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PUMA BIOTECHNOLOGY INC (PBYI) Stock Fundamental Analysis

USA - NASDAQ:PBYI - US74587V1070 - Common Stock

5.99 USD
+1.09 (+22.24%)
Last: 11/7/2025, 8:07:10 PM
6.01 USD
+0.02 (+0.33%)
After Hours: 11/7/2025, 8:07:10 PM
Fundamental Rating

5

PBYI gets a fundamental rating of 5 out of 10. The analysis compared the fundamentals against 531 industry peers in the Biotechnology industry. PBYI scores excellent on profitability, but there are some minor concerns on its financial health. PBYI is cheap, but on the other hand it scores bad on growth. This makes PBYI very considerable for value investing!


Dividend Valuation Growth Profitability Health

8

1. Profitability

1.1 Basic Checks

PBYI had positive earnings in the past year.
In the past year PBYI had a positive cash flow from operations.
The reported net income has been mixed in the past 5 years: PBYI reported negative net income in multiple years.
Of the past 5 years PBYI 4 years had a positive operating cash flow.
PBYI Yearly Net Income VS EBIT VS OCF VS FCFPBYI Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -100M -200M

1.2 Ratios

PBYI's Return On Assets of 24.86% is amongst the best of the industry. PBYI outperforms 97.76% of its industry peers.
PBYI has a better Return On Equity (46.27%) than 98.51% of its industry peers.
PBYI's Return On Invested Capital of 31.42% is amongst the best of the industry. PBYI outperforms 99.25% of its industry peers.
Measured over the past 3 years, the Average Return On Invested Capital for PBYI is above the industry average of 15.48%.
The 3 year average ROIC (17.97%) for PBYI is below the current ROIC(31.42%), indicating increased profibility in the last year.
Industry RankSector Rank
ROA 24.86%
ROE 46.27%
ROIC 31.42%
ROA(3y)7.85%
ROA(5y)-2.77%
ROE(3y)24.42%
ROE(5y)N/A
ROIC(3y)17.97%
ROIC(5y)N/A
PBYI Yearly ROA, ROE, ROICPBYI Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 500 -500 1K

1.3 Margins

PBYI has a Profit Margin of 20.35%. This is amongst the best in the industry. PBYI outperforms 94.59% of its industry peers.
PBYI's Operating Margin of 19.35% is amongst the best of the industry. PBYI outperforms 94.22% of its industry peers.
PBYI's Operating Margin has improved in the last couple of years.
The Gross Margin of PBYI (72.33%) is better than 82.84% of its industry peers.
In the last couple of years the Gross Margin of PBYI has declined.
Industry RankSector Rank
OM 19.35%
PM (TTM) 20.35%
GM 72.33%
OM growth 3Y196.89%
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3Y-1.26%
GM growth 5Y-3.58%
PBYI Yearly Profit, Operating, Gross MarginsPBYI Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -200 -400 -600 -800 -1K

5

2. Health

2.1 Basic Checks

PBYI has a Return on Invested Capital (ROIC), which is well above the Cost of Capital (WACC), which means it is creating value.
PBYI has more shares outstanding than it did 1 year ago.
The number of shares outstanding for PBYI has been increased compared to 5 years ago.
Compared to 1 year ago, PBYI has an improved debt to assets ratio.
PBYI Yearly Shares OutstandingPBYI Yearly Shares OutstandingYearly Shares Outstanding 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 10M 20M 30M 40M
PBYI Yearly Total Debt VS Total AssetsPBYI Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 50M 100M 150M 200M 250M

2.2 Solvency

PBYI has an Altman-Z score of -5.02. This is a bad value and indicates that PBYI is not financially healthy and even has some risk of bankruptcy.
Looking at the Altman-Z score, with a value of -5.02, PBYI is doing worse than 60.45% of the companies in the same industry.
The Debt to FCF ratio of PBYI is 1.01, which is an excellent value as it means it would take PBYI, only 1.01 years of fcf income to pay off all of its debts.
Looking at the Debt to FCF ratio, with a value of 1.01, PBYI belongs to the top of the industry, outperforming 94.22% of the companies in the same industry.
PBYI has a Debt/Equity ratio of 0.10. This is a healthy value indicating a solid balance between debt and equity.
PBYI's Debt to Equity ratio of 0.10 is on the low side compared to the rest of the industry. PBYI is outperformed by 64.18% of its industry peers.
Although PBYI does not score too well on debt/equity it has very limited outstanding debt, which is well covered by the FCF. We will not put too much weight on the debt/equity number as it may be because of low equity, which could be a consequence of a share buyback program for instance. This needs to be investigated.
Industry RankSector Rank
Debt/Equity 0.1
Debt/FCF 1.01
Altman-Z -5.02
ROIC/WACC3.29
WACC9.56%
PBYI Yearly LT Debt VS Equity VS FCFPBYI Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 100M -100M 200M -200M

