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Wednesday's pre-market session: top gainers and losers

By Mill Chart

Last update: May 14, 2025

The US market session of Wednesday has yet to be opened, let's have a look at the top gainers and losers in the pre-market session today.

Gainers

TickerChangeComment
IXHL144.0%During Wednesday's pre-market session, INCANNEX HEALTHCARE INC (NASDAQ:IXHL) experienced a 144.0% increase, with the stock price reaching $0.21. The stock is trading 86.88% lower than a month ago.
SEPN70.13%Investors witnessed a remarkable surge in SEPTERNA INC (NASDAQ:SEPN) during Wednesday's pre-market session, with the stock price rising 70.13% to $11.45. Shareholders saw the stock price going 48.07% lower in the past 3 months.
LUCY60.61%During Wednesday's pre-market trading, INNOVATIVE EYEWEAR INC (NASDAQ:LUCY) demonstrated strong momentum, with the stock price rising 60.61% to $3.18. Shareholders saw the stock price going 59.92% lower in the past 3 months.
QNRX57.23%During Wednesday's pre-market session, QUOIN PHARMACEUTICALS LT-ADR (NASDAQ:QNRX) experienced a 57.23% increase, with the stock price reaching $10.0. In the last month the stock gained 20.46%.
DEVS33.81%DEVVSTREAM CORP's (NASDAQ:DEVS) shares rose 33.81% to $0.76 during Wednesday's pre-market session. Yesterday's -56.49% decline in DEVS has given way to a potential bounce-back as observed in today's pre-market session.
HWH31.4%The pre-market session on Wednesday saw a significant rise in HWH INTERNATIONAL INC's (NASDAQ:HWH) shares, climbing 31.4% to $1.59. The stock is trading 25.1% lower than 3 months ago.
NUTX24.7%During Wednesday's pre-market session, NUTEX HEALTH INC (NASDAQ:NUTX) exhibited strong growth, with the stock price climbing 24.7% to $157.04. The stock is trading 90.63% higher than 3 months ago.
ALUR23.72%ALLURION TECHNOLOGIES INC (NYSE:ALUR) experienced an impressive 23.72% increase in share price, reaching $2.92 during the pre-market session on Wednesday. A press release (Allurion Reports First Quarter 2025 Financial Results and Provides Business Update) was released earlier today.
WBUY18.9%WEBUY GLOBAL LTD-CL A's (NASDAQ:WBUY) shares rose 18.9% to $8.62. Yesterday's -18.08% decline in WBUY has given way to a potential bounce-back as observed in today's pre-market session.
SMCI18.75%The pre-market session on Wednesday saw a significant rise in SUPER MICRO COMPUTER INC's (NASDAQ:SMCI) shares, climbing 18.75% to $46.18. Continuing its strong performance from the previous session, SMCI experienced a significant 16.02% gain, setting a positive tone for today's pre-market session.

To see the full list of premarket gainers you can use our premarket gainers page.

Today's pre-market losers

TickerChangeComment
PLRZ-47.37%The pre-market session on Wednesday witnessed a 47.37% decrease in POLYRIZON LTD's (NASDAQ:PLRZ) shares, with the stock price falling to $0.01. The negative momentum from yesterday's -91.86% drop spilled over into today's pre-market session, with PLRZ recording an additional decline of 47.37%. Yesterday the company had a press release: Polyrizon Targets $3.15B Epilepsy Market with Preclinical Studies for Innovative Rescue Treatment.
AXDX-30.34%ACCELERATE DIAGNOSTICS INC's (NASDAQ:AXDX) stock price is declining with 30.34% to a price of $0.06. The negative momentum continues as AXDX experienced a -34.38% decline during the regular session yesterday, indicating ongoing challenges.
XHLD-28.23%The stock price of TEN HOLDINGS INC (NASDAQ:XHLD) is declining by 28.23%, reaching $0.99 during Wednesday's pre-market session. After a strong performance yesterday with a 112.0% gain, XHLD shows signs of retracement with a 28.23% decline in today's pre-market session.
JZXN-25.72%JIUZI HOLDINGS INC's (NASDAQ:JZXN) stock price is declining with 25.72% to a price of $2.31. The current market conditions exhibit high volatility as JZXN retraces its steps after yesterday's 13.09% gain.
HYFM-24.47%HYDROFARM HOLDINGS GROUP INC's (NASDAQ:HYFM) shares fell 24.47% to $2.5 during Wednesday's pre-market session. The negative sentiment prevails for HYFM as it recorded a -13.12% decline during the regular session yesterday, followed by another decline of 24.47% in today's pre-market session.
AFMD-22.16%AFFIMED NV's (NASDAQ:AFMD) stock price is declining with 22.16% to a price of $0.1. Yesterday's -80.66% drop during the regular session suggests that AFMD is still facing difficulties, and this sentiment extends to today's pre-market session. A press release (Affimed Announces Receipt of Nasdaq Delisting Notice) was released earlier today.
XTKG-21.33%Despite yesterday's decline, X3 HOLDINGS CO LTD (NASDAQ:XTKG) experienced a further 21.33% decrease in share price during Wednesday's pre-market session, reaching $1.66. After yesterdays gain of 91.82%, it goes down with 21.33% in today's pre-market session.
AUR-21.04%Today's pre-market session reveals a 21.04% decline in the stock price of AURORA INNOVATION INC (NASDAQ:AUR), now priced at $5.78. In the last month the share price increased with 21.39%.
MOGO-18.95%MOGO INC's (NASDAQ:MOGO) stock price is declining with 18.95% to a price of $1.24. Following yesterday's notable 53.52% increase, MOGO undergoes a 18.95% decrease in today's pre-market session, suggesting a temporary pullback. Yesterday the company had a press release: Mogo Portfolio Company WonderFi Announces Definitive Agreement to be Acquired by Robinhood Markets.
ABP-16.83%ABPRO HOLDINGS INC's (NASDAQ:ABP) stock price decreased by 16.83% to $0.17. In the last month the share price dropped with 30.51%.

