Which S&P500 stocks are moving on Wednesday?

By Mill Chart - Last update: Oct 1, 2025

Curious about the top performers within the S&P500 index in the middle of the day on Wednesday? Dive into the list of today's session's top gainers and losers for a comprehensive overview.


topmovers

Gainers

TickerChangeComment
AES15.16%AES CORP's (NYSE:AES) stock price displayed strong growth, advancing 15.16% and reaching $15.15 during Wednesday's session. The stock is trading 22.08% higher than 6 months ago.
REGN8.48%REGENERON PHARMACEUTICALS's (NASDAQ:REGN) stock price is advancing with 8.48% to a price of $609.95. Yesterday the company had a press release: Regeneron to Report Third Quarter 2025 Financial and Operating Results and Host Conference Call and Webcast on October 28, 2025.
BIIB8.03%Positive market sentiment drove BIOGEN INC's (NASDAQ:BIIB) stock price up by 8.03% to $151.34 during Wednesday's session. Shareholders saw the stock price going 24.56% lower is the past year.
MRNA7.78%MODERNA INC's (NASDAQ:MRNA) shares soared 7.78% to $27.84 during Wednesday's session. The stock is trading 57.09% lower than a year ago.
TMO7.51%Positive market sentiment drove THERMO FISHER SCIENTIFIC INC's (NYSE:TMO) stock price up by 7.51% to $521.44 during Wednesday's session. Yesterday the company had a press release: Thermo Fisher Scientific Prices Offering of USD-Denominated Senior Notes.
MU7.33%MICRON TECHNOLOGY INC (NASDAQ:MU) experienced a significant 7.33% increase, reaching $179.59 during Wednesday's session. In the last month the share price increased with 41.22%.
LLY6.83%Exciting news for ELI LILLY & CO (NYSE:LLY) as its stock price surged 6.83% to $815.11 during Wednesday's session.
CRL6.72%Positive market sentiment drove CHARLES RIVER LABORATORIES's (NYSE:CRL) stock price up by 6.72% to $166.97 during Wednesday's session.
LW6.18%With a 6.18% surge, LAMB WESTON HOLDINGS INC's (NYSE:LW) stock price reached $61.67 during Wednesday's session, signaling positive momentum. A press release (Lamb Weston Reports First Quarter Fiscal 2026 Results; Reaffirms Fiscal Year 2026 Outlook) was released yesterday.
AMGN6.07%Exciting news for AMGEN INC (NASDAQ:AMGN) as its stock price surged 6.07% to $299.34 during Wednesday's session.

To see the full list of top gainers you can use our top gainers page.

Losers

TickerChangeComment
CTVA-7.93%Investors witnessed a 7.93% drop in CORTEVA INC's (NYSE:CTVA) stock price, which closed at $62.27 during Wednesday's session. Shareholders saw the stock price going 21.22% higher is the past 6 months.
IDXX-5.75%The market experienced a downward movement in IDEXX LABORATORIES INC's (NASDAQ:IDXX) stock price, closing at $602.13 with a 5.75% decrease during Wednesday's session. In the last 6 months the stock gained 62.27%.
NWS-5.56%NEWS CORP - CLASS B's (NASDAQ:NWS) stock price decreased by 5.56% to $32.63. The stock is trading 24.73% higher than 6 months ago.
DXCM-4.95%Investors witnessed a 4.95% drop in DEXCOM INC's (NASDAQ:DXCM) stock price, which closed at $63.96 during Wednesday's session.
NWSA-4.74%There was a downturn in NEWS CORP - CLASS A's (NASDAQ:NWSA) shares, as they experienced a 4.74% decline, closing at $29.25 during Wednesday's session. The stock is trading 24.94% higher than 6 months ago.
IPG-4.69%INTERPUBLIC GROUP OF COS INC's (NYSE:IPG) stock price encountered a 4.69% decline, reaching $26.6 during Wednesday's session.
OMC-4.49%There was a notable decline in OMNICOM GROUP's (NYSE:OMC) shares, as they dropped 4.49% to $77.87 during Wednesday's session.
IT-4.18%GARTNER INC's (NYSE:IT) shares fell 4.18% to $251.88 during Wednesday's session. The stock is trading 34.33% lower than 3 months ago.
SYK-4.07%STRYKER CORP's (NYSE:SYK) stock price encountered a 4.07% decline, reaching $354.64 during Wednesday's session. Earlier today the company had a press release: Stryker to announce financial results for its third quarter of fiscal year 2025.
DG-4.03%DOLLAR GENERAL CORP's (NYSE:DG) stock price encountered a 4.03% decline, reaching $99.19 during Wednesday's session. In the last year the share price increased with 22.53%.