2.3 Liquidity

PBYI has a Current Ratio of 1.73. This is a normal value and indicates that PBYI is financially healthy and should not expect problems in meeting its short term obligations.
With a Current ratio value of 1.73, PBYI is not doing good in the industry: 79.10% of the companies in the same industry are doing better.
A Quick Ratio of 1.62 indicates that PBYI should not have too much problems paying its short term obligations.
The Quick ratio of PBYI (1.62) is worse than 79.66% of its industry peers.
Industry RankSector Rank
Current Ratio 1.73
Quick Ratio 1.62
PBYI Yearly Current Assets VS Current LiabilitesPBYI Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 50M 100M 150M 200M

2

3. Growth

3.1 Past

PBYI shows a strong growth in Earnings Per Share. In the last year, the EPS has been growing by 54.17%, which is quite impressive.
PBYI shows a decrease in Revenue. In the last year, the revenue decreased by -2.19%.
Measured over the past years, PBYI shows a decrease in Revenue. The Revenue has been decreasing by -3.28% on average per year.
EPS 1Y (TTM)54.17%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-58.54%
Revenue 1Y (TTM)-2.19%
Revenue growth 3Y-3.09%
Revenue growth 5Y-3.28%
Sales Q2Q%-32.3%

3.2 Future

PBYI is expected to show a very negative growth in Earnings Per Share. In the coming years, the EPS will decrease by -12.89% yearly.
PBYI is expected to show a decrease in Revenue. In the coming years, the Revenue will decrease by -1.09% yearly.
EPS Next Y-17.31%
EPS Next 2Y-26.51%
EPS Next 3Y-17.16%
EPS Next 5Y-12.89%
Revenue Next Year-3.32%
Revenue Next 2Y-3.85%
Revenue Next 3Y-2.82%
Revenue Next 5Y-1.09%

3.3 Evolution

The Revenue growth rate is accelerating: in the next years the growth will be better than in the last years.
PBYI Yearly Revenue VS EstimatesPBYI Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 50M 100M 150M 200M 250M
PBYI Yearly EPS VS EstimatesPBYI Yearly EPS VS EstimatesYearly EPS VS Estimates 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 0 -2 -4 -6 -8

7

4. Valuation

4.1 Price/Earnings Ratio

PBYI is valuated reasonably with a Price/Earnings ratio of 8.09.
Based on the Price/Earnings ratio, PBYI is valued cheaper than 98.13% of the companies in the same industry.
Compared to an average S&P500 Price/Earnings ratio of 26.06, PBYI is valued rather cheaply.
A Price/Forward Earnings ratio of 18.18 indicates a rather expensive valuation of PBYI.
Based on the Price/Forward Earnings ratio, PBYI is valued cheaper than 93.84% of the companies in the same industry.
Compared to an average S&P500 Price/Forward Earnings ratio of 32.73, PBYI is valued a bit cheaper.
Industry RankSector Rank
PE 8.09
Fwd PE 18.18
PBYI Price Earnings VS Forward Price EarningsPBYI Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 20 40 60 80

4.2 Price Multiples

PBYI's Enterprise Value to EBITDA ratio is rather cheap when compared to the industry. PBYI is cheaper than 98.88% of the companies in the same industry.
Compared to the rest of the industry, the Price/Free Cash Flow ratio of PBYI indicates a rather cheap valuation: PBYI is cheaper than 99.44% of the companies listed in the same industry.
Industry RankSector Rank
P/FCF 6.82
EV/EBITDA 3.65
PBYI Per share dataPBYI EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 1 2 3 4

4.3 Compensation for Growth

PBYI has an outstanding profitability rating, which may justify a higher PE ratio.
A cheap valuation may be justified as PBYI's earnings are expected to decrease with -17.16% in the coming years.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y-26.51%
EPS Next 3Y-17.16%

0

5. Dividend

5.1 Amount

No dividends for PBYI!.
Industry RankSector Rank
Dividend Yield N/A

PUMA BIOTECHNOLOGY INC

NASDAQ:PBYI (11/7/2025, 8:07:10 PM)

After market: 6.01 +0.02 (+0.33%)

