Logo image of SPRB

SPRUCE BIOSCIENCES INC (SPRB) Stock Price, Forecast & Analysis

USA - Nasdaq - NASDAQ:SPRB - US85209E2081 - Common Stock

79.99 USD
+6.29 (+8.53%)
Last: 1/9/2026, 8:27:47 PM

SPRB Key Statistics, Chart & Performance

Key Statistics
Market Cap85.59M
Revenue(TTM)697.00K
Net Income(TTM)-47.88M
Shares1.07M
Float980.00K
52 Week High240
52 Week Low0.08
Yearly DividendN/A
Dividend Yield0%
EPS(TTM)-84.83
PEN/A
Fwd PEN/A
Earnings (Next)04-13 2026-04-13/amc
IPO2020-10-09
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology


SPRB short term performance overview.The bars show the price performance of SPRB in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 0 5K 10K 15K

SPRB long term performance overview.The bars show the price performance of SPRB in the last 1, 2 and 3 years. 1 year 2 years 3 years 5K 10K 15K

The current stock price of SPRB is 79.99 USD. In the past month the price decreased by -6.63%. In the past year, price increased by 16655.3%.

SPRUCE BIOSCIENCES INC / SPRB Daily stock chart

SPRB Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
Full List
Symbol
Company Name
TA
FA
PE
Market Cap
ABBV ABBVIE INC 23.29 388.96B
AMGN AMGEN INC 14.91 175.60B
GILD GILEAD SCIENCES INC 14.79 150.25B
VRTX VERTEX PHARMACEUTICALS INC 26.72 117.69B
REGN REGENERON PHARMACEUTICALS 17.7 83.72B
ALNY ALNYLAM PHARMACEUTICALS INC 780.96 52.62B
INSM INSMED INC N/A 37.53B
NTRA NATERA INC N/A 32.34B
BIIB BIOGEN INC 11.21 27.52B
UTHR UNITED THERAPEUTICS CORP 18.31 20.81B
INCY INCYTE CORP 16.65 20.98B
RVMD REVOLUTION MEDICINES INC N/A 22.94B

About SPRB

Company Profile

SPRB logo image Spruce Biosciences, Inc. is a biopharmaceutical company, which engages in developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need. The company is headquartered in South San Francisco, California and currently employs 9 full-time employees. The company went IPO on 2020-10-09. The firm has acquired an exclusive worldwide license agreement for tralesinidase alfa enzyme replacement therapy (TA-ERT) for the treatment of Sanfilippo Syndrome Type B (MPS IIIB). The TA-ERT is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) with modified human insulin-like growth factor 2 via an amino acid linker. TA-ERT is intended as an enzyme replacement therapy for the treatment of patients with MPS IIIB who lack rhNAGLU enzyme activity. The firm's pipeline also includes Tildacerfont and Cortibon for the treatment of Major Depressive Disorder, SPR202 for the treatment of Congenital Adrenal Hyperplasia and SPR204 for the treatment of Post-Bariatric Hypoglycemia.

Company Info

SPRUCE BIOSCIENCES INC

611 Gateway Boulevard, Suite 740

South San Francisco CALIFORNIA 94104 US

CEO: Richard King

Employees: 9

SPRB Company Website

SPRB Investor Relations

Phone: 14156554168

SPRUCE BIOSCIENCES INC / SPRB FAQ

Can you describe the business of SPRUCE BIOSCIENCES INC?

Spruce Biosciences, Inc. is a biopharmaceutical company, which engages in developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need. The company is headquartered in South San Francisco, California and currently employs 9 full-time employees. The company went IPO on 2020-10-09. The firm has acquired an exclusive worldwide license agreement for tralesinidase alfa enzyme replacement therapy (TA-ERT) for the treatment of Sanfilippo Syndrome Type B (MPS IIIB). The TA-ERT is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) with modified human insulin-like growth factor 2 via an amino acid linker. TA-ERT is intended as an enzyme replacement therapy for the treatment of patients with MPS IIIB who lack rhNAGLU enzyme activity. The firm's pipeline also includes Tildacerfont and Cortibon for the treatment of Major Depressive Disorder, SPR202 for the treatment of Congenital Adrenal Hyperplasia and SPR204 for the treatment of Post-Bariatric Hypoglycemia.


Can you provide the latest stock price for SPRUCE BIOSCIENCES INC?

The current stock price of SPRB is 79.99 USD. The price increased by 8.53% in the last trading session.


Does SPRB stock pay dividends?

SPRB does not pay a dividend.


What is the ChartMill technical and fundamental rating of SPRB stock?

SPRB has a ChartMill Technical rating of 4 out of 10 and a ChartMill Fundamental rating of 1 out of 10.


How is the valuation of SPRUCE BIOSCIENCES INC (SPRB) based on its PE ratio?

SPRUCE BIOSCIENCES INC (SPRB) does not have a PE ratio as the earnings reported over the last twelve months were negative (-84.83).


Is SPRUCE BIOSCIENCES INC (SPRB) stock a good buy?

This depends on your investment goals. Check the Technical and Fundamental Analysis tabs for insights on SPRB.


What is the next earnings date for SPRB stock?

SPRUCE BIOSCIENCES INC (SPRB) will report earnings on 2026-04-13, after the market close.


SPRB Technical Analysis

ChartMill assigns a technical rating of 4 / 10 to SPRB. When comparing the yearly performance of all stocks, SPRB is one of the better performing stocks in the market, outperforming 99.99% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

SPRB Fundamental Analysis

ChartMill assigns a fundamental rating of 1 / 10 to SPRB. While SPRB seems to be doing ok healthwise, there are quite some concerns on its profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

SPRB Financial Highlights

Over the last trailing twelve months SPRB reported a non-GAAP Earnings per Share(EPS) of -84.83. The EPS decreased by -19.06% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -312.67%
ROE -888.95%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%7.43%
Sales Q2Q%-100%
EPS 1Y (TTM)-19.06%
Revenue 1Y (TTM)-90.18%

SPRB Forecast & Estimates

8 analysts have analysed SPRB and the average price target is 213.69 USD. This implies a price increase of 167.15% is expected in the next year compared to the current price of 79.99.

For the next year, analysts expect an EPS growth of 85.84% and a revenue growth -100% for SPRB


Analysts
Analysts80
Price Target213.69 (167.15%)
EPS Next Y85.84%
Revenue Next Year-100%

SPRB Ownership

Ownership
Inst Owners41.05%
Ins Owners8.68%
Short Float %8.99%
Short Ratio0.63