Iterum Therapeutics PLC (NASDAQ:ITRM Reports Q2 2025 Earnings: Wider Loss Than Expected, Market Reacts Positively Ahead of Key Launch
Iterum Therapeutics PLC released its second-quarter 2025 financial results, revealing a net loss per share of -$0.16, missing analyst expectations of -$0.1122. Revenue for the quarter came in at $0, aligning with estimates. Despite the wider-than-expected loss, the stock saw a 4.15% pre-market surge, suggesting investor optimism around the company’s upcoming launch of ORLYNVAH™, its oral antibiotic for urinary tract infections, expected in August 2025.
Key Takeaways from the Earnings Report
- EPS Miss: The reported loss of -$0.16 per share was deeper than the consensus estimate of -$0.1122, reflecting continued R&D and pre-launch expenses.
- Revenue In Line: No revenue was recorded, matching expectations as the company has yet to commercialize its lead product.
- Cash Position: Iterum reiterated that its cash reserves will fund operations into 2026, providing a runway beyond the ORLYNVAH launch.
Market Reaction and Outlook
Despite the negative earnings surprise, the stock’s pre-market jump indicates that investors are focusing on the near-term catalyst—the upcoming launch of ORLYNVAH. The company did not provide specific financial guidance in the press release, but analysts project:
- Full-year 2025 revenue at $4.76 million, likely tied to initial ORLYNVAH sales.
- Q3 2025 EPS estimate of -$0.1122, suggesting continued losses as commercialization ramps up.
The positive price action suggests that the market is willing to overlook short-term losses in favor of potential revenue growth from ORLYNVAH’s launch.
Press Release Highlights
- ORLYNVAH Launch Imminent: The antibiotic is on track for an August 2025 rollout, marking Iterum’s transition to a commercial-stage company.
- Financial Stability: With cash extending into 2026, the company has sufficient liquidity to support initial commercialization efforts.
For a deeper look at Iterum’s earnings estimates and historical performance, visit Iterum Therapeutics Earnings & Estimates.
Disclaimer: This article is for informational purposes only and does not constitute investment advice. Investors should conduct their own research before making any financial decisions.


