| Feb 5, 2026 | Longitude Capital Partners V, LLC | Open Market Purchase | 1075000 | 17.00 | $ 18,275,000.00 |
| Feb 5, 2026 | Longitude 103.8 East Partners, LLC | Open Market Purchase | 1075000 | 17.00 | $ 18,275,000.00 |
| Feb 5, 2026 | Longitude 103.8 East, L.P. | Open Market Purchase | 1075000 | 17.00 | $ 18,275,000.00 |
| Feb 5, 2026 | Longitude Venture Partners V, L.P. | Open Market Purchase | 1075000 | 17.00 | $ 18,275,000.00 |
| Feb 5, 2026 | ENRIGHT PATRICK G | Other Aquisition | 3578873 | | $ 0.00 |
| Feb 5, 2026 | ENRIGHT PATRICK G | Open Market Purchase | 1075000 | 17.00 | $ 18,275,000.00 |
| Feb 5, 2026 | Durso Timothy August | Other Aquisition | 1473 | | $ 0.00 |
| Feb 5, 2026 | Waldman Reid Alexander | Other Aquisition | 1437 | | $ 0.00 |
| Feb 5, 2026 | Grant-Kels Jane M. | Other Aquisition | 2455 | | $ 0.00 |
| Feb 5, 2026 | Coric Vlad | Other Aquisition | 638262 | | $ 0.00 |
| Feb 5, 2026 | Coric Vlad | Open Market Purchase | 117646 | 17.00 | $ 1,999,982.00 |
| Feb 5, 2026 | CHILDS JOHN W | Other Aquisition | 1907889 | | $ 0.00 |
| Feb 5, 2026 | CHILDS JOHN W | Open Market Purchase | 294117 | 17.00 | $ 4,999,989.00 |
| Feb 5, 2026 | Longitude Capital Partners V, LLC | Other Aquisition | 3578873 | | $ 0.00 |
| Feb 5, 2026 | Longitude 103.8 East Partners, LLC | Other Aquisition | 3578873 | | $ 0.00 |
| Feb 5, 2026 | Longitude 103.8 East, L.P. | Other Aquisition | 3578873 | | $ 0.00 |
| Feb 5, 2026 | Longitude Venture Partners V, L.P. | Other Aquisition | 3578873 | | $ 0.00 |
| Feb 4, 2026 | SUVRETTA CAPITAL MANAGEMENT, LLC | Open Market Purchase | 282674 | 37.30 | $ 10,542,477.61 |
| Feb 4, 2026 | Cowen Aaron | Open Market Purchase | 282674 | 37.30 | $ 10,542,477.61 |
| Feb 4, 2026 | Averill Master Fund, Ltd. | Open Market Purchase | 282674 | 37.30 | $ 10,542,477.61 |
| Feb 4, 2026 | Averill Madison Master Fund, Ltd. | Open Market Purchase | 282674 | 37.30 | $ 10,542,477.61 |