Logo image of SPRO

SPERO THERAPEUTICS INC (SPRO) Stock Overview

USA - NASDAQ:SPRO - US84833T1034 - Common Stock

2.21 USD
+0.01 (+0.45%)
Last: 10/24/2025, 8:00:02 PM
2.19 USD
-0.02 (-0.9%)
After Hours: 10/24/2025, 8:00:02 PM

SPRO Key Statistics, Chart & Performance

Key Statistics
Market Cap124.38M
Revenue(TTM)48.58M
Net Income(TTM)-53601000
Shares56.28M
Float42.53M
52 Week High3.22
52 Week Low0.51
Yearly DividendN/A
Dividend YieldN/A
EPS(TTM)-0.98
PEN/A
Fwd PE3.16
Earnings (Next)11-12 2025-11-12/amc
IPO2017-11-02
Sector
GICS SectorHealth Care
GICS IndustryBiotechnology
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS SubIndustryBiotechnology


SPRO short term performance overview.The bars show the price performance of SPRO in the last week, last 2 weeks, last month, last 3 and 6 months. 1 week 2 week 1 month 3 months 6 months 0 50 100 150 200

SPRO long term performance overview.The bars show the price performance of SPRO in the last 1, 2 and 3 years. 1 year 2 years 3 years 20 40 60 80 100

The current stock price of SPRO is 2.21 USD. In the past month the price increased by 16.93%. In the past year, price increased by 66.17%.

SPERO THERAPEUTICS INC / SPRO Daily stock chart

SPRO Latest News, Press Relases and Analysis

SPRO Competitors/Peers

The largest stocks on the US markets in the "Biotechnology" sub-industry
Full List
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TA
FA
PE
Market Cap
ABBV ABBVIE INC 21.53 402.76B
AMGN AMGEN INC 13.38 157.07B
GILD GILEAD SCIENCES INC 15.63 150.06B
VRTX VERTEX PHARMACEUTICALS INC 24.88 108.04B
REGN REGENERON PHARMACEUTICALS 12.66 61.26B
ALNY ALNYLAM PHARMACEUTICALS INC N/A 60.75B
ARGX ARGENX SE - ADR 88.74 50.32B
ONC BEONE MEDICINES LTD-ADR 5.02 34.14B
INSM INSMED INC N/A 33.75B
NTRA NATERA INC N/A 26.42B
BNTX BIONTECH SE-ADR N/A 25.40B
BIIB BIOGEN INC 9.36 21.98B

About SPRO

Company Profile

SPRO logo image Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which focuses on identifying, developing, and commercializing treatments involving bacterial infections, including multi-drug resistant bacterial infections, and rare diseases Its pipeline product candidates include Tebipenem HBr, SPR720, and SPR206. The company is headquartered in Cambridge, Massachusetts and currently employs 32 full-time employees. The company went IPO on 2017-11-02. The firm is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.

Company Info

SPERO THERAPEUTICS INC

675 Massachusetts Ave Ste 14

Cambridge MASSACHUSETTS 02139 US

CEO: Ankit Mahadevia

Employees: 32

SPRO Company Website

SPRO Investor Relations

Phone: 18572421600

SPERO THERAPEUTICS INC / SPRO FAQ

What does SPERO THERAPEUTICS INC do?

Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which focuses on identifying, developing, and commercializing treatments involving bacterial infections, including multi-drug resistant bacterial infections, and rare diseases Its pipeline product candidates include Tebipenem HBr, SPR720, and SPR206. The company is headquartered in Cambridge, Massachusetts and currently employs 32 full-time employees. The company went IPO on 2017-11-02. The firm is focused on identifying and developing novel treatments for rare diseases and diseases caused by multi-drug resistant (MDR) bacterial infections with unmet need. Its product candidate SPR720 is an investigational, chemically stable phosphate ester prodrug that is converted in vivo to SPR719 for the treatment of nontuberculous mycobacterial (NTM) pulmonary disease. Its clinical stage product candidate, tebipenem HBr is an investigational oral carbapenem antibiotic being developed for the treatment of complicated urinary tract infections (cUTIs) including acute pyelonephritis (AP) to help patients potentially reduce duration of in-patient therapy.


What is the stock price of SPERO THERAPEUTICS INC today?

The current stock price of SPRO is 2.21 USD. The price increased by 0.45% in the last trading session.


Does SPRO stock pay dividends?

SPRO does not pay a dividend.


What is the ChartMill technical and fundamental rating of SPRO stock?

SPRO has a ChartMill Technical rating of 8 out of 10 and a ChartMill Fundamental rating of 3 out of 10.


Can you provide the sector and industry classification for SPERO THERAPEUTICS INC?

SPERO THERAPEUTICS INC (SPRO) operates in the Health Care sector and the Biotechnology industry.


What is SPERO THERAPEUTICS INC worth?

SPERO THERAPEUTICS INC (SPRO) has a market capitalization of 124.38M USD. This makes SPRO a Micro Cap stock.


When does SPERO THERAPEUTICS INC (SPRO) report earnings?

SPERO THERAPEUTICS INC (SPRO) will report earnings on 2025-11-12, after the market close.


SPRO Technical Analysis

ChartMill assigns a technical rating of 8 / 10 to SPRO. When comparing the yearly performance of all stocks, SPRO is one of the better performing stocks in the market, outperforming 86.41% of all stocks.


Chartmill TA Rating
Chartmill Setup Rating

SPRO Fundamental Analysis

ChartMill assigns a fundamental rating of 3 / 10 to SPRO. The financial health of SPRO is average, but there are quite some concerns on its profitability.


Chartmill FA Analysis
Valuation
Growth
Profitability
Health
Dividend

SPRO Financial Highlights

Over the last trailing twelve months SPRO reported a non-GAAP Earnings per Share(EPS) of -0.98. The EPS decreased by -327.91% compared to the year before.


Industry RankSector Rank
PM (TTM) N/A
ROA -86.29%
ROE -163.28%
Debt/Equity 0
Chartmill High Growth Momentum
EPS Q2Q%90.91%
Sales Q2Q%39.15%
EPS 1Y (TTM)-327.91%
Revenue 1Y (TTM)-58.99%

SPRO Forecast & Estimates

7 analysts have analysed SPRO and the average price target is 5.1 USD. This implies a price increase of 130.77% is expected in the next year compared to the current price of 2.21.

For the next year, analysts expect an EPS growth of 33.34% and a revenue growth -48.42% for SPRO


Analysts
Analysts45.71
Price Target5.1 (130.77%)
EPS Next Y33.34%
Revenue Next Year-48.42%

SPRO Ownership

Ownership
Inst Owners15.56%
Ins Owners2.5%
Short Float %1.08%
Short Ratio0.88