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IONIS PHARMACEUTICALS INC (NASDAQ:IONS) Presents a High-Probability Technical Breakout Setup

By Mill Chart

Last update: Aug 30, 2025

For technical investors looking for breakout chances, the method often requires finding stocks with both good basic technical condition and present consolidation patterns that indicate coming price action. This system uses two main measures: the Technical Rating, which reviews the stock's general trend force and momentum, and the Setup Quality Rating, which checks how suitably the stock is placed for a possible breakout using recent price movement, support zones, and volatility tightening. Stocks with high marks on both measures usually show good risk-reward situations, as they are not only in clear uptrends but also consolidating in a way that gives specific entry and exit places.

IONIS PHARMACEUTICALS INC (NASDAQ:IONS) appears as a candidate matching this plan, based on its newest technical analysis report. The report gives the stock a Technical Rating of 7, showing a firm uptrend with good long-term and short-term momentum. This rating shows several helpful factors, including the stock trading in the high part of its 52-week range, with increasing moving averages like the SMA50, SMA100, and SMA200 all moving up. Although it is a bit behind the wider market, with the S&P500 showing good trends in both the short and long term, IONS still does better than 61% of all stocks and 63% of its biotechnology industry friends, showing decent relative force. These technical bases are important for breakout setups, as they suggest the stock has basic momentum that might push it higher once it moves out of its present range.

IONS Stock Chart

Adding to its technical condition, IONS has a Setup Rating of 9, pointing out a very good consolidation pattern. The stock has been trading inside a set range between about $40.03 and $44.99 over the last month, with recent price movement staying near the middle of this range. This action shows lower volatility and the building of a support area between $40.57 and $42.51, made by a mix of trendlines and moving averages across daily and weekly timeframes. Also, the existence of a pocket pivot signal and clear gathering by big players further supports the setup quality, hinting at institutional interest. These parts are key for breakout plans because they give a specific support zone for setting stop-loss orders and indicate that the stock is tightening for a possible upward move.

The mix of a firm Technical Rating and high Setup Rating makes IONS an interesting candidate for technical breakout investors. The suggested trade setup proposes an entry point just above the resistance zone at $43.79, with a stop-loss order set below the main support at $41.70. These levels provide a measured risk of about 4.78%, matching with careful position sizing rules. For investors wanting to look into similar chances, the Technical Breakout Setups screen offers daily updated results using the same strict standards.

Disclaimer: This analysis is for informational purposes only and does not constitute investment advice. Investors should conduct their own research and consider their risk tolerance before making any trading decisions.

IONIS PHARMACEUTICALS INC

NASDAQ:IONS (9/24/2025, 11:43:33 AM)

63.315

+0.74 (+1.19%)



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