By Mill Chart
Last update: Nov 5, 2025
Charles River Laboratories International (NYSE:CRL) reported third-quarter financial results that narrowly surpassed analyst revenue expectations, though the company's overall sales remained essentially flat compared to the same period last year. The life sciences research firm posted revenue of $1.00 billion, slightly above the consensus estimate of $1.00 billion, while non-GAAP earnings per share of $2.43 exceeded the projected $2.36 per share.
Quarterly Performance Versus Expectations
The company's ability to beat both top and bottom-line estimates reflects stable demand for its early-stage research services despite ongoing challenges in the broader biopharmaceutical sector. While the revenue beat was modest, the earnings outperformance suggests effective cost management and operational execution during the quarter.
Key financial metrics from the quarter include:
Market Reaction and Price Action
Investors responded cautiously to the mixed results, with the stock showing minimal movement in pre-market trading. This muted reaction suggests the market had largely priced in the company's performance, recognizing both the earnings beat and the underlying challenges reflected in the year-over-year revenue decline. The stock's performance over recent weeks has been relatively stable, indicating that investors may be taking a wait-and-see approach toward the company's recovery timeline.
Updated 2025 Guidance
Management provided updated full-year guidance that reflects both optimism and caution. The company narrowed its revenue decline projection to between 1.5% and 0.5%, improved from the previous range of 2.5% to 0.5%. More notably, the non-GAAP EPS guidance was raised to $10.10-$10.30, compared to the prior range of $9.90-$10.30.
The updated guidance compares favorably to analyst expectations:
Segment Performance Breakdown
The company's results showed significant variation across its business segments, highlighting both areas of strength and ongoing challenges:
Research Models and Services (RMS) demonstrated strong performance with:
Discovery and Safety Assessment (DSA), the company's largest segment, experienced:
Manufacturing Solutions reported:
Management Commentary and Outlook
James C. Foster, Chair, President and CEO, noted that "positive signals are beginning to emerge which indicate that the industry may be on a path towards recovery," while acknowledging that "sustained improvement in our business will take time." The company remains cautious given ongoing uncertainty in the healthcare sector but emphasized its focus on differentiating through scientific innovation and gaining additional share of client drug development programs.
The company's restructuring initiatives contributed to improved GAAP operating margins, which increased to 13.3% from 11.6% in the prior year period. However, venture capital and strategic investment losses of $0.33 per share negatively impacted GAAP earnings compared to a $0.03 gain in the same quarter last year.
For more detailed earnings analysis and future estimates, readers can review the earnings estimates page for CRL.
Disclaimer: This article presents an objective analysis of Charles River Laboratories' financial results and market performance and does not constitute investment advice. Investors should conduct their own research and consult with financial advisors before making investment decisions.
171.5
-2 (-1.15%)
Find more stocks in the Stock Screener


