Logo image of SION

SIONNA THERAPEUTICS INC (SION) Stock Price, Forecast & Analysis

USA - Nasdaq - NASDAQ:SION - US8294011080 - Common Stock

39.25 USD
+2.65 (+7.24%)
Last: 1/9/2026, 8:26:38 PM
39.59 USD
+0.34 (+0.87%)
After Hours: 1/9/2026, 8:26:38 PM

SION Key Statistics, Chart & Performance

Key Statistics
Market Cap1.75B
Revenue(TTM)N/A
Net Income(TTM)-70.68M
Shares44.63M
Float29.91M
52 Week HighN/A
52 Week LowN/A
Yearly DividendN/A
Dividend Yield0%
EPS(TTM)-4.87
PEN/A
Fwd PEN/A
Earnings (Next)03-16 2026-03-16
IPO2025-02-07
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology


SION short term performance overview.The bars show the price performance of SION in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 0 20 40 60 80

SION long term performance overview.The bars show the price performance of SION in the last 1, 2 and 3 years. 1 year 2 years 3 years

The current stock price of SION is 39.25 USD. In the past month the price decreased by -4.76%.

SIONNA THERAPEUTICS INC / SION Daily stock chart

SION Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
Full List
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Company Name
TA
FA
PE
Market Cap
ABBV ABBVIE INC 23.29 388.96B
AMGN AMGEN INC 14.91 175.60B
GILD GILEAD SCIENCES INC 14.79 150.25B
VRTX VERTEX PHARMACEUTICALS INC 26.72 117.69B
REGN REGENERON PHARMACEUTICALS 17.7 83.72B
ALNY ALNYLAM PHARMACEUTICALS INC 780.96 52.62B
INSM INSMED INC N/A 37.53B
NTRA NATERA INC N/A 32.34B
BIIB BIOGEN INC 11.21 27.52B
RVMD REVOLUTION MEDICINES INC N/A 22.94B
INCY INCYTE CORP 16.65 20.98B
UTHR UNITED THERAPEUTICS CORP 18.31 20.81B

About SION

Company Profile

SION logo image Sionna Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company. The company is headquartered in Waltham, Massachusetts and currently employs 41 full-time employees. The company went IPO on 2025-02-07. The firm is focused on researching and developing novel medicines for cystic fibrosis. The company is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). The company is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. The company is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.

Company Info

SIONNA THERAPEUTICS INC

21 Hickory Drive, Suite 500

Waltham MASSACHUSETTS US

Employees: 41

SION Company Website

Phone: 16178192020

SIONNA THERAPEUTICS INC / SION FAQ

What does SION do?

Sionna Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company. The company is headquartered in Waltham, Massachusetts and currently employs 41 full-time employees. The company went IPO on 2025-02-07. The firm is focused on researching and developing novel medicines for cystic fibrosis. The company is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). The company is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. The company is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.


What is the current price of SION stock?

The current stock price of SION is 39.25 USD. The price increased by 7.24% in the last trading session.


What is the dividend status of SIONNA THERAPEUTICS INC?

SION does not pay a dividend.


How is the ChartMill rating for SIONNA THERAPEUTICS INC?

SION has a ChartMill Technical rating of 3 out of 10 and a ChartMill Fundamental rating of 3 out of 10.


Where is SIONNA THERAPEUTICS INC (SION) stock traded?

SION stock is listed on the Nasdaq exchange.


Can you provide the ownership details for SION stock?

You can find the ownership structure of SIONNA THERAPEUTICS INC (SION) on the Ownership tab.


SION Technical Analysis

ChartMill assigns a technical rating of 3 / 10 to SION.


Chartmill TA Rating
Chartmill Setup Rating

SION Fundamental Analysis

ChartMill assigns a fundamental rating of 3 / 10 to SION. SION has a great financial health rating, but its profitability evaluates not so good.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

SION Financial Highlights

Over the last trailing twelve months SION reported a non-GAAP Earnings per Share(EPS) of -4.87. The EPS decreased by -30.53% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -20.83%
ROE -21.97%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%57.5%
Sales Q2Q%N/A
EPS 1Y (TTM)-30.53%
Revenue 1Y (TTM)N/A

SION Forecast & Estimates

14 analysts have analysed SION and the average price target is 43.42 USD. This implies a price increase of 10.63% is expected in the next year compared to the current price of 39.25.


Analysts
Analysts84.29
Price Target43.42 (10.62%)
EPS Next Y6.09%
Revenue Next YearN/A

SION Ownership

Ownership
Inst Owners67.43%
Ins Owners1.38%
Short Float %9.62%
Short Ratio9.44