Logo image of SPRB

SPRUCE BIOSCIENCES INC (SPRB) Stock Overview

USA - NASDAQ:SPRB - US85209E2081 - Common Stock

157.82 USD
+1.21 (+0.77%)
Last: 10/17/2025, 8:00:02 PM

SPRB Key Statistics, Chart & Performance

Key Statistics
Market Cap88.38M
Revenue(TTM)1.30M
Net Income(TTM)-48338000
Shares560.00K
Float550.00K
52 Week High240
52 Week Low0.08
Yearly DividendN/A
Dividend YieldN/A
EPS(TTM)-86
PEN/A
Fwd PEN/A
Earnings (Next)11-10 2025-11-10/amc
IPO2020-10-09
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology


SPRB short term performance overview.The bars show the price performance of SPRB in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 0 10K 20K 30K 40K

SPRB long term performance overview.The bars show the price performance of SPRB in the last 1, 2 and 3 years. 1 year 2 years 3 years 5K 10K 15K 20K

The current stock price of SPRB is 157.82 USD. In the past month the price increased by 1784.42%. In the past year, price increased by 21195.4%.

SPRUCE BIOSCIENCES INC / SPRB Daily stock chart

SPRB Latest News, Press Relases and Analysis

SPRB Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
Full List
Symbol
Company Name
TA
FA
PE
Market Cap
ABBV ABBVIE INC 21.68 405.55B
AMGN AMGEN INC 13.7 160.87B
GILD GILEAD SCIENCES INC 15.87 152.38B
VRTX VERTEX PHARMACEUTICALS INC 24.61 106.87B
ALNY ALNYLAM PHARMACEUTICALS INC N/A 63.14B
REGN REGENERON PHARMACEUTICALS 12.67 61.27B
ARGX ARGENX SE - ADR 91.6 51.94B
INSM INSMED INC N/A 35.04B
ONC BEONE MEDICINES LTD-ADR 5.11 34.76B
BNTX BIONTECH SE-ADR N/A 25.28B
NTRA NATERA INC N/A 24.94B
BIIB BIOGEN INC 8.93 20.97B

About SPRB

Company Profile

SPRB logo image Spruce Biosciences, Inc. is a biopharmaceutical company, which engages in developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need. The company is headquartered in South San Francisco, California and currently employs 9 full-time employees. The company went IPO on 2020-10-09. The firm has acquired an exclusive worldwide license agreement for tralesinidase alfa enzyme replacement therapy (TA-ERT) for the treatment of Sanfilippo Syndrome Type B (MPS IIIB). The TA-ERT is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) with modified human insulin-like growth factor 2 via an amino acid linker. TA-ERT is intended as an enzyme replacement therapy for the treatment of patients with MPS IIIB who lack rhNAGLU enzyme activity. The firm's pipeline also includes Tildacerfont and Cortibon for the treatment of Major Depressive Disorder, SPR202 for the treatment of Congenital Adrenal Hyperplasia and SPR204 for the treatment of Post-Bariatric Hypoglycemia.

Company Info

SPRUCE BIOSCIENCES INC

611 Gateway Boulevard, Suite 740

South San Francisco CALIFORNIA 94104 US

CEO: Richard King

Employees: 9

SPRB Company Website

SPRB Investor Relations

Phone: 14156554168

SPRUCE BIOSCIENCES INC / SPRB FAQ

What is the stock price of SPRUCE BIOSCIENCES INC today?

The current stock price of SPRB is 157.82 USD. The price increased by 0.77% in the last trading session.


What is the ticker symbol for SPRUCE BIOSCIENCES INC stock?

The exchange symbol of SPRUCE BIOSCIENCES INC is SPRB and it is listed on the Nasdaq exchange.


On which exchange is SPRB stock listed?

SPRB stock is listed on the Nasdaq exchange.


What is the price forecast or stock price prediction for SPRUCE BIOSCIENCES INC stock?

6 analysts have analysed SPRB and the average price target is 10.2 USD. This implies a price decrease of -93.54% is expected in the next year compared to the current price of 157.82. Check the SPRUCE BIOSCIENCES INC stock analysts ratings, price target forecast and up-and down grades for more detailed information.


What is SPRUCE BIOSCIENCES INC worth?

SPRUCE BIOSCIENCES INC (SPRB) has a market capitalization of 88.38M USD. This makes SPRB a Micro Cap stock.


How many employees does SPRUCE BIOSCIENCES INC have?

SPRUCE BIOSCIENCES INC (SPRB) currently has 9 employees.


What are the support and resistance levels for SPRUCE BIOSCIENCES INC (SPRB) stock?

SPRUCE BIOSCIENCES INC (SPRB) has a support level at 157.81 and a resistance level at 176.92. Check the full technical report for a detailed analysis of SPRB support and resistance levels.


Is SPRUCE BIOSCIENCES INC (SPRB) expected to grow?

The Revenue of SPRUCE BIOSCIENCES INC (SPRB) is expected to decline by -80.37% in the next year. Check the estimates tab for more information on the SPRB EPS, Sales, EBIT and EBITDA future analyst estimates.


Should I buy SPRUCE BIOSCIENCES INC (SPRB) stock?

There is no straightforward answer here. It depends on your investment strategy as different types of investors will look at different aspects. In any case it is important to make an informed decision and these pages can help you forming an opinion:


Does SPRUCE BIOSCIENCES INC (SPRB) stock pay dividends?

SPRB does not pay a dividend.


When does SPRUCE BIOSCIENCES INC (SPRB) report earnings?

SPRUCE BIOSCIENCES INC (SPRB) will report earnings on 2025-11-10, after the market close.


What is the Price/Earnings (PE) ratio of SPRUCE BIOSCIENCES INC (SPRB)?

SPRUCE BIOSCIENCES INC (SPRB) does not have a PE ratio as the earnings reported over the last twelve months were negative (-86).


What is the Short Interest ratio of SPRUCE BIOSCIENCES INC (SPRB) stock?

The outstanding short interest for SPRUCE BIOSCIENCES INC (SPRB) is 0.11% of its float. Check the ownership tab for more information on the SPRB short interest.


SPRB Technical Analysis

ChartMill assigns a technical rating of 9 / 10 to SPRB. When comparing the yearly performance of all stocks, SPRB is one of the better performing stocks in the market, outperforming 100% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

SPRB Fundamental Analysis

ChartMill assigns a fundamental rating of 2 / 10 to SPRB. While SPRB seems to be doing ok healthwise, there are quite some concerns on its profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

SPRB Financial Highlights

Over the last trailing twelve months SPRB reported a non-GAAP Earnings per Share(EPS) of -86. The EPS decreased by -396.54% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -221.53%
ROE -366.75%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%78.79%
Sales Q2Q%-100%
EPS 1Y (TTM)-396.54%
Revenue 1Y (TTM)-86.42%

SPRB Forecast & Estimates

6 analysts have analysed SPRB and the average price target is 10.2 USD. This implies a price decrease of -93.54% is expected in the next year compared to the current price of 157.82.

For the next year, analysts expect an EPS growth of 13.62% and a revenue growth -80.37% for SPRB


Analysts
Analysts43.33
Price Target10.2 (-93.54%)
EPS Next Y13.62%
Revenue Next Year-80.37%

SPRB Ownership

Ownership
Inst Owners21.05%
Ins Owners2.32%
Short Float %0.11%
Short Ratio0