SPYRE THERAPEUTICS INC (SYRE) Stock Price & Overview

NASDAQ:SYRE • US00773J2024

Current stock price

51.77 USD
-0.21 (-0.4%)
At close:
50.12 USD
-1.65 (-3.19%)
Pre-Market:

The current stock price of SYRE is 51.77 USD. Today SYRE is down by -0.4%. In the past month the price increased by 24.75%. In the past year, price increased by 323.65%.

SYRE Key Statistics

52-Week Range12.04 - 54.39
Current SYRE stock price positioned within its 52-week range.
1-Month Range39 - 54.39
Current SYRE stock price positioned within its 1-month range.
Market Cap
4.066B
P/E
N/A
Fwd P/E
N/A
EPS (TTM)
-2.22
Dividend Yield
N/A

SYRE Stock Performance

Today
-0.4%
1 Week
+5.87%
1 Month
+24.75%
3 Months
+69.13%
Longer-term
6 Months +170.48%
1 Year +323.65%
2 Years +56.74%
3 Years N/A
5 Years N/A
10 Years N/A

SYRE Stock Chart

SPYRE THERAPEUTICS INC / SYRE Daily stock chart

SYRE Technical Analysis

ChartMill assigns a technical rating of 10 / 10 to SYRE. When comparing the yearly performance of all stocks, SYRE is one of the better performing stocks in the market, outperforming 98.48% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

SYRE Fundamental Analysis

ChartMill assigns a fundamental rating of 3 / 10 to SYRE. While SYRE has a great health rating, there are worries on its profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

SYRE Earnings

Next Earnings DateMay 6, 2026
Last Earnings DateFeb 19, 2026
PeriodQ4 / 2025
EPS Reported-$0.70
Revenue Reported
EPS Surprise 11.43%
Revenue Surprise %

SYRE Forecast & Estimates

21 analysts have analysed SYRE and the average price target is 62 USD. This implies a price increase of 19.76% is expected in the next year compared to the current price of 51.77.


Analysts
Analysts89.52
Price Target62 (19.76%)
EPS Next Y-34.9%
Revenue Next YearN/A

SYRE Groups

Sector & Classification

SYRE Financial Highlights

Over the last trailing twelve months SYRE reported a non-GAAP Earnings per Share(EPS) of -2.22. The EPS increased by 47.52% compared to the year before.


Income Statements
Revenue(TTM)N/A
Net Income(TTM)-148.79M
Industry RankSector Rank
PM (TTM) N/A
ROA -29.49%
ROE -32.69%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%13.58%
Sales Q2Q%N/A
EPS 1Y (TTM)47.52%
Revenue 1Y (TTM)N/A

SYRE Ownership

Ownership
Inst Owners100.75%
Shares78.54M
Float70.10M
Ins Owners6.66%
Short Float %14.26%
Short Ratio13.55

About SYRE

Company Profile

SYRE logo image Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. The company is headquartered in Waltham, Massachusetts and currently employs 102 full-time employees. The company went IPO on 2016-04-07. Its pipeline includes investigational extended half-life antibodies targeting a4b7, TL1A, and IL-23. Its pipeline programs include SPY003, SPY004, SPY130, SPY230, SPY002, SPY001, and SPY120. Its advanced product candidate, SPY001, is a fully human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4b7 integrin being developed for the treatment of IBD. Its co-lead program, SPY002, has nominated two fully human mAb candidates designed to bind to tumor necrosis factor-like ligand 1A (TL1A), both of which are in preclinical development for the treatment of IBD. SPY003 is a preclinical-stage program designed to bind to Interleukin 23 (IL-23) and incorporates half-life extending modifications.

Company Info

IPO: 2016-04-07

SPYRE THERAPEUTICS INC

221 Crescent Street, Suite 105

Waltham MASSACHUSETTS US

Employees: 102

SYRE Company Website

SYRE Investor Relations

Phone: 16176515940.0

SPYRE THERAPEUTICS INC / SYRE FAQ

What does SPYRE THERAPEUTICS INC do?

Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. The company is headquartered in Waltham, Massachusetts and currently employs 102 full-time employees. The company went IPO on 2016-04-07. Its pipeline includes investigational extended half-life antibodies targeting a4b7, TL1A, and IL-23. Its pipeline programs include SPY003, SPY004, SPY130, SPY230, SPY002, SPY001, and SPY120. Its advanced product candidate, SPY001, is a fully human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4b7 integrin being developed for the treatment of IBD. Its co-lead program, SPY002, has nominated two fully human mAb candidates designed to bind to tumor necrosis factor-like ligand 1A (TL1A), both of which are in preclinical development for the treatment of IBD. SPY003 is a preclinical-stage program designed to bind to Interleukin 23 (IL-23) and incorporates half-life extending modifications.


What is the stock price of SPYRE THERAPEUTICS INC today?

The current stock price of SYRE is 51.77 USD. The price decreased by -0.4% in the last trading session.


Does SYRE stock pay dividends?

SYRE does not pay a dividend.


How is the ChartMill rating for SPYRE THERAPEUTICS INC?

SYRE has a ChartMill Technical rating of 10 out of 10 and a ChartMill Fundamental rating of 3 out of 10.


Would investing in SPYRE THERAPEUTICS INC be a good decision?

This depends on your investment goals. Check the Technical and Fundamental Analysis tabs for insights on SYRE.


What is the outstanding short interest for SPYRE THERAPEUTICS INC?

The outstanding short interest for SPYRE THERAPEUTICS INC (SYRE) is 14.26% of its float.