SIONNA THERAPEUTICS INC (SION) Stock Price & Overview

NASDAQ:SION • US8294011080

38.775 USD
+1.24 (+3.32%)
Last: Mar 10, 2026, 01:28 PM

The current stock price of SION is 38.775 USD. Today SION is up by 3.32%. In the past month the price increased by 3.93%. In the past year, price increased by 150.53%.

SION Key Statistics

52-Week Range7.255 - 45
Current SION stock price positioned within its 52-week range.
1-Month Range32.565 - 39.865
Current SION stock price positioned within its 1-month range.
Market Cap
1.731B
P/E
N/A
Fwd P/E
N/A
EPS (TTM)
-4.87
Dividend Yield
N/A

SION Stock Performance

Today
+3.32%
1 Week
+10.64%
1 Month
+3.93%
3 Months
-12.25%
Longer-term
6 Months +64.39%
1 Year +150.53%
2 Years N/A
3 Years N/A
5 Years N/A
10 Years N/A

SION Stock Chart

SIONNA THERAPEUTICS INC / SION Daily stock chart

SION Technical Analysis

ChartMill assigns a technical rating of 6 / 10 to SION. When comparing the yearly performance of all stocks, SION is one of the better performing stocks in the market, outperforming 94.65% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating
SION Full Technical Analysis Report

SION Fundamental Analysis

ChartMill assigns a fundamental rating of 3 / 10 to SION. SION has a great financial health rating, but its profitability evaluates not so good.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend
SION Full Fundamental Analysis Report

SION Earnings

Next Earnings DateMar 16, 2026
Last Earnings DateNov 5, 2025
PeriodQ3 / 2025
EPS Reported-$0.46
Revenue Reported
EPS Surprise 6.88%
Revenue Surprise %
SION Earnings History

SION Forecast & Estimates

16 analysts have analysed SION and the average price target is 45.75 USD. This implies a price increase of 18% is expected in the next year compared to the current price of 38.775.


Analysts
Analysts83.75
Price Target45.75 (17.99%)
EPS Next Y6.34%
Revenue Next YearN/A
SION Forecast & Estimates

SION Groups

Sector & Classification

SION Financial Highlights

Over the last trailing twelve months SION reported a non-GAAP Earnings per Share(EPS) of -4.87. The EPS decreased by -30.53% compared to the year before.


Income Statements
Revenue(TTM)N/A
Net Income(TTM)-70.68M
Industry RankSector Rank
PM (TTM) N/A
ROA -20.83%
ROE -21.97%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%57.5%
Sales Q2Q%N/A
EPS 1Y (TTM)-30.53%
Revenue 1Y (TTM)N/A
SION financials

SION Ownership

Ownership
Inst Owners73.4%
Shares44.63M
Float30.33M
Ins Owners1.38%
Short Float %10.14%
Short Ratio9.97
SION Ownership

SION Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
Full List
SymbolCompany NameTechnical RatingFundamental RatingFPEMarket Cap
ABBV ABBVIE INC15.37402.17B
AMGN AMGEN INC16.62203.213B
GILD GILEAD SCIENCES INC16.82182.029B
VRTX VERTEX PHARMACEUTICALS INC25.86117.075B
REGN REGENERON PHARMACEUTICALS16.6982.631B
ALNY ALNYLAM PHARMACEUTICALS INC43.3142.915B
INSM INSMED INC N/A30.852B
NTRA NATERA INC N/A29.086B
BIIB BIOGEN INC11.8427.626B
UTHR UNITED THERAPEUTICS CORP18.3123.193B
MRNA MODERNA INC N/A22.014B
EXAS EXACT SCIENCES CORP340.5519.797B
RVMD REVOLUTION MEDICINES INC N/A19.775B

About SION

Company Profile

SION logo image Sionna Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company. The company is headquartered in Waltham, Massachusetts and currently employs 41 full-time employees. The company went IPO on 2025-02-07. The firm is focused on researching and developing novel medicines for cystic fibrosis. The company is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). The company is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. The company is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.

Company Info

IPO: 2025-02-07

SIONNA THERAPEUTICS INC

21 Hickory Drive, Suite 500

Waltham MASSACHUSETTS US

Employees: 41

SION Company Website

Phone: 16178192020

SIONNA THERAPEUTICS INC / SION FAQ

What does SION do?

Sionna Therapeutics, Inc. operates as a clinical-stage biopharmaceutical company. The company is headquartered in Waltham, Massachusetts and currently employs 41 full-time employees. The company went IPO on 2025-02-07. The firm is focused on researching and developing novel medicines for cystic fibrosis. The company is advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in nucleotide-binding domain 1 (NBD1). The company is conducting ongoing Phase I trials of its two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (PK) profile of single and multiple ascending doses in healthy subjects. The company is also developing a portfolio of cystic fibrosis transmembrane conductance regulator (CFTR) modulators designed to work synergistically with its NBD1 stabilizers to improve CFTR function. Its portfolio also includes Galicaftor (SION-2222) and SION-2851, which are TMD1-directed CFTR correctors; SION-109, an ICL4-directed CFTR corrector, and Navocaftor (SION-3067), is a clinical-stage potentiator of CFTR gating activity.


What is the current price of SION stock?

The current stock price of SION is 38.775 USD. The price increased by 3.32% in the last trading session.


What is the dividend status of SIONNA THERAPEUTICS INC?

SION does not pay a dividend.


How is the ChartMill rating for SIONNA THERAPEUTICS INC?

SION has a ChartMill Technical rating of 6 out of 10 and a ChartMill Fundamental rating of 3 out of 10.


Where is SIONNA THERAPEUTICS INC (SION) stock traded?

SION stock is listed on the Nasdaq exchange.


Can you provide the ownership details for SION stock?

You can find the ownership structure of SIONNA THERAPEUTICS INC (SION) on the Ownership tab.