Logo image of SYRE

SPYRE THERAPEUTICS INC (SYRE) Stock Price, Forecast & Analysis

USA - Nasdaq - NASDAQ:SYRE - US00773J2024 - Common Stock

29.48 USD
+0.28 (+0.96%)
Last: 11/26/2025, 2:27:33 PM

SYRE Key Statistics, Chart & Performance

Key Statistics
Market Cap2.29B
Revenue(TTM)N/A
Net Income(TTM)-208.02M
Shares77.59M
Float71.15M
52 Week High29.5
52 Week Low10.91
Yearly DividendN/A
Dividend YieldN/A
EPS(TTM)-2.33
PEN/A
Fwd PEN/A
Earnings (Next)02-25 2026-02-25/amc
IPO2016-04-07
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology


SYRE short term performance overview.The bars show the price performance of SYRE in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 20 40 60 80

SYRE long term performance overview.The bars show the price performance of SYRE in the last 1, 2 and 3 years. 1 year 2 years 3 years 10 20 30 40 50

The current stock price of SYRE is 29.48 USD. In the past month the price increased by 18.51%. In the past year, price increased by 2.71%.

SPYRE THERAPEUTICS INC / SYRE Daily stock chart

SYRE Latest News, Press Relases and Analysis

SYRE Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
Full List
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TA
FA
PE
Market Cap
ABBV ABBVIE INC 24.08 402.04B
AMGN AMGEN INC 15.76 185.57B
GILD GILEAD SCIENCES INC 15.6 158.53B
VRTX VERTEX PHARMACEUTICALS INC 24.87 110.69B
REGN REGENERON PHARMACEUTICALS 17.49 83.43B
ALNY ALNYLAM PHARMACEUTICALS INC 875.33 58.52B
INSM INSMED INC N/A 43.37B
NTRA NATERA INC N/A 32.72B
BIIB BIOGEN INC 10.93 26.83B
UTHR UNITED THERAPEUTICS CORP 18.64 22.25B
INCY INCYTE CORP 16.57 20.77B
EXAS EXACT SCIENCES CORP N/A 19.23B

About SYRE

Company Profile

SYRE logo image Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. The company is headquartered in Waltham, Massachusetts and currently employs 87 full-time employees. The company went IPO on 2016-04-07. Its pipeline includes investigational extended half-life antibodies targeting a4b7, TL1A, and IL-23. Its pipeline programs include SPY003, SPY004, SPY130, SPY230, SPY002, SPY001, and SPY120. Its advanced product candidate, SPY001, is a fully human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4b7 integrin being developed for the treatment of IBD. Its co-lead program, SPY002, has nominated two fully human mAb candidates designed to bind to tumor necrosis factor-like ligand 1A (TL1A), both of which are in preclinical development for the treatment of IBD. SPY003 is a preclinical-stage program designed to bind to Interleukin 23 (IL-23) and incorporates half-life extending modifications.

Company Info

SPYRE THERAPEUTICS INC

221 Crescent Street, Suite 105

Waltham MASSACHUSETTS US

Employees: 65

SYRE Company Website

SYRE Investor Relations

Phone: 16176515940.0

SPYRE THERAPEUTICS INC / SYRE FAQ

What does SPYRE THERAPEUTICS INC do?

Spyre Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in the development of next-generation human enzyme therapeutics as disruptive solutions for rare and other high-burden diseases. The company is headquartered in Waltham, Massachusetts and currently employs 87 full-time employees. The company went IPO on 2016-04-07. Its pipeline includes investigational extended half-life antibodies targeting a4b7, TL1A, and IL-23. Its pipeline programs include SPY003, SPY004, SPY130, SPY230, SPY002, SPY001, and SPY120. Its advanced product candidate, SPY001, is a fully human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4b7 integrin being developed for the treatment of IBD. Its co-lead program, SPY002, has nominated two fully human mAb candidates designed to bind to tumor necrosis factor-like ligand 1A (TL1A), both of which are in preclinical development for the treatment of IBD. SPY003 is a preclinical-stage program designed to bind to Interleukin 23 (IL-23) and incorporates half-life extending modifications.


What is the current price of SYRE stock?

The current stock price of SYRE is 29.48 USD. The price increased by 0.96% in the last trading session.


What is the dividend status of SPYRE THERAPEUTICS INC?

SYRE does not pay a dividend.


How is the ChartMill rating for SPYRE THERAPEUTICS INC?

SYRE has a ChartMill Technical rating of 9 out of 10 and a ChartMill Fundamental rating of 3 out of 10.


What sector and industry does SPYRE THERAPEUTICS INC belong to?

SPYRE THERAPEUTICS INC (SYRE) operates in the Health Care sector and the Biotechnology industry.


What is SPYRE THERAPEUTICS INC worth?

SPYRE THERAPEUTICS INC (SYRE) has a market capitalization of 2.29B USD. This makes SYRE a Mid Cap stock.


SYRE Technical Analysis

ChartMill assigns a technical rating of 9 / 10 to SYRE. When comparing the yearly performance of all stocks, SYRE is one of the better performing stocks in the market, outperforming 92.17% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

SYRE Fundamental Analysis

ChartMill assigns a fundamental rating of 3 / 10 to SYRE. No worries on liquidiy or solvency for SYRE as it has an excellent financial health rating, but there are worries on the profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

SYRE Financial Highlights

Over the last trailing twelve months SYRE reported a non-GAAP Earnings per Share(EPS) of -2.33. The EPS increased by 68.81% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -34.19%
ROE -40.17%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%88.97%
Sales Q2Q%N/A
EPS 1Y (TTM)68.81%
Revenue 1Y (TTM)-100%

SYRE Forecast & Estimates

19 analysts have analysed SYRE and the average price target is 53.69 USD. This implies a price increase of 82.12% is expected in the next year compared to the current price of 29.48.

For the next year, analysts expect an EPS growth of 32.57% and a revenue growth -100% for SYRE


Analysts
Analysts88.42
Price Target53.69 (82.12%)
EPS Next Y32.57%
Revenue Next Year-100%

SYRE Ownership

Ownership
Inst Owners104.27%
Ins Owners8.7%
Short Float %17.57%
Short Ratio13.03