UPSTREAM BIO INC (UPB) Forecast, Price Target & Analyst Ratings
NASDAQ:UPB • US91678A1079
9.44 USD
+0.08 (+0.85%)
At close: Mar 12, 2026
9.35 USD
-0.09 (-0.95%)
After Hours: 3/12/2026, 5:48:58 PM
View the latest analyst price targets, stock forecast, EPS estimates, revenue projections, revisions, full estimates, rating distribution and upgrades/downgrades for UPSTREAM BIO INC (UPB).
Forecast Snapshot
Consensus Price Target
$49.47
+ 424.05% Upside
Next Earnings Forecast
Release DateMar 18, 2026
PeriodQ4 / 2025
EPS Estimate-$0.71
Revenue Estimate614.413K
ChartMill Buy Consensus
81.67%
Weighted Analyst Rating Score
Price Target Details & History
Consensus Price Target and Range
Mean target
$49.47
Upside
+ 424.05%
From current price of $9.44 to mean target of $49.47, Based on 12 analyst forecasts
Low
$35.35
Median
$45.90
High
$78.75
Price Target Revisions
1 Month
0.00%
3 Months
-3.00%
Price Target Summary
12 Wall Street analysts provided a forecast for the next 12 months for UPB. The average price target is 49.47 USD. This implies a price increase of 424.05% is expected in the next year compared to the current price of 9.44.
The average price target has been revised downward by 3% in the past 3 months.
Analyst Ratings & History
Current Analyst Ratings
Analyst Ratings History
Analyst Ratings Consensus
ChartMill Buy Consensus
81.67%
UPB was analyzed by 12 analysts. The buy percentage consensus is at 82. So analysts seem to be very confident about UPB.
In the previous month the buy percentage consensus was at a similar level.
UPB was analyzed by 12 analysts, which should be a sufficient number of analysts to have a meaningful average consensus rating.
Recent Upgrades & Downgrades
| Date | Firm | Action | From → To |
|---|---|---|---|
| 2025-12-18 | Mizuho | Initiate | Outperform |
| 2025-12-02 | LifeSci Capital | Initiate | Outperform |
| 2025-11-18 | Evercore ISI Group | Initiate | Outperform |
| 2025-10-14 | Truist Securities | Initiate | Buy |
| 2024-11-05 | TD Cowen | Initiate | Buy |
| 2024-11-05 | William Blair | Initiate | Outperform |
| 2024-11-05 | JP Morgan | Initiate | Overweight |
| 2024-11-05 | Piper Sandler | Initiate | Overweight |
Next Earnings Forecast Details
Next Earnings Details
Release DateMar 18, 2026
PeriodQ4 / 2025
EPS Estimate-$0.71
Revenue Estimate614.413K
Revenue Q2Q0.23%
EPS Q2Q55.61%
Number of Analysts9
Next Earnings Revisions
Revenue (1 Month)
0.00%
Revenue (3 Months)
-0.68%
EPS (1 Month)
0.00%
EPS (3 Months)
2.41%
Next Earnings Summary
UPB is expected to report earnings on 3/18/2026. The consensus EPS estimate for the next earnings is -0.71 USD and the consensus revenue estimate is 614.41K USD.
The next earnings revenue estimate has been revised downward by 0.68% in the past 3 months.
Full Analyst Estimates
Yearly Earnings Per Share (EPS), Revenue, EBIT, EBITDA and Operating Margin Analyst Estimates
| 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | 2029 | 2030 | 2031 | 2032 | 2033 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Revenue YoY % growth | 1.212M | 2.38M 96.37% | 2.37M -0.42% | 2.794M 17.89% | 1.549M -44.56% | 1.639M 5.81% | 5.705M 248.08% | 8.507M 49.11% | 92.697M 989.66% | 239.57M 158.44% | 463.61M 93.52% | 842.56M 81.74% | |
| EBITDA YoY % growth | -23.902M | -40.054M -67.58% | -77.675M -93.93% | -154.53M -98.94% | -183.82M -18.95% | -200.99M -9.34% | N/A | N/A | N/A | N/A | N/A | N/A | |
| EBIT YoY % growth | -23.909M | -40.114M -67.78% | -77.764M -93.86% | -158.196M -103.43% | -199.783M -26.29% | -216.822M -8.53% | -296.948M -36.95% | -260.872M 12.15% | -229.971M 11.85% | -114.72M 50.12% | 59.985M 152.29% | 368.83M 514.87% | |
| Operating Margin | -1,972.69% | -1,685.46% | -3,281.18% | -5,661.98% | -12,897.53% | -13,228.94% | -5,205.05% | -3,066.55% | -248.09% | -47.89% | 12.94% | 43.77% | |
| EPS YoY % growth | N/A | N/A | N/A | -2.60 67.90% | -3.18 -22.08% | -3.66 -15.23% | -5.25 -43.40% | -4.01 23.61% | -3.62 9.76% | -1.55 57.20% | 1.20 177.61% | 5.43 352.10% |
All data in USD
Quarterly Earnings Per Share (EPS), Revenue, EBIT and EBITDA Analyst Estimates
| Q4 / 25 | Q1 / 26 | Q2 / 26 | Q3 / 26 | Q4 / 26 | Q1 / 27 | Q2 / 27 | Q3 / 27 | Q4 / 27 | |
|---|---|---|---|---|---|---|---|---|---|
| EPS Q2Q % growth | -0.71 55.61% | -0.77 -50.18% | -0.78 -5.37% | -0.75 -18.31% | -0.83 -17.92% | -0.59 23.52% | -0.60 23.58% | -0.61 18.70% | -0.61 27.18% |
| Revenue Q2Q % growth | 614.413K 0.23% | 451.47K -20.23% | 395.163K -57.83% | 405.263K -40.66% | 405.263K -34.04% | 747.4K 65.55% | 747.4K 89.14% | 757.5K 86.92% | 767.6K 89.41% |
| EBITDA Q2Q % growth | -39.39M -50.18% | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| EBIT Q2Q % growth | -42.656M -62.08% | -46.767M -46.09% | -50.398M -13.65% | -53.651M -41.81% | -57.178M -34.04% | N/A | N/A | N/A | N/A |
All data in USD
Yearly Earnings Per Share (EPS) and Revenue Trends vs Historical Data
Long Term Forward Growth Forecast Summary
Long Term EPS Growth (CAGR)
EPS Next 3 Year
15.69%
EPS Next 5 Year
8.52%
Long Term Revenue Growth (CAGR)
Revenue Next 3 Year
-9.71%
Revenue Next 5 Year
30.74%
Long Term EBIT Growth (CAGR)
EBIT Next 3 Year
-36.38%
EBIT Next 5 Year
N/A
UPSTREAM BIO INC / UPB Forecast FAQ
What is the price target for UPB stock?
12 analysts have analysed UPB and the average price target is 49.47 USD. This implies a price increase of 424.05% is expected in the next year compared to the current price of 9.44.
What is the next earnings date for UPB stock?
UPSTREAM BIO INC (UPB) will report earnings on 2026-03-18.
Can you provide the consensus estimates for UPSTREAM BIO INC next earnings?
The consensus EPS estimate for the next earnings of UPSTREAM BIO INC (UPB) is -0.71 USD and the consensus revenue estimate is 614.41K USD.
What is the consensus rating for UPB stock?
The consensus rating for UPSTREAM BIO INC (UPB) is 81.6667 / 100 . This indicates that analysts generally have a positive outlook on the stock.