UPSTREAM BIO INC (UPB) Stock Price & Overview
NASDAQ:UPB • US91678A1079
Current stock price
The current stock price of UPB is 9.5 USD. Today UPB is up by 2.04%. In the past month the price increased by 23.86%. In the past year, price increased by 55.74%.
UPB Key Statistics
- Market Cap
- 513.38M
- P/E
- N/A
- Fwd P/E
- N/A
- EPS (TTM)
- -3.47
- Dividend Yield
- N/A
UPB Stock Performance
UPB Stock Chart
UPB Technical Analysis
ChartMill assigns a technical rating of 1 / 10 to UPB. When comparing the yearly performance of all stocks, UPB is a bad performer in the overall market: 74.38% of all stocks are doing better.
UPB Fundamental Analysis
ChartMill assigns a fundamental rating of 3 / 10 to UPB. UPB has a great financial health rating, but its profitability evaluates not so good.
UPB Earnings
On March 18, 2026 UPB reported an EPS of -0.63 and a revenue of 683.00K. The company beat EPS expectations (20.23% surprise) and beat revenue expectations (4.84% surprise).
UPB Forecast & Estimates
12 analysts have analysed UPB and the average price target is 49.47 USD. This implies a price increase of 420.74% is expected in the next year compared to the current price of 9.5.
For the next year, analysts expect an EPS growth of 67.9% and a revenue growth 25.46% for UPB
UPB Groups
Sector & Classification
UPB Financial Highlights
Over the last trailing twelve months UPB reported a non-GAAP Earnings per Share(EPS) of -3.47. The EPS decreased by -99.7% compared to the year before.
| Industry Rank | Sector Rank | ||
|---|---|---|---|
| PM (TTM) | N/A | ||
| ROA | -31.38% | ||
| ROE | -32.43% | ||
| Debt/Equity | 0 |
UPB Ownership
UPB Competitors/Peers
| Symbol | Company Name | Technical Rating | Fundamental Rating | FPE | Market Cap |
|---|---|---|---|---|---|
| ABBV | ABBVIE INC | 14.07 | 380.121B | ||
| AMGN | AMGEN INC | 15.24 | 190.443B | ||
| GILD | GILEAD SCIENCES INC | 15.81 | 174.171B | ||
| VRTX | VERTEX PHARMACEUTICALS INC | 22.63 | 113.617B | ||
| REGN | REGENERON PHARMACEUTICALS | 16.3 | 82.171B | ||
| ALNY | ALNYLAM PHARMACEUTICALS INC | 42.73 | 43.596B | ||
| INSM | INSMED INC | N/A | 35.536B | ||
| NTRA | NATERA INC | N/A | 28.801B | ||
| BIIB | BIOGEN INC | 11.03 | 26.972B | ||
| UTHR | UNITED THERAPEUTICS CORP | 18.91 | 24.995B | ||
| MRNA | MODERNA INC | N/A | 19.759B | ||
| RVMD | REVOLUTION MEDICINES INC | N/A | 19.548B | ||
| INCY | INCYTE CORP | 12.53 | 18.767B |
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About UPB
Company Profile
Upstream Bio, Inc. is a clinical-stage biotechnology company, which engages in the development of treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. The company is headquartered in Waltham, Massachusetts and currently employs 52 full-time employees. The company went IPO on 2024-10-11. The firm is developing verekitug, the only known antagonist in clinical development, that targets the receptor for thymic stromal lymphopoietin (TSLP), a cytokine which is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune mediated diseases. The company has advanced this highly potent monoclonal antibody into separate phase II trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and plans to initiate development in chronic obstructive pulmonary disease. TSLP is a member of a class of epithelial cytokines, also including IL-25 and IL-33, commonly referred to as alarmins. TSLP is primarily produced by epithelial cells, especially in the lung, gastrointestinal tract and skin.
Company Info
IPO: 2024-10-11
UPSTREAM BIO INC
890 Winter Street, Suite 200
Waltham MASSACHUSETTS US
Employees: 52
Phone: 17812082466
UPSTREAM BIO INC / UPB FAQ
What does UPB do?
Upstream Bio, Inc. is a clinical-stage biotechnology company, which engages in the development of treatments for inflammatory diseases, with an initial focus on severe respiratory disorders. The company is headquartered in Waltham, Massachusetts and currently employs 52 full-time employees. The company went IPO on 2024-10-11. The firm is developing verekitug, the only known antagonist in clinical development, that targets the receptor for thymic stromal lymphopoietin (TSLP), a cytokine which is a clinically validated driver of inflammatory response positioned upstream of multiple signaling cascades that affect a variety of immune mediated diseases. The company has advanced this highly potent monoclonal antibody into separate phase II trials for the treatment of severe asthma and chronic rhinosinusitis with nasal polyps and plans to initiate development in chronic obstructive pulmonary disease. TSLP is a member of a class of epithelial cytokines, also including IL-25 and IL-33, commonly referred to as alarmins. TSLP is primarily produced by epithelial cells, especially in the lung, gastrointestinal tract and skin.
What is the current price of UPB stock?
The current stock price of UPB is 9.5 USD. The price increased by 2.04% in the last trading session.
Does UPSTREAM BIO INC pay dividends?
UPB does not pay a dividend.
What is the ChartMill technical and fundamental rating of UPB stock?
UPB has a ChartMill Technical rating of 1 out of 10 and a ChartMill Fundamental rating of 3 out of 10.
What is the GICS sector and industry of UPB stock?
UPSTREAM BIO INC (UPB) operates in the Health Care sector and the Biotechnology industry.
What is UPSTREAM BIO INC worth?
UPSTREAM BIO INC (UPB) has a market capitalization of 513.38M USD. This makes UPB a Small Cap stock.
What is the next earnings date for UPB stock?
UPSTREAM BIO INC (UPB) will report earnings on 2026-05-04.