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Exelixis Inc (NASDAQ:EXEL) Embodies the Affordable Growth Investment Strategy

By Mill Chart

Last update: Sep 13, 2025

Investors seeking growth opportunities at reasonable valuations often turn to strategies that balance expansion potential with financial prudence. The "Affordable Growth" approach specifically targets companies demonstrating strong growth trajectories, solid profitability, and healthy financials while trading at valuations that don’t fully price in future prospects. This method avoids overpaying for growth by emphasizing fundamental strength across multiple dimensions, making it particularly relevant in both bullish and cautious market environments.

EXELIXIS INC

Growth Trajectory and Momentum

EXELIXIS INC (NASDAQ:EXEL) stands out with a strong growth profile, earning a ChartMill Growth Rating of 8 out of 10. The company has demonstrated impressive historical performance with revenue growing at an average annual rate of 17.51% over recent years, while earnings per share surged 67.74% in the last year alone. Looking forward, analysts project EPS growth of 22.20% annually, indicating accelerating momentum. This combination of strong historical execution and optimistic forward estimates suggests the company is successfully scaling its oncology-focused product portfolio, including its flagship cabozantinib products.

Attractive Valuation Metrics

Despite its growth credentials, Exelixis trades at valuations that remain reasonable relative to both its industry and broader market. The stock carries a ChartMill Valuation Rating of 8, supported by several notable metrics:

  • P/E ratio of 18.82, cheaper than 94.45% of biotechnology peers
  • Forward P/E of 13.48, below the industry average and S&P 500 benchmark
  • Enterprise Value/EBITDA and Price/Free Cash Flow ratios both rank in the top 5% most attractive in its sector

These valuation indicators suggest the market may not be fully appreciating Exelixis's growth potential, creating what affordable growth investors look for, a potential valuation gap.

Profitability and Financial Health

The company's investment case is further strengthened by exceptional profitability and financial health scores. Exelixis achieves a Profitability Rating of 8, driven by:

  • Return on Equity of 29.62% (top 3% of industry)
  • Operating margin of 33.71% (top 2% of industry)
  • Gross margin exceeding 96%

Equally important, the company maintains a near-perfect Health Rating of 9, featuring:

  • Zero debt on its balance sheet
  • Altman-Z score of 11.81 indicating very low bankruptcy risk
  • Strong liquidity with current and quick ratios both above 3.4

These factors provide a margin of safety that growth investors prioritize, ensuring the company can weather economic uncertainty while funding its expansion.

Strategic Position in Oncology Market

Exelixis's fundamental strength derives from its strategic focus on developing and commercializing treatments for difficult-to-treat cancers. With four marketed products and a promising pipeline including zanzalintinib, the company has established a sustainable franchise in the growing oncology market. The combination of patented products, high margins, and continued innovation creates a durable competitive advantage that supports both current profitability and future growth potential.

For investors interested in exploring similar affordable growth opportunities, additional screening results are available through our Affordable Growth Stock Screener.

Disclaimer: This analysis is based on fundamental data and ratings provided by ChartMill and should not be considered investment advice. Investors should conduct their own research and consider their individual financial circumstances before making investment decisions. Past performance does not guarantee future results.

EXELIXIS INC

NASDAQ:EXEL (10/3/2025, 3:14:51 PM)

40.33

-1.02 (-2.47%)



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