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MADRIGAL PHARMACEUTICALS INC (MDGL) Stock Fundamental Analysis

USA - Nasdaq - NASDAQ:MDGL - US5588681057 - Common Stock

571.44 USD
+0.11 (+0.02%)
Last: 12/12/2025, 8:00:00 PM
580.5 USD
+9.06 (+1.59%)
After Hours: 12/12/2025, 8:00:00 PM
Fundamental Rating

3

Overall MDGL gets a fundamental rating of 3 out of 10. We evaluated MDGL against 531 industry peers in the Biotechnology industry. MDGL scores quite bad on profitability, while its financial health is fine. Not spectacular, but in line with the averages. MDGL is quite expensive at the moment. It does show a decent growth rate.


Dividend Valuation Growth Profitability Health

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2

1. Profitability

1.1 Basic Checks

In the past year MDGL has reported negative net income.
MDGL had a negative operating cash flow in the past year.
In the past 5 years MDGL always reported negative net income.
MDGL had a negative operating cash flow in each of the past 5 years.
MDGL Yearly Net Income VS EBIT VS OCF VS FCFMDGL Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 -100M -200M -300M -400M

1.2 Ratios

The Return On Assets of MDGL (-21.22%) is better than 74.20% of its industry peers.
The Return On Equity of MDGL (-46.21%) is better than 67.42% of its industry peers.
Industry RankSector Rank
ROA -21.22%
ROE -46.21%
ROIC N/A
ROA(3y)-61.5%
ROA(5y)-68.68%
ROE(3y)-101.19%
ROE(5y)-102.23%
ROIC(3y)N/A
ROIC(5y)N/A
MDGL Yearly ROA, ROE, ROICMDGL Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 500 -500 -1K -1.5K

1.3 Margins

Looking at the Gross Margin, with a value of 95.25%, MDGL belongs to the top of the industry, outperforming 95.10% of the companies in the same industry.
The Profit Margin and Operating Margin are not available for MDGL so they could not be analyzed.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM 95.25%
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
MDGL Yearly Profit, Operating, Gross MarginsMDGL Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 -100 -200

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4

2. Health

2.1 Basic Checks

MDGL does not have a ROIC to compare to the WACC, probably because it is not profitable.
MDGL has more shares outstanding than it did 1 year ago.
MDGL has more shares outstanding than it did 5 years ago.
Compared to 1 year ago, MDGL has an improved debt to assets ratio.
MDGL Yearly Shares OutstandingMDGL Yearly Shares OutstandingYearly Shares Outstanding 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 5M 10M 15M 20M
MDGL Yearly Total Debt VS Total AssetsMDGL Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 200M 400M 600M 800M 1B

2.2 Solvency

MDGL has an Altman-Z score of 9.12. This indicates that MDGL is financially healthy and has little risk of bankruptcy at the moment.
MDGL has a Altman-Z score of 9.12. This is amongst the best in the industry. MDGL outperforms 80.23% of its industry peers.
MDGL has a Debt/Equity ratio of 0.54. This is a neutral value indicating MDGL is somewhat dependend on debt financing.
The Debt to Equity ratio of MDGL (0.54) is worse than 72.88% of its industry peers.
Industry RankSector Rank
Debt/Equity 0.54
Debt/FCF N/A
Altman-Z 9.12
ROIC/WACCN/A
WACC8.74%
MDGL Yearly LT Debt VS Equity VS FCFMDGL Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 0 200M -200M 400M -400M 600M

2.3 Liquidity

A Current Ratio of 3.44 indicates that MDGL has no problem at all paying its short term obligations.
MDGL's Current ratio of 3.44 is on the low side compared to the rest of the industry. MDGL is outperformed by 60.08% of its industry peers.
A Quick Ratio of 3.26 indicates that MDGL has no problem at all paying its short term obligations.
With a Quick ratio value of 3.26, MDGL perfoms like the industry average, outperforming 40.30% of the companies in the same industry.
Industry RankSector Rank
Current Ratio 3.44
Quick Ratio 3.26
MDGL Yearly Current Assets VS Current LiabilitesMDGL Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 200M 400M 600M 800M 1B

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5

3. Growth

3.1 Past

The Earnings Per Share has grown by an impressive 48.60% over the past year.
MDGL shows a strong growth in Revenue. In the last year, the Revenue has grown by 864.21%.
EPS 1Y (TTM)48.6%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-0.81%
Revenue 1Y (TTM)864.21%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%362.03%

3.2 Future

Based on estimates for the next years, MDGL will show a very strong growth in Earnings Per Share. The EPS will grow by 34.00% on average per year.
MDGL is expected to show a strong growth in Revenue. In the coming years, the Revenue will grow by 85.75% yearly.
EPS Next Y54.07%
EPS Next 2Y46.04%
EPS Next 3Y43.78%
EPS Next 5Y34%
Revenue Next Year444.3%
Revenue Next 2Y188.74%
Revenue Next 3Y129.31%
Revenue Next 5Y85.75%

3.3 Evolution

MDGL Yearly Revenue VS EstimatesMDGL Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2014 2024 2025 2026 2027 2028 2029 2030 2031 2032 1B 2B 3B 4B 5B
MDGL Yearly EPS VS EstimatesMDGL Yearly EPS VS EstimatesYearly EPS VS Estimates 2014 2016 2018 2020 2022 2024 2026 2028 2030 2032 0 20 -20 40 60

