HOLOGIC INC (NASDAQ:HOLX) reported financial results for its fiscal first quarter of 2026, delivering a mixed performance that fell short of Wall Street's expectations on the top and bottom lines. The medical technology company's stock saw a modest decline in after-hours trading following the release, reflecting investor disappointment with the quarterly miss.
Quarterly Performance Versus Estimates
The company reported revenue of $1.05 billion for the quarter ended December 27, 2025. While this represented a 2.5% increase over the prior year period, it came in below analyst consensus estimates of approximately $1.09 billion. On the profitability front, Hologic posted non-GAAP earnings per share (EPS) of $1.04. This figure also missed the mark, falling short of the $1.11 per share analysts had anticipated.
The key quarterly comparisons are as follows:
- Reported Revenue: $1.05 billion
- Estimated Revenue: ~$1.09 billion
- Variance: -4.0%
- Reported Non-GAAP EPS: $1.04
- Estimated Non-GAAP EPS: $1.11
- Variance: -6.3%
Market Reaction and Price Action
The market's immediate reaction to the earnings report was negative. Following the release, Hologic's stock traded lower in the after-hours session. This price action suggests investors were focused on the company's failure to meet quarterly forecasts. The negative sentiment extends a recent trend of weakness, with the stock showing slight declines over the past two-week period leading up to the earnings announcement.
Key Business Segment Highlights
Beyond the headline misses, the earnings press release detailed performance across Hologic's core business divisions, revealing areas of both strength and challenge.
- Diagnostics: Total revenue of $464.4 million decreased 1.3% year-over-year. A continued sharp decline in COVID-19 related revenue was a significant headwind. However, excluding COVID-19 sales, organic diagnostics revenue showed modest growth of 1.2%.
- Breast Health: Revenue grew 1.8% to $375.9 million. This growth was primarily driven by a strong 9.6% increase in Interventional Breast Solutions, offsetting a slight dip in Breast Imaging revenue.
- GYN Surgical: This was the standout segment, with revenue jumping 8.7% to $180.8 million. The growth was fueled by contributions from the acquired Gynesonics business, with organic surgical revenue still growing a healthy 3.2%.
- Financial Health: The company generated strong operating cash flow of $229.9 million, an increase of 21.4%. It ended the quarter with a robust cash position of $2.17 billion and a low adjusted net leverage ratio.
The Merger Context and Lack of Guidance
A critical element shaping the current investment narrative for Hologic is its pending acquisition. The company has scheduled a special meeting of stockholders for February 5, 2026, to vote on adopting the merger agreement with funds managed by Blackstone and TPG. As previously stated, due to this pending transaction, Hologic is not providing any financial guidance for fiscal 2026 and did not host a conference call to discuss the quarterly results.
This lack of forward-looking commentary from management makes it difficult to assess how the Q1 performance aligns with internal plans or the broader analyst model for the year. For context, current analyst consensus estimates project full-year fiscal 2026 revenue of approximately $4.38 billion and Q2 revenue of about $1.07 billion.
Conclusion
Hologic's first quarter presented a familiar story of a company navigating a post-pandemic normalization. Core businesses in Breast Health and GYN Surgical exhibited solid growth, but a larger-than-expected decline in the Diagnostics segment, coupled with broader margin pressures from tariff expenses, led to a double miss on revenue and earnings. The market's negative reaction underscores the high bar set for companies even during transitional periods. With the looming shareholder vote on its acquisition, Hologic's journey as a publicly traded company appears to be in its final chapters, leaving investors to weigh its standalone quarterly execution against the certainty of the pending buyout.
For a detailed look at Hologic's historical earnings and future analyst estimates, visit the Hologic earnings and estimates page.
Disclaimer: This article is for informational purposes only and does not constitute financial advice, an endorsement, or a recommendation to buy, sell, or hold any security. Investors should conduct their own research and consult with a qualified financial advisor before making any investment decisions.



