These stocks that are showing activity before the opening bell on Wednesday.

Last update: Apr 30, 2025

Before the US market kicks off on Wednesday, let's examine the pre-market session and unveil the notable performers among the top gainers and losers.

Gainers

Ticker	Change	Comment
RGLS	133.0%	Exciting news for REGULUS THERAPEUTICS INC (NASDAQ:RGLS) as their shares soared 133.0% to $7.85 during the pre-market session on Wednesday. Earlier today the company had a press release: Shareholder Alert: The Ademi Firm Investigates Whether Regulus Therapeutics Inc. Is Obtaining a Fair Price for Its Public Shareholders.
JFBR	44.71%	During Wednesday's pre-market session, JEFFS BRANDS LTD (NASDAQ:JFBR) experienced a 44.71% increase, with the stock price reaching $1.23. The stock is trading 63.83% lower than 3 months ago.
LGMK	28.83%	During Wednesday's pre-market trading, LOGICMARK INC (NASDAQ:LGMK) demonstrated strong momentum, with the stock price rising 28.83% to $0.02. Yesterday's gain of 26.36% continues in today's pre-market with 28.83%.
STSS	27.8%	Pre-market trading on Wednesday showed positive momentum for SHARPS TECHNOLOGY INC (NASDAQ:STSS), as the stock price advanced 27.8% to reach $6.39. Despite a -11.97% decrease just yesterday, there is a notable recovery in today's pre-market session for STSS.
WW	26.12%	During Wednesday's pre-market trading, WW INTERNATIONAL INC (NASDAQ:WW) demonstrated strong momentum, with the stock price rising 26.12% to $0.92. After recording a 77.03% gain in the previous session, WW maintains its positive trajectory in today's pre-market, with an additional 26.12% increase. WW INTERNATIONAL INC is releasing earnings today.
PTPI	25.38%	During Wednesday's pre-market session, PETROS PHARMACEUTICALS INC (NASDAQ:PTPI) exhibited strong growth, with the stock price climbing 25.38% to $0.02. After experiencing a decline of -77.55% yesterday, PTPI shows signs of a rebound in today's pre-market session. A press release (Petros Proprietary Technology Platform Aligns with April 15, 2025 President Trump Executive Order Advancing Rx-to-OTC Reclassification Reforms) was released yesterday.
NVNI	20.19%	Pre-market trading on Wednesday showed positive momentum for NVNI GROUP LTD (NASDAQ:NVNI), as the stock price advanced 20.19% to reach $0.26. The positive trend witnessed yesterday with a 37.51% gain persists in today's pre-market, indicating sustained growth for NVNI.
CHX	17.55%	The pre-market session on Wednesday saw a significant rise in CHAMPIONX CORP's (NASDAQ:CHX) shares, climbing 17.55% to $29.0. In the last year the share price dropped with 26.58%.
PHLT	17.45%	During Wednesday's pre-market session, PERFORMANT HEALTHCARE INC (NASDAQ:PHLT) exhibited strong growth, with the stock price climbing 17.45% to $2.76. In the last month the share price dropped with 20.61%.
GCTK	16.45%	GLUCOTRACK INC (NASDAQ:GCTK) experienced an impressive 16.45% increase in share price, reaching $0.2 during the pre-market session on Wednesday. In the last 3 months the stock lost 86.61%.

To see the full list of premarket gainers you can use our premarket gainers page.

Pre-market losers

Ticker	Change	Comment
WGS	-32.46%	Investors observed a 32.46% decline in GENEDX HOLDINGS CORP's (NASDAQ:WGS) stock price, which now stands at $79.0 during Wednesday's pre-market session. yesterday the company released their earnings. A press release (GeneDx Reports First Quarter 2025 Financial Results and Business Highlights) was released earlier today.
LITM	-31.33%	Wednesday's pre-market session showed a 31.33% decrease in the stock price of SNOW LAKE RESOURCES LTD (NASDAQ:LITM), reaching $0.3. In the last 3 months the share price dropped with 42.06%.
CYCC	-21.0%	CYCLACEL PHARMACEUTICALS INC's (NASDAQ:CYCC) shares fell 21.0% to $0.24 during Wednesday's pre-market session. Shareholders saw the stock price going 51.54% lower is the past 6 months.
SMCI	-18.17%	Despite yesterday's decline, SUPER MICRO COMPUTER INC (NASDAQ:SMCI) experienced a further 18.17% decrease in share price during Wednesday's pre-market session, reaching $29.46. In the last 3 months the share price increased with 26.23%.
IMUX	-17.97%	Investors observed a 17.97% decline in IMMUNIC INC's (NASDAQ:IMUX) stock price, which now stands at $1.05 during Wednesday's pre-market session. Following yesterday's gain of 14.29%, IMUX experiences a 17.97% decrease in today's pre-market session, indicating a pullback from the previous session's performance.
TENB	-16.57%	The stock price of TENABLE HOLDINGS INC (NASDAQ:TENB) is experiencing a decline of 16.57%, reaching $28.1 in today's pre-market session on Wednesday. Yesterday the company had a press release: Tenable Announces First Quarter 2025 Financial Results.
WNC	-14.66%	WABASH NATIONAL CORP's (NYSE:WNC) shares fell 14.66% to $8.5 during Wednesday's pre-market session. yesterday the company released their earnings. In the last 3 months the share price dropped with 36.15%.
SNAP	-13.97%	During Wednesday's pre-market session, the shares of SNAP INC - A (NYSE:SNAP) declined by 13.97%, reaching $7.82. Yesterday the company had a press release: Snap Inc. Announces First Quarter 2025 Financial Results.
NOVA	-13.66%	The stock price of SUNNOVA ENERGY INTERNATIONAL (NYSE:NOVA) is experiencing a decline of 13.66%, reaching $0.19 in today's pre-market session on Wednesday. The stock is trading 39.38% lower than a month ago.
ANTE	-13.13%	AIRNET TECHNOLOGY INC-ADR's (NASDAQ:ANTE) stock price recorded a 13.13% decrease, falling to $0.65. The stock is trading 61.72% higher than a month ago.

For the full premarket loser list go to our premarket losers page.