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2

4. Valuation

4.1 Price/Earnings Ratio

The Price/Earnings Ratio is negative for MDGL. In the last year negative earnings were reported.
With a Price/Forward Earnings ratio of 194.70, MDGL can be considered very expensive at the moment.
Based on the Price/Forward Earnings ratio, MDGL is valued cheaper than 87.76% of the companies in the same industry.
MDGL's Price/Forward Earnings ratio indicates a rather expensive valuation when compared to the S&P500 average which is at 23.78.
Industry RankSector Rank
PE N/A
Fwd PE 194.7
MDGL Price Earnings VS Forward Price EarningsMDGL Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 50 100 150

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
MDGL Per share dataMDGL EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 10 -10 20 30

4.3 Compensation for Growth

The high PEG Ratio(NY), which compensates the Price/Earnings for growth, indicates an expensive valuation of the company.
MDGL's earnings are expected to grow with 43.78% in the coming years. This may justify a more expensive valuation.
PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y46.04%
EPS Next 3Y43.78%

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0

5. Dividend

5.1 Amount

No dividends for MDGL!.
Industry RankSector Rank
Dividend Yield N/A

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MADRIGAL PHARMACEUTICALS INC

NASDAQ:MDGL (12/12/2025, 8:00:00 PM)

After market: 580.5 +9.06 (+1.59%)

571.44

+0.11 (+0.02%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)11-04 2025-11-04/bmo
Earnings (Next)02-24 2026-02-24/amc
Inst Owners96.81%
Inst Owner Change2.02%
Ins Owners0.95%
Ins Owner Change2.36%
Market Cap12.98B
Revenue(TTM)740.64M
Net Income(TTM)-289.13M
Analysts83.48
Price Target573.11 (0.29%)
Short Float %18.03%
Short Ratio10.83
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)1
Avg EPS beat(2)-42.41%
Min EPS beat(2)-133.61%
Max EPS beat(2)48.79%
EPS beat(4)3
Avg EPS beat(4)-8.49%
Min EPS beat(4)-133.61%
Max EPS beat(4)48.79%
EPS beat(8)5
Avg EPS beat(8)-2.09%
EPS beat(12)6
Avg EPS beat(12)-1.21%
EPS beat(16)8
Avg EPS beat(16)-1.44%
Revenue beat(2)2
Avg Revenue beat(2)21.21%
Min Revenue beat(2)13.88%
Max Revenue beat(2)28.53%
Revenue beat(4)4
Avg Revenue beat(4)15.85%
Min Revenue beat(4)2.78%
Max Revenue beat(4)28.53%
Revenue beat(8)N/A
Avg Revenue beat(8)N/A
Revenue beat(12)N/A
Avg Revenue beat(12)N/A
Revenue beat(16)N/A
Avg Revenue beat(16)N/A
PT rev (1m)12.42%
PT rev (3m)23.22%
EPS NQ rev (1m)83.21%
EPS NQ rev (3m)92.68%
EPS NY rev (1m)-6.15%
EPS NY rev (3m)4.8%
Revenue NQ rev (1m)-0.16%
Revenue NQ rev (3m)11.99%
Revenue NY rev (1m)8.13%
Revenue NY rev (3m)8.48%
Valuation
Industry RankSector Rank
PE N/A
Fwd PE 194.7
P/S 17.52
P/FCF N/A
P/OCF N/A
P/B 20.74
P/tB 20.99
EV/EBITDA N/A
EPS(TTM)-12.89
EYN/A
EPS(NY)2.93
Fwd EY0.51%
FCF(TTM)-7.25
FCFYN/A
OCF(TTM)-7.07
OCFYN/A
SpS32.61
BVpS27.55
TBVpS27.22
PEG (NY)N/A
PEG (5Y)N/A
Graham NumberN/A
Profitability
Industry RankSector Rank
ROA -21.22%
ROE -46.21%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM 95.25%
FCFM N/A
ROA(3y)-61.5%
ROA(5y)-68.68%
ROE(3y)-101.19%
ROE(5y)-102.23%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score4
Asset Turnover0.54
Health
Industry RankSector Rank
Debt/Equity 0.54
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 274.34%
Cap/Sales 0.55%
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 3.44
Quick Ratio 3.26
Altman-Z 9.12
F-Score4
WACC8.74%
ROIC/WACCN/A
Cap/Depr(3y)305.68%
Cap/Depr(5y)207.7%
Cap/Sales(3y)N/A
Cap/Sales(5y)N/A
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)48.6%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-0.81%
EPS Next Y54.07%
EPS Next 2Y46.04%
EPS Next 3Y43.78%
EPS Next 5Y34%
Revenue 1Y (TTM)864.21%
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%362.03%
Revenue Next Year444.3%
Revenue Next 2Y188.74%
Revenue Next 3Y129.31%
Revenue Next 5Y85.75%
EBIT growth 1Y43.9%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year46.19%
EBIT Next 3Y41.27%
EBIT Next 5YN/A
FCF growth 1Y45.72%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y46.97%
OCF growth 3YN/A
OCF growth 5YN/A

MADRIGAL PHARMACEUTICALS INC / MDGL FAQ

What is the ChartMill fundamental rating of MADRIGAL PHARMACEUTICALS INC (MDGL) stock?

ChartMill assigns a fundamental rating of 3 / 10 to MDGL.


What is the valuation status of MADRIGAL PHARMACEUTICALS INC (MDGL) stock?

ChartMill assigns a valuation rating of 2 / 10 to MADRIGAL PHARMACEUTICALS INC (MDGL). This can be considered as Overvalued.


Can you provide the profitability details for MADRIGAL PHARMACEUTICALS INC?

MADRIGAL PHARMACEUTICALS INC (MDGL) has a profitability rating of 2 / 10.


Can you provide the expected EPS growth for MDGL stock?

The Earnings per Share (EPS) of MADRIGAL PHARMACEUTICALS INC (MDGL) is expected to grow by 54.07% in the next year.