Our premarket losers page will show you the full list.

SUPER MICRO COMPUTER INC

NASDAQ:SMCI (11/21/2025, 8:00:28 PM)

After market: 32.4106 +0.22 (+0.69%)

32.19

+0.63 (+2%)


ACCELERATE DIAGNOSTICS INC

NASDAQ:AXDX (5/14/2025, 8:20:36 PM)

After market: 0.052 +0.02 (+52.94%)

0.034

-0.05 (-61.36%)


AFFIMED NV

NASDAQ:AFMD (5/19/2025, 8:00:00 PM)

After market: 0.1731 -0.01 (-4.63%)

0.1815

-0.1 (-34.95%)


MOGO INC

NASDAQ:MOGO (11/21/2025, 8:00:01 PM)

After market: 1.14 -0.02 (-1.72%)

1.16

+0.05 (+4.5%)


ABPRO HOLDINGS INC

NASDAQ:ABP (11/21/2025, 8:10:44 PM)

After market: 7.04 0 (0%)

7.04

+0.67 (+10.52%)


HYDROFARM HOLDINGS GROUP INC

NASDAQ:HYFM (11/21/2025, 8:00:02 PM)

1.55

-0.06 (-3.73%)


JIUZI HOLDINGS INC

NASDAQ:JZXN (11/21/2025, 8:00:02 PM)

After market: 0.1811 -0.01 (-5.48%)

0.1916

+0 (+0.79%)


QUOIN PHARMACEUTICALS LT-ADR

NASDAQ:QNRX (11/21/2025, 8:00:01 PM)

After market: 17.93 -0.37 (-2%)

18.295

-0.12 (-0.68%)


AURORA INNOVATION INC

NASDAQ:AUR (11/21/2025, 8:12:51 PM)

After market: 3.77 -0.01 (-0.26%)

3.78

+0.01 (+0.27%)


INCANNEX HEALTHCARE INC

NASDAQ:IXHL (11/21/2025, 8:00:02 PM)

After market: 0.3146 +0 (+0.03%)

0.3145

-0.02 (-5.24%)


NUTEX HEALTH INC

NASDAQ:NUTX (11/21/2025, 8:00:02 PM)

After market: 136.92 0 (0%)

136.92

-5.42 (-3.81%)


INNOVATIVE EYEWEAR INC

NASDAQ:LUCY (11/21/2025, 8:00:01 PM)

After market: 1.54 -0.02 (-1.28%)

1.56

+0.01 (+0.65%)


ALLURION TECHNOLOGIES INC

NYSE:ALUR (11/21/2025, 8:11:49 PM)

After market: 1.2605 +0 (+0.04%)

1.26

0 (0%)


WEBUY GLOBAL LTD-CL A

NASDAQ:WBUY (11/21/2025, 8:05:25 PM)

1.3

-0.1 (-7.14%)


HWH INTERNATIONAL INC

NASDAQ:HWH (11/21/2025, 8:00:02 PM)

1.51

+0.01 (+0.67%)


X3 HOLDINGS CO LTD

NASDAQ:XTKG (11/21/2025, 8:06:29 PM)

1.84

+0.11 (+6.36%)


SEPTERNA INC

NASDAQ:SEPN (11/21/2025, 8:00:02 PM)

After market: 26.25 +0.69 (+2.7%)

25.56

+1.79 (+7.53%)


POLYRIZON LTD

NASDAQ:PLRZ (11/21/2025, 8:00:01 PM)

After market: 0.6322 0 (-0.58%)

0.6359

+0.05 (+8.7%)


DEVVSTREAM CORP

NASDAQ:DEVS (11/21/2025, 8:23:04 PM)

1.39

-0.08 (-5.44%)


TEN HOLDINGS INC

NASDAQ:XHLD (11/21/2025, 8:06:12 PM)

After market: 0.1971 -0.01 (-3.05%)

0.2033

+0.01 (+6.72%)



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