UPSTREAM BIO INC (UPB) Forecast, Price Target & Analyst Ratings

NASDAQ:UPBUS91678A1079

Current stock price

10.42 USD
+0.58 (+5.89%)
At close:
10.42 USD
0 (0%)
Pre-Market:

Analyst forecast overview

View the latest analyst price targets, stock forecast, EPS estimates, revenue projections, revisions, full estimates, rating distribution and upgrades/downgrades for UPSTREAM BIO INC (UPB).

Forecast Snapshot

Consensus Price Target

Price Target
$49.47
+ 374.76% Upside

Next Earnings Forecast

Earnings Estimate
Release Date
May 4, 2026
Period
Q1 / 2026
EPS Estimate
-$0.77
Revenue Estimate
446.42K

ChartMill Buy Consensus

Rating
80.00%
Weighted Analyst Rating Score

Price Target Details & History

Consensus Price Target and Range

Mean target
$49.47
Upside
+ 374.76%
From current price of $10.42 to mean target of $49.47, Based on 12 analyst forecasts
Low
$35.35
Median
$45.90
High
$78.75

Price Target Revisions

1 Month
0.00%
3 Months
1.04%

Price Target Summary

12 Wall Street analysts provided a forecast for the next 12 months for UPB. The average price target is 49.47 USD. This implies a price increase of 374.76% is expected in the next year compared to the current price of 10.42.
The average price target has been revised upward by 1.04% in the past 3 months.

Analyst Ratings & History

Current Analyst Ratings

UPB Current Analyst RatingUPB Current Analyst Buy, Sell and Hold Ratings.Current Analyst Rating Strong Buy Buy Hold Sell Strong Sell 2 4 6

Analyst Ratings History

UPB Historical Analyst RatingsUPB Historical Analyst Buy, Sell and Hold Ratings and number of analysts.Historical Monthly Analyst Rating -16 -14 -12 -10 -8 -6 -4 -2 0 2 4 6 8 10

Analyst Ratings Consensus

ChartMill Buy Consensus
80.00%
UPB was analyzed by 12 analysts. The buy percentage consensus is at 80. So analysts seem to be have mildly positive about UPB.
In the previous month the buy percentage consensus was at a similar level.
UPB was analyzed by 12 analysts, which should be a sufficient number of analysts to have a meaningful average consensus rating.

Recent Upgrades & Downgrades

DateFirmActionFrom → To
2026-03-27Evercore ISI GroupDowngrade Outperform -> In-Line
2025-12-18MizuhoInitiate Outperform
2025-12-02LifeSci CapitalInitiate Outperform
2025-11-18Evercore ISI GroupInitiate Outperform
2025-10-14Truist SecuritiesInitiate Buy
2024-11-05TD CowenInitiate Buy
2024-11-05William BlairInitiate Outperform
2024-11-05JP MorganInitiate Overweight
2024-11-05Piper SandlerInitiate Overweight

Next Earnings Forecast Details

Next Earnings Details

Release Date
May 4, 2026
Period
Q1 / 2026
EPS Estimate
-$0.77
Revenue Estimate
446.42K
Revenue Q2Q
-21.13%
EPS Q2Q
-50.26%
Number of Analysts
9

Next Earnings Revisions

Revenue (1 Month)
0.00%
Revenue (3 Months)
0.00%
EPS (1 Month)
0.00%
EPS (3 Months)
-2.54%

Next Earnings Summary

UPB is expected to report earnings on 5/4/2026. The consensus EPS estimate for the next earnings is -0.77 USD and the consensus revenue estimate is 446.42K USD.
The next earnings revenue estimate has been revised downward by 0% in the past 3 months.