5.99

+1.09 (+22.24%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)11-06 2025-11-06/amc
Earnings (Next)02-25 2026-02-25/amc
Inst Owners68.37%
Inst Owner Change-2.98%
Ins Owners15.13%
Ins Owner Change0.07%
Market Cap301.72M
Revenue(TTM)230.47M
Net Income(TTM)48.45M
Analysts42.86
Price Target4.42 (-26.21%)
Short Float %7.87%
Short Ratio5.99
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)2
Avg EPS beat(2)204.35%
Min EPS beat(2)14.59%
Max EPS beat(2)394.12%
EPS beat(4)4
Avg EPS beat(4)173.94%
Min EPS beat(4)14.59%
Max EPS beat(4)394.12%
EPS beat(8)7
Avg EPS beat(8)102.62%
EPS beat(12)10
Avg EPS beat(12)105.29%
EPS beat(16)13
Avg EPS beat(16)203.97%
Revenue beat(2)2
Avg Revenue beat(2)1.23%
Min Revenue beat(2)1.23%
Max Revenue beat(2)1.23%
Revenue beat(4)4
Avg Revenue beat(4)6.13%
Min Revenue beat(4)1.23%
Max Revenue beat(4)11.71%
Revenue beat(8)6
Avg Revenue beat(8)2.95%
Revenue beat(12)10
Avg Revenue beat(12)4.59%
Revenue beat(16)12
Avg Revenue beat(16)4.1%
PT rev (1m)0%
PT rev (3m)0%
EPS NQ rev (1m)0%
EPS NQ rev (3m)-59.09%
EPS NY rev (1m)0%
EPS NY rev (3m)4.47%
Revenue NQ rev (1m)0%
Revenue NQ rev (3m)-15%
Revenue NY rev (1m)0%
Revenue NY rev (3m)-0.6%
Valuation
Industry RankSector Rank
PE 8.09
Fwd PE 18.18
P/S 1.27
P/FCF 6.82
P/OCF 6.8
P/B 2.88
P/tB 5.16
EV/EBITDA 3.65
EPS(TTM)0.74
EY12.35%
EPS(NY)0.33
Fwd EY5.5%
FCF(TTM)0.88
FCFY14.66%
OCF(TTM)0.88
OCFY14.7%
SpS4.73
BVpS2.08
TBVpS1.16
PEG (NY)N/A
PEG (5Y)N/A
Graham Number5.88
Profitability
Industry RankSector Rank
ROA 24.86%
ROE 46.27%
ROCE 39.77%
ROIC 31.42%
ROICexc 183.86%
ROICexgc N/A
OM 19.35%
PM (TTM) 20.35%
GM 72.33%
FCFM 18.58%
ROA(3y)7.85%
ROA(5y)-2.77%
ROE(3y)24.42%
ROE(5y)N/A
ROIC(3y)17.97%
ROIC(5y)N/A
ROICexc(3y)84.91%
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)22.75%
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3Y271.17%
ROICexc growth 5YN/A
OM growth 3Y196.89%
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3Y-1.26%
GM growth 5Y-3.58%
F-Score6
Asset Turnover1.22
Health
Industry RankSector Rank
Debt/Equity 0.1
Debt/FCF 1.01
Debt/EBITDA 0.19
Cap/Depr 1.04%
Cap/Sales 0.05%
Interest Coverage 5.43
Cash Conversion 77.32%
Profit Quality 91.27%
Current Ratio 1.73
Quick Ratio 1.62
Altman-Z -5.02
F-Score6
WACC9.56%
ROIC/WACC3.29
Cap/Depr(3y)62.9%
Cap/Depr(5y)77.72%
Cap/Sales(3y)2.82%
Cap/Sales(5y)3.47%
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)54.17%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-58.54%
EPS Next Y-17.31%
EPS Next 2Y-26.51%
EPS Next 3Y-17.16%
EPS Next 5Y-12.89%
Revenue 1Y (TTM)-2.19%
Revenue growth 3Y-3.09%
Revenue growth 5Y-3.28%
Sales Q2Q%-32.3%
Revenue Next Year-3.32%
Revenue Next 2Y-3.85%
Revenue Next 3Y-2.82%
Revenue Next 5Y-1.09%
EBIT growth 1Y135.74%
EBIT growth 3Y187.73%
EBIT growth 5YN/A
EBIT Next Year58.8%
EBIT Next 3Y9.99%
EBIT Next 5YN/A
FCF growth 1Y291%
FCF growth 3Y23.46%
FCF growth 5Y11.98%
OCF growth 1Y43.58%
OCF growth 3Y23.52%
OCF growth 5Y11.7%

PUMA BIOTECHNOLOGY INC / PBYI FAQ

Can you provide the ChartMill fundamental rating for PUMA BIOTECHNOLOGY INC?

ChartMill assigns a fundamental rating of 5 / 10 to PBYI.


Can you provide the valuation status for PUMA BIOTECHNOLOGY INC?

ChartMill assigns a valuation rating of 7 / 10 to PUMA BIOTECHNOLOGY INC (PBYI). This can be considered as Undervalued.


What is the profitability of PBYI stock?

PUMA BIOTECHNOLOGY INC (PBYI) has a profitability rating of 8 / 10.


What are the PE and PB ratios of PUMA BIOTECHNOLOGY INC (PBYI) stock?

The Price/Earnings (PE) ratio for PUMA BIOTECHNOLOGY INC (PBYI) is 8.09 and the Price/Book (PB) ratio is 2.88.


What is the financial health of PUMA BIOTECHNOLOGY INC (PBYI) stock?

The financial health rating of PUMA BIOTECHNOLOGY INC (PBYI) is 5 / 10.