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GRAIL INC (NASDAQ:GRAL) Reports Mixed Q2 2025 Earnings: Revenue Misses, Loss Narrows

By Mill Chart

Last update: Aug 12, 2025

GRAIL INC (NASDAQ:GRAL) reported its second-quarter 2025 financial results, revealing mixed performance relative to analyst expectations. The company, which focuses on early cancer detection through its Galleri test, posted revenue of $35.5 million, falling short of the consensus estimate of $38.3 million. Meanwhile, its earnings per share (EPS) came in at -$3.18, slightly better than the anticipated -$3.64.

Key Financial Highlights vs. Estimates

  • Revenue Miss: Reported sales of $35.5 million fell 7.2% below expectations, signaling slower-than-expected adoption or reimbursement challenges.
  • Narrower Loss: The EPS loss of -$3.18 was less severe than projected, suggesting cost controls or operational efficiencies may be improving.
  • Galleri Test Growth: U.S. revenue from Galleri grew 21% year-over-year to $34.2 million, while tests sold increased 29% to over 45,000.

Market Reaction

Following the earnings release, GRAL shares declined 2.6% in after-hours trading. This suggests investor disappointment with the revenue miss, despite the narrower-than-expected loss. Over the past month, the stock has dropped 12.8%, reflecting broader market skepticism or concerns about the company’s path to profitability.

Upcoming Catalysts

GRAIL highlighted that detailed results from its PATHFINDER 2 study—enrolling 25,000 participants—will be submitted for presentation at the European Society for Medical Oncology (ESMO) Congress in October 2025. This could serve as a near-term catalyst if the data reinforces the clinical utility of Galleri.

Analyst Expectations for Future Quarters

  • Q3 2025: Analysts forecast revenue of $35.3 million and an EPS loss of -$3.58.
  • Full-Year 2025: Estimated sales stand at $148.8 million, with an EPS loss of -$14.23.

While GRAIL continues to demonstrate growth in test adoption, the revenue shortfall raises questions about its ability to meet long-term sales targets. Investors will likely focus on upcoming clinical data and execution in reimbursement strategies.

For more detailed earnings estimates and historical performance, see GRAIL’s earnings estimates.

Disclaimer: This article is for informational purposes only and does not constitute investment advice.

GRAIL INC

NASDAQ:GRAL (8/12/2025, 8:00:01 PM)

After market: 33 -0.6 (-1.79%)

33.6

+0.91 (+2.78%)



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