Full Analyst Estimates 2026 - 2033

Yearly Earnings Per Share (EPS), Revenue, EBIT, EBITDA and Operating Margin Analyst Estimates

2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 2033
Revenue
YoY % growth
UPB revenue by date.UPB revenue by date.
1.212M2.38M
96.37%
2.37M
-0.42%
2.794M
17.89%
1.507M
-46.06%
1.719M
14.07%
5.729M
233.28%
8.507M
48.49%
92.697M
989.66%
239.57M
158.44%
463.61M
93.52%
842.56M
81.74%
EBITDA
YoY % growth
UPB ebitda by date.UPB ebitda by date.
-23.902M-40.054M
-67.58%
-77.675M
-93.93%
-154.53M
-98.94%
-183.82M
-18.95%
-200.99M
-9.34%
N/AN/AN/AN/AN/AN/A
EBIT
YoY % growth
UPB ebit by date.UPB ebit by date.
-23.909M-40.114M
-67.78%
-77.764M
-93.86%
-158.196M
-103.43%
-199.783M
-26.29%
-216.822M
-8.53%
-296.948M
-36.95%
-260.872M
12.15%
-229.971M
11.85%
-114.72M
50.12%
59.985M
152.29%
368.83M
514.87%
Operating Margin
UPB operating margin by date.UPB operating margin by date.
-1,972.69%-1,685.46%-3,281.18%-5,661.98%-13,256.99%-12,613.28%-5,183.24%-3,066.55%-248.09%-47.89%12.94%43.77%
EPS
YoY % growth
UPB eps by date.UPB eps by date.
N/AN/AN/A-2.60
67.12%
-3.18
-19.19%
-3.66
-15.23%
-5.25
-43.40%
-4.01
23.61%
-3.62
9.76%
-1.55
57.20%
1.20
177.61%
5.43
352.10%

All data in USD

Quarterly Earnings Per Share (EPS), Revenue, EBIT and EBITDA Analyst Estimates

Q1 / 26 Q2 / 26 Q3 / 26 Q4 / 26 Q1 / 27 Q2 / 27 Q3 / 27 Q4 / 27
EPS
Q2Q % growth
-0.77
-50.26%
-0.76
-2.71%
-0.75
-19.44%
-0.81
-3.09%
-0.90
-17.30%
-0.95
-24.92%
-0.98
-30.87%
-1.06
-31.05%
Revenue
Q2Q % growth
446.42K
-21.13%
446.42K
-52.36%
448.44K
-34.34%
468.64K
-29.84%
747.4K
67.42%
747.4K
67.42%
757.5K
68.92%
767.6K
63.79%
EBITDA
Q2Q % growth
N/AN/AN/AN/AN/AN/AN/AN/A
EBIT
Q2Q % growth
-45.196M
-41.18%
-47.304M
-6.67%
-49.262M
-30.21%
-51.204M
-20.04%
N/AN/AN/AN/A

All data in USD

Yearly Earnings Per Share (EPS) and Revenue Trends vs Historical Data

UPB Yearly Revenue VS EstimatesUPB Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 2033 200M 400M 600M 800M
UPB Yearly EPS VS EstimatesUPB Yearly EPS VS EstimatesYearly EPS VS Estimates 2024 2025 2026 2027 2028 2029 2030 2031 2032 2033 0 2 -2 4 -4 -6 -8

Long Term Forward Growth Forecast Summary

Long Term EPS Growth (CAGR)

EPS Next 3 Year
-25.35%
EPS Next 5 Year
-6.31%

Long Term Revenue Growth (CAGR)

Revenue Next 3 Year
27.04%
Revenue Next 5 Year
101.45%

Long Term EBIT Growth (CAGR)

EBIT Next 3 Year
-36.38%
EBIT Next 5 Year
N/A

UPSTREAM BIO INC / UPB Forecast FAQ

What is the price target for UPB stock?

12 analysts have analysed UPB and the average price target is 49.47 USD. This implies a price increase of 374.76% is expected in the next year compared to the current price of 10.42.

What is the next earnings date for UPB stock?

UPSTREAM BIO INC (UPB) will report earnings on 2026-05-04.

What are the consensus estimates for UPSTREAM BIO INC (UPB) next earnings?

The consensus EPS estimate for the next earnings of UPSTREAM BIO INC (UPB) is -0.77 USD and the consensus revenue estimate is 446.42K USD.

What is the expected long term growth rate for UPSTREAM BIO INC (UPB)?

The expected long term growth rate for UPSTREAM BIO INC (UPB) is 27.04%.