Which S&P500 stocks are moving on Wednesday?
By Mill Chart
Last update: Oct 1, 2025
Curious about the top performers within the S&P500 index in the middle of the day on Wednesday? Dive into the list of today's session's top gainers and losers for a comprehensive overview.
Gainers
| Ticker | Change | Comment |
|---|---|---|
| AES | 15.16% | AES CORP's (NYSE:AES) stock price displayed strong growth, advancing 15.16% and reaching $15.15 during Wednesday's session. The stock is trading 22.08% higher than 6 months ago. |
| REGN | 8.48% | REGENERON PHARMACEUTICALS's (NASDAQ:REGN) stock price is advancing with 8.48% to a price of $609.95. Yesterday the company had a press release: Regeneron to Report Third Quarter 2025 Financial and Operating Results and Host Conference Call and Webcast on October 28, 2025. |
| BIIB | 8.03% | Positive market sentiment drove BIOGEN INC's (NASDAQ:BIIB) stock price up by 8.03% to $151.34 during Wednesday's session. Shareholders saw the stock price going 24.56% lower is the past year. |
| MRNA | 7.78% | MODERNA INC's (NASDAQ:MRNA) shares soared 7.78% to $27.84 during Wednesday's session. The stock is trading 57.09% lower than a year ago. |
| TMO | 7.51% | Positive market sentiment drove THERMO FISHER SCIENTIFIC INC's (NYSE:TMO) stock price up by 7.51% to $521.44 during Wednesday's session. Yesterday the company had a press release: Thermo Fisher Scientific Prices Offering of USD-Denominated Senior Notes. |
| MU | 7.33% | MICRON TECHNOLOGY INC (NASDAQ:MU) experienced a significant 7.33% increase, reaching $179.59 during Wednesday's session. In the last month the share price increased with 41.22%. |
| LLY | 6.83% | Exciting news for ELI LILLY & CO (NYSE:LLY) as its stock price surged 6.83% to $815.11 during Wednesday's session. |
| CRL | 6.72% | Positive market sentiment drove CHARLES RIVER LABORATORIES's (NYSE:CRL) stock price up by 6.72% to $166.97 during Wednesday's session. |
| LW | 6.18% | With a 6.18% surge, LAMB WESTON HOLDINGS INC's (NYSE:LW) stock price reached $61.67 during Wednesday's session, signaling positive momentum. A press release (Lamb Weston Reports First Quarter Fiscal 2026 Results; Reaffirms Fiscal Year 2026 Outlook) was released yesterday. |
| AMGN | 6.07% | Exciting news for AMGEN INC (NASDAQ:AMGN) as its stock price surged 6.07% to $299.34 during Wednesday's session. |
To see the full list of top gainers you can use our top gainers page.
Losers
| Ticker | Change | Comment |
|---|---|---|
| CTVA | -7.93% | Investors witnessed a 7.93% drop in CORTEVA INC's (NYSE:CTVA) stock price, which closed at $62.27 during Wednesday's session. Shareholders saw the stock price going 21.22% higher is the past 6 months. |
| IDXX | -5.75% | The market experienced a downward movement in IDEXX LABORATORIES INC's (NASDAQ:IDXX) stock price, closing at $602.13 with a 5.75% decrease during Wednesday's session. In the last 6 months the stock gained 62.27%. |
| NWS | -5.56% | NEWS CORP - CLASS B's (NASDAQ:NWS) stock price decreased by 5.56% to $32.63. The stock is trading 24.73% higher than 6 months ago. |
| DXCM | -4.95% | Investors witnessed a 4.95% drop in DEXCOM INC's (NASDAQ:DXCM) stock price, which closed at $63.96 during Wednesday's session. |
| NWSA | -4.74% | There was a downturn in NEWS CORP - CLASS A's (NASDAQ:NWSA) shares, as they experienced a 4.74% decline, closing at $29.25 during Wednesday's session. The stock is trading 24.94% higher than 6 months ago. |
| IPG | -4.69% | INTERPUBLIC GROUP OF COS INC's (NYSE:IPG) stock price encountered a 4.69% decline, reaching $26.6 during Wednesday's session. |
| OMC | -4.49% | There was a notable decline in OMNICOM GROUP's (NYSE:OMC) shares, as they dropped 4.49% to $77.87 during Wednesday's session. |
| IT | -4.18% | GARTNER INC's (NYSE:IT) shares fell 4.18% to $251.88 during Wednesday's session. The stock is trading 34.33% lower than 3 months ago. |
| SYK | -4.07% | STRYKER CORP's (NYSE:SYK) stock price encountered a 4.07% decline, reaching $354.64 during Wednesday's session. Earlier today the company had a press release: Stryker to announce financial results for its third quarter of fiscal year 2025. |
| DG | -4.03% | DOLLAR GENERAL CORP's (NYSE:DG) stock price encountered a 4.03% decline, reaching $99.19 during Wednesday's session. In the last year the share price increased with 22.53%. |
To see the full list of top losers you can use our top losers page.
NASDAQ:AMGN (12/1/2025, 9:51:10 AM)
342.73
-2.73 (-0.79%)
NASDAQ:BIIB (12/1/2025, 9:50:52 AM)
181.01
-1.08 (-0.59%)
NYSE:CRL (12/1/2025, 9:51:00 AM)
180.015
+1.88 (+1.05%)
NASDAQ:REGN (12/1/2025, 9:51:07 AM)
775.4
-4.79 (-0.61%)
NASDAQ:IDXX (12/1/2025, 9:51:06 AM)
739.7
-13.18 (-1.75%)
NYSE:LLY (12/1/2025, 9:51:09 AM)
1074.33
-1.14 (-0.11%)
NASDAQ:DXCM (12/1/2025, 9:51:02 AM)
62.63
-0.84 (-1.32%)
NYSE:SYK (12/1/2025, 9:51:05 AM)
371.135
-0.05 (-0.01%)
24.57
-0.49 (-1.96%)
NYSE:OMC (12/1/2025, 9:51:01 AM)
72.215
+0.59 (+0.83%)
NASDAQ:NWSA (12/1/2025, 9:50:57 AM)
25.675
0 (-0.02%)
NYSE:IT (12/1/2025, 9:50:47 AM)
232.185
-0.56 (-0.24%)
NYSE:TMO (12/1/2025, 9:51:10 AM)
594.29
+3.46 (+0.59%)
NASDAQ:MU (12/1/2025, 9:51:10 AM)
235.235
-1.24 (-0.53%)
NYSE:AES (12/1/2025, 9:51:04 AM)
14.048
-0.01 (-0.09%)
NYSE:DG (12/1/2025, 9:51:06 AM)
109.77
+0.28 (+0.26%)
NASDAQ:NWS (12/1/2025, 9:50:55 AM)
29.3395
-0.09 (-0.31%)
NYSE:LW (12/1/2025, 9:51:01 AM)
59.12
+0.06 (+0.1%)
NASDAQ:MRNA (12/1/2025, 9:51:01 AM)
25.05
-0.93 (-3.58%)
NYSE:CTVA (12/1/2025, 9:51:00 AM)
67.597
+0.31 (+0.46%)
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