong growth in Revenue. In the coming years, the Revenue will grow by 44.53% yearly.
EPS Next Y26.14%
EPS Next 2Y19.56%
EPS Next 3Y13.3%
EPS Next 5Y9.03%
Revenue Next Year780.04%
Revenue Next 2Y77.83%
Revenue Next 3Y176.76%
Revenue Next 5Y44.53%

3.3 Evolution

PRME Yearly Revenue VS EstimatesPRME Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2020 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 100M 200M 300M 400M 500M
PRME Yearly EPS VS EstimatesPRME Yearly EPS VS EstimatesYearly EPS VS Estimates 2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 0 -1 -2

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0

4. Valuation

4.1 Price/Earnings Ratio

PRME reported negative earnings for the last year, which makes the Price/Earnings Ratio negative.
Also next year PRME is expected to report negative earnings again, which makes the also the Forward Price/Earnings Ratio negative.
Industry RankSector Rank
PE N/A
Fwd PE N/A
PRME Price Earnings VS Forward Price EarningsPRME Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 20 40 60 80

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
PRME Per share dataPRME EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 -0.5 -1 -1.5

4.3 Compensation for Growth

A more expensive valuation may be justified as PRME's earnings are expected to grow with 13.30% in the coming years.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y19.56%
EPS Next 3Y13.3%

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0

5. Dividend

5.1 Amount

No dividends for PRME!.
Industry RankSector Rank
Dividend Yield N/A

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PRIME MEDICINE INC

NASDAQ:PRME (11/6/2025, 4:14:05 PM)

After market: 4.18 0 (0%)

4.18

-0.22 (-5%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)10-31 2025-10-31
Earnings (Next)02-26 2026-02-26/bmo
Inst Owners44.27%
Inst Owner Change3.79%
Ins Owners11.72%
Ins Owner Change1.37%
Market Cap730.91M
Revenue(TTM)4.96M
Net Income(TTM)-199275000
Analysts80
Price Target6.97 (66.75%)
Short Float %11.04%
Short Ratio4.37
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)0
Avg EPS beat(2)-16.53%
Min EPS beat(2)-22.51%
Max EPS beat(2)-10.55%
EPS beat(4)1
Avg EPS beat(4)-4.94%
Min EPS beat(4)-22.51%
Max EPS beat(4)22.47%
EPS beat(8)2
Avg EPS beat(8)-9.8%
EPS beat(12)N/A
Avg EPS beat(12)N/A
EPS beat(16)N/A
Avg EPS beat(16)N/A
Revenue beat(2)1
Avg Revenue beat(2)4.38%
Min Revenue beat(2)-27.12%
Max Revenue beat(2)35.89%
Revenue beat(4)2
Avg Revenue beat(4)138.95%
Min Revenue beat(4)-97.38%
Max Revenue beat(4)644.42%
Revenue beat(8)N/A
Avg Revenue beat(8)N/A
Revenue beat(12)N/A
Avg Revenue beat(12)N/A
Revenue beat(16)N/A
Avg Revenue beat(16)N/A
PT rev (1m)-6.21%
PT rev (3m)-7.12%
EPS NQ rev (1m)0%
EPS NQ rev (3m)14.18%
EPS NY rev (1m)0%
EPS NY rev (3m)7.83%
Revenue NQ rev (1m)0%
Revenue NQ rev (3m)-4.64%
Revenue NY rev (1m)0%
Revenue NY rev (3m)36.97%
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S 147.33
P/FCF N/A
P/OCF N/A
P/B 12.01
P/tB 12.01
EV/EBITDA N/A
EPS(TTM)-1.56
EYN/A
EPS(NY)-0.94
Fwd EYN/A
FCF(TTM)-0.61
FCFYN/A
OCF(TTM)-0.57
OCFYN/A
SpS0.03
BVpS0.35
TBVpS0.35
PEG (NY)N/A
PEG (5Y)N/A
Graham NumberN/A
Profitability
Industry RankSector Rank
ROA -71.42%
ROE -327.43%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM N/A
FCFM N/A
ROA(3y)-69.15%
ROA(5y)-55.54%
ROE(3y)-107.23%
ROE(5y)-82.73%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score5
Asset Turnover0.02
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 103.26%
Cap/Sales 142.35%
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 3.56
Quick Ratio 3.56
Altman-Z -3.88
F-Score5
WACC8.74%
ROIC/WACCN/A
Cap/Depr(3y)343.92%
Cap/Depr(5y)671.96%
Cap/Sales(3y)N/A
Cap/Sales(5y)N/A
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)28.11%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%10.87%
EPS Next Y26.14%
EPS Next 2Y19.56%
EPS Next 3Y13.3%
EPS Next 5Y9.03%
Revenue 1Y (TTM)739.42%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%N/A
Revenue Next Year780.04%
Revenue Next 2Y77.83%
Revenue Next 3Y176.76%
Revenue Next 5Y44.53%
EBIT growth 1Y8.63%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year17.21%
EBIT Next 3Y7.66%
EBIT Next 5YN/A
FCF growth 1Y31.75%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y30.21%
OCF growth 3YN/A
OCF growth 5YN/A

PRIME MEDICINE INC / PRME FAQ

What is the ChartMill fundamental rating of PRIME MEDICINE INC (PRME) stock?

ChartMill assigns a fundamental rating of 3 / 10 to PRME.


What is the valuation status for PRME stock?

ChartMill assigns a valuation rating of 0 / 10 to PRIME MEDICINE INC (PRME). This can be considered as Overvalued.


What is the profitability of PRME stock?

PRIME MEDICINE INC (PRME) has a profitability rating of 0 / 10.


What is the expected EPS growth for PRIME MEDICINE INC (PRME) stock?

The Earnings per Share (EPS) of PRIME MEDICINE INC (PRME) is expected to grow by 26.14% in the next year.