Which S&P500 stocks are moving on Wednesday?
By Mill Chart
Last update: Oct 1, 2025
Curious about the top performers within the S&P500 index in the middle of the day on Wednesday? Dive into the list of today's session's top gainers and losers for a comprehensive overview.
Gainers
| Ticker | Change | Comment |
|---|---|---|
| AES | 15.16% | AES CORP's (NYSE:AES) stock price displayed strong growth, advancing 15.16% and reaching $15.15 during Wednesday's session. The stock is trading 22.08% higher than 6 months ago. |
| REGN | 8.48% | REGENERON PHARMACEUTICALS's (NASDAQ:REGN) stock price is advancing with 8.48% to a price of $609.95. Yesterday the company had a press release: Regeneron to Report Third Quarter 2025 Financial and Operating Results and Host Conference Call and Webcast on October 28, 2025. |
| BIIB | 8.03% | Positive market sentiment drove BIOGEN INC's (NASDAQ:BIIB) stock price up by 8.03% to $151.34 during Wednesday's session. Shareholders saw the stock price going 24.56% lower is the past year. |
| MRNA | 7.78% | MODERNA INC's (NASDAQ:MRNA) shares soared 7.78% to $27.84 during Wednesday's session. The stock is trading 57.09% lower than a year ago. |
| TMO | 7.51% | Positive market sentiment drove THERMO FISHER SCIENTIFIC INC's (NYSE:TMO) stock price up by 7.51% to $521.44 during Wednesday's session. Yesterday the company had a press release: Thermo Fisher Scientific Prices Offering of USD-Denominated Senior Notes. |
| MU | 7.33% | MICRON TECHNOLOGY INC (NASDAQ:MU) experienced a significant 7.33% increase, reaching $179.59 during Wednesday's session. In the last month the share price increased with 41.22%. |
| LLY | 6.83% | Exciting news for ELI LILLY & CO (NYSE:LLY) as its stock price surged 6.83% to $815.11 during Wednesday's session. |
| CRL | 6.72% | Positive market sentiment drove CHARLES RIVER LABORATORIES's (NYSE:CRL) stock price up by 6.72% to $166.97 during Wednesday's session. |
| LW | 6.18% | With a 6.18% surge, LAMB WESTON HOLDINGS INC's (NYSE:LW) stock price reached $61.67 during Wednesday's session, signaling positive momentum. A press release (Lamb Weston Reports First Quarter Fiscal 2026 Results; Reaffirms Fiscal Year 2026 Outlook) was released yesterday. |
| AMGN | 6.07% | Exciting news for AMGEN INC (NASDAQ:AMGN) as its stock price surged 6.07% to $299.34 during Wednesday's session. |
To see the full list of top gainers you can use our top gainers page.
Losers
| Ticker | Change | Comment |
|---|---|---|
| CTVA | -7.93% | Investors witnessed a 7.93% drop in CORTEVA INC's (NYSE:CTVA) stock price, which closed at $62.27 during Wednesday's session. Shareholders saw the stock price going 21.22% higher is the past 6 months. |
| IDXX | -5.75% | The market experienced a downward movement in IDEXX LABORATORIES INC's (NASDAQ:IDXX) stock price, closing at $602.13 with a 5.75% decrease during Wednesday's session. In the last 6 months the stock gained 62.27%. |
| NWS | -5.56% | NEWS CORP - CLASS B's (NASDAQ:NWS) stock price decreased by 5.56% to $32.63. The stock is trading 24.73% higher than 6 months ago. |
| DXCM | -4.95% | Investors witnessed a 4.95% drop in DEXCOM INC's (NASDAQ:DXCM) stock price, which closed at $63.96 during Wednesday's session. |
| NWSA | -4.74% | There was a downturn in NEWS CORP - CLASS A's (NASDAQ:NWSA) shares, as they experienced a 4.74% decline, closing at $29.25 during Wednesday's session. The stock is trading 24.94% higher than 6 months ago. |
| IPG | -4.69% | INTERPUBLIC GROUP OF COS INC's (NYSE:IPG) stock price encountered a 4.69% decline, reaching $26.6 during Wednesday's session. |
| OMC | -4.49% | There was a notable decline in OMNICOM GROUP's (NYSE:OMC) shares, as they dropped 4.49% to $77.87 during Wednesday's session. |
| IT | -4.18% | GARTNER INC's (NYSE:IT) shares fell 4.18% to $251.88 during Wednesday's session. The stock is trading 34.33% lower than 3 months ago. |
| SYK | -4.07% | STRYKER CORP's (NYSE:SYK) stock price encountered a 4.07% decline, reaching $354.64 during Wednesday's session. Earlier today the company had a press release: Stryker to announce financial results for its third quarter of fiscal year 2025. |
| DG | -4.03% | DOLLAR GENERAL CORP's (NYSE:DG) stock price encountered a 4.03% decline, reaching $99.19 during Wednesday's session. In the last year the share price increased with 22.53%. |
To see the full list of top losers you can use our top losers page.
NASDAQ:AMGN (10/1/2025, 12:27:10 PM)
298.575
+16.38 (+5.8%)
NASDAQ:BIIB (10/1/2025, 12:26:17 PM)
151.185
+11.1 (+7.93%)
NYSE:CRL (10/1/2025, 12:26:57 PM)
166.52
+10.06 (+6.43%)
NASDAQ:REGN (10/1/2025, 12:26:53 PM)
608.035
+45.76 (+8.14%)
NASDAQ:IDXX (10/1/2025, 12:27:03 PM)
600.595
-38.29 (-5.99%)
NYSE:LLY (10/1/2025, 12:27:06 PM)
814.93
+51.93 (+6.81%)
NASDAQ:DXCM (10/1/2025, 12:27:08 PM)
63.83
-3.46 (-5.14%)
NYSE:SYK (10/1/2025, 12:27:00 PM)
354.16
-15.51 (-4.2%)
NYSE:IPG (10/1/2025, 12:27:10 PM)
26.61
-1.3 (-4.66%)
NYSE:OMC (10/1/2025, 12:27:10 PM)
77.88
-3.65 (-4.48%)
NASDAQ:NWSA (10/1/2025, 12:27:00 PM)
29.255
-1.46 (-4.74%)
NYSE:IT (10/1/2025, 12:27:08 PM)
251.485
-11.38 (-4.33%)
NYSE:TMO (10/1/2025, 12:26:53 PM)
521.695
+36.68 (+7.56%)
NASDAQ:MU (10/1/2025, 12:27:08 PM)
179.44
+12.12 (+7.24%)
NYSE:AES (10/1/2025, 12:27:08 PM)
15.14
+1.98 (+15.05%)
NYSE:DG (10/1/2025, 12:27:08 PM)
98.995
-4.35 (-4.21%)
NASDAQ:NWS (10/1/2025, 12:26:51 PM)
32.635
-1.91 (-5.54%)
NYSE:LW (10/1/2025, 12:27:03 PM)
61.53
+3.45 (+5.94%)
NASDAQ:MRNA (10/1/2025, 12:27:02 PM)
27.8051
+1.98 (+7.65%)
NYSE:CTVA (10/1/2025, 12:27:05 PM)
62.25
-5.38 (-7.96%)
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