Which S&P500 stocks are moving on Wednesday?
By Mill Chart
Last update: Dec 3, 2025
Let's delve into the developments on the US markets one hour before the close of the markets on Wednesday. Below, you'll find the top gainers and losers within the S&P500 index during today's session.
Top gainers
| Ticker | Change | Comment |
|---|---|---|
| MCHP | 9.98% | MICROCHIP TECHNOLOGY INC's (NASDAQ:MCHP) shares rose 9.98% to $62.37 during Wednesday's session. |
| ON | 9.05% | ON SEMICONDUCTOR's (NASDAQ:ON) stock price is advancing with 9.05% to a price of $56.14. A press release (onsemi and Innoscience Announce Plans to Collaborate to Speed Global Rollout of GaN Power Portfolio) was released yesterday. |
| VRTX | 6.71% | In an impressive move, VERTEX PHARMACEUTICALS INC's (NASDAQ:VRTX) shares recorded a 6.71% increase, closing at $462.2 during Wednesday's session. |
| CRL | 6.24% | Investors witnessed a remarkable 6.24% rise in CHARLES RIVER LABORATORIES's (NYSE:CRL) shares, which climbed to $185.67 during Wednesday's session. In the last 6 months the share price increased with 20.77%. |
| BMY | 6.1% | BRISTOL-MYERS SQUIBB CO's (NYSE:BMY) shares rose 6.1% to $51.2 during Wednesday's session. |
| HUM | 5.99% | HUMANA INC (NYSE:HUM) experienced a significant 5.99% increase, reaching $256.46 during Wednesday's session. In the last 3 months the stock lost 21.42%. |
| ODFL | 5.78% | With a 5.78% surge, OLD DOMINION FREIGHT LINE's (NASDAQ:ODFL) stock price reached $149.63 during Wednesday's session, signaling positive momentum. Shareholders saw the stock price going 30.32% lower is the past year. |
| HOOD | 5.65% | Investors witnessed a remarkable 5.65% rise in ROBINHOOD MARKETS INC - A's (NASDAQ:HOOD) shares, which climbed to $133.07 during Wednesday's session. Shareholders saw the stock price going 24.4% higher in the past 3 months. |
| NXPI | 5.54% | NXP SEMICONDUCTORS NV's (NASDAQ:NXPI) stock price increased by 5.54% to $227.27. |
| LYV | 5.2% | LIVE NATION ENTERTAINMENT IN's (NYSE:LYV) shares rose 5.2% to $135.23. In the last 3 months the share price dropped with 21.34%. |
Our top gainers page will show you the full list.
Top losers
| Ticker | Change | Comment |
|---|---|---|
| ARE | -10.15% | ALEXANDRIA REAL ESTATE EQUIT's (NYSE:ARE) stock price decreased by 10.15% to $48.37. A press release (Glancy Prongay & Murray LLP, a Leading Securities Fraud Law Firm Encourages Alexandria Real Estate Equities, Inc. (ARE) Shareholders To Inquire About Securities Fraud Class Action) was released earlier today. |
| SNDK | -6.94% | SANDISK CORP's (NASDAQ:SNDK) shares fell 6.94% to $191.09 during Wednesday's session. In the last 3 months the share price increased with 200.0%. |
| PSKY | -6.67% | PARAMOUNT SKYDANCE CL B's (NASDAQ:PSKY) stock price faced a 6.67% decline, reaching $14.77 during Wednesday's session. |
| NFLX | -4.98% | There was a notable decline in NETFLIX INC's (NASDAQ:NFLX) shares, as they dropped 4.98% to $103.91 during Wednesday's session. |
| STX | -4.68% | Investors witnessed a 4.68% decrease in SEAGATE TECHNOLOGY HOLDINGS's (NASDAQ:STX) stock price, which closed at $254.38 during Wednesday's session. In the last 3 months the share price increased with 41.83%. |
| COR | -4.21% | During Wednesday's session, CENCORA INC's (NYSE:COR) shares took a tumble, falling 4.21% to $335.89. In the last 6 months the stock gained 21.36%. |
| DOC | -3.27% | Investors witnessed a 3.27% decrease in HEALTHPEAK PROPERTIES INC's (NYSE:DOC) stock price, which closed at $17.45 during Wednesday's session. |
| WDC | -3.16% | There was a downturn in WESTERN DIGITAL CORP's (NASDAQ:WDC) shares, as they experienced a 3.16% decline, closing at $154.93 during Wednesday's session. In the last 3 months the share price increased with 73.83%. |
| LYB | -2.93% | LYONDELLBASELL INDU-CL A's (NYSE:LYB) stock price decreased by 2.93% to $46.38. In the last year the share price dropped with 37.45%. |
| MCK | -2.92% | Investors witnessed a 2.92% decrease in MCKESSON CORP's (NYSE:MCK) stock price, which closed at $805.45 during Wednesday's session. The stock is trading 20.7% higher than 3 months ago. |
To see the full list of top losers you can use our top losers page.
53.97
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220.91
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55.86
-0.04 (-0.07%)
463.86
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276.85
-0.72 (-0.26%)
816.06
+1.43 (+0.18%)
146.07
-1.2 (-0.81%)
89.46
-1.07 (-1.18%)
173.13
+2.06 (+1.2%)
304.01
+19.54 (+6.87%)
200.46
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75.22
+1.69 (+2.3%)
377.41
+42.87 (+12.81%)
241.15
+3.26 (+1.37%)
16.71
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62.16
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335.69
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48.71
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115.27
-0.12 (-0.1%)
12.06
-0.21 (-1.71%)
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