To see the full list of top losers you can use our top losers page.

AMGEN INC

NASDAQ:AMGN (2/25/2026, 8:00:01 PM)

After market: 384.02 -0.31 (-0.08%)

384.33

+1.46 (+0.38%)


BIOGEN INC

NASDAQ:BIIB (2/25/2026, 8:00:02 PM)

After market: 190.73 0 (0%)

190.73

-4.4 (-2.25%)


CHARLES RIVER LABORATORIES

NYSE:CRL (2/25/2026, 8:04:00 PM)

After market: 167.56 0 (0%)

167.56

+1.5 (+0.9%)


REGENERON PHARMACEUTICALS

NASDAQ:REGN (2/25/2026, 8:00:02 PM)

After market: 784.515 +0.24 (+0.03%)

784.28

+12.09 (+1.57%)


IDEXX LABORATORIES INC

NASDAQ:IDXX (2/25/2026, 8:20:36 PM)

After market: 657.38 0 (0%)

657.38

+8.15 (+1.26%)


ELI LILLY & CO

NYSE:LLY (2/25/2026, 10:41:12 PM)

Premarket: 1030.43 +1.6 (+0.16%)

1028.83

-13.32 (-1.28%)


DEXCOM INC

NASDAQ:DXCM (2/25/2026, 8:05:58 PM)

After market: 73.16 0 (0%)

73.16

+0.07 (+0.1%)


STRYKER CORP

NYSE:SYK (2/25/2026, 8:04:00 PM)

After market: 384.03 0 (0%)

384.03

+2.7 (+0.71%)


INTERPUBLIC GROUP OF COS INC

NYSE:IPG (11/26/2025, 8:04:00 PM)

After market: 24.57 0 (0%)

24.57

-0.49 (-1.96%)


OMNICOM GROUP

NYSE:OMC (2/25/2026, 8:04:00 PM)

After market: 82.68 -0.03 (-0.04%)

82.71

+0.25 (+0.3%)


NEWS CORP - CLASS A

NASDAQ:NWSA (2/25/2026, 8:00:02 PM)

After market: 23.62 +0.04 (+0.17%)

23.58

+0.4 (+1.73%)


GARTNER INC

NYSE:IT (2/25/2026, 8:21:58 PM)

After market: 149.34 0 (0%)

149.34

+2 (+1.36%)


THERMO FISHER SCIENTIFIC INC

NYSE:TMO (2/25/2026, 8:04:00 PM)

After market: 514 +0.32 (+0.06%)

513.68

-1.92 (-0.37%)


MICRON TECHNOLOGY INC

NASDAQ:MU (2/25/2026, 8:00:01 PM)

Premarket: 430.45 +1.45 (+0.34%)

429

+10.99 (+2.63%)


AES CORP

NYSE:AES (2/25/2026, 8:04:00 PM)

Premarket: 16.46 +0.09 (+0.55%)

16.37

+0.1 (+0.61%)


DOLLAR GENERAL CORP

NYSE:DG (2/25/2026, 8:05:07 PM)

After market: 156.157 +1.37 (+0.88%)

154.79

+0.83 (+0.54%)


NEWS CORP - CLASS B

NASDAQ:NWS (2/25/2026, 8:00:02 PM)

Premarket: 26.24 -0.02 (-0.08%)

26.26

+0.22 (+0.84%)


LAMB WESTON HOLDINGS INC

NYSE:LW (2/25/2026, 8:26:50 PM)

Premarket: 47.25 +0.17 (+0.36%)

47.08

-0.88 (-1.83%)


MODERNA INC

NASDAQ:MRNA (2/25/2026, 8:00:01 PM)

Premarket: 51.05 -0.32 (-0.62%)

51.37

+0.85 (+1.68%)


CORTEVA INC

NYSE:CTVA (2/25/2026, 8:04:00 PM)

After market: 76.82 -0.85 (-1.09%)

77.67

-0.3 (-0.38%)



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