OptimizeRx Corp. (NASDAQ:OPRX) reported second-quarter 2025 financial results that significantly exceeded analyst expectations, driving a sharp positive reaction in after-hours trading. The healthcare technology company posted revenue of $29.2 million, a 55% year-over-year increase, and non-GAAP earnings per share (EPS) of $0.24, far surpassing consensus estimates of $0.0175 EPS and $22.7 million in revenue.
Key Financial Highlights vs. Estimates
- Revenue Beat: Reported $29.2M vs. estimated $22.7M (+28.7% above expectations)
- EPS Beat: Non-GAAP EPS of $0.24 vs. estimated $0.0175 (a substantial outperformance)
- Gross Profit Growth: Up 59% YoY to $18.6 million, reflecting improved operational efficiency.
The strong revenue growth was driven by increased engagement with pharmaceutical manufacturers and higher revenue retention rates. The company also highlighted an acceleration in AI-driven patient-finding technology adoption, contributing to the outperformance.
Market Reaction
Following the earnings release, OptimizeRx shares surged 15.2% in after-hours trading, indicating strong investor approval of the results. The market’s reaction suggests that the revenue and EPS beats, along with improved profitability, were well-received.
Updated Guidance and Outlook
OptimizeRx raised its full-year 2025 guidance, now expecting:
- Revenue: $104M–$108M (vs. analyst consensus of $105.4M)
- Adjusted EBITDA: $14.5M–$17.5M
This upward revision signals confidence in continued growth, particularly as contracted revenue has increased more than 30% year-over-year.
Operational and Financial Highlights
- Debt Reduction: Paid down $4.5 million in debt during Q2, exceeding scheduled payments.
- Cash Position: Ended the quarter with $16.6 million in cash and equivalents, up from $13.4 million at year-end 2024.
- Net Revenue Retention: 121%, indicating strong client retention and expansion.
Conclusion
OptimizeRx’s Q2 results demonstrate accelerating growth, profitability, and disciplined financial management. The raised guidance reinforces expectations of sustained momentum, supported by AI-driven solutions and deepening pharmaceutical partnerships.
For more detailed earnings estimates and historical performance, view the full earnings and estimates data here.
Disclaimer: This article is not investment advice. Investors should conduct their own research before making any financial decisions.


