Which S&P500 stocks are moving on Wednesday?
By Mill Chart
Last update: Oct 1, 2025
Curious about the top performers within the S&P500 index in the middle of the day on Wednesday? Dive into the list of today's session's top gainers and losers for a comprehensive overview.
Gainers
| Ticker | Change | Comment |
|---|---|---|
| AES | 15.16% | AES CORP's (NYSE:AES) stock price displayed strong growth, advancing 15.16% and reaching $15.15 during Wednesday's session. The stock is trading 22.08% higher than 6 months ago. |
| REGN | 8.48% | REGENERON PHARMACEUTICALS's (NASDAQ:REGN) stock price is advancing with 8.48% to a price of $609.95. Yesterday the company had a press release: Regeneron to Report Third Quarter 2025 Financial and Operating Results and Host Conference Call and Webcast on October 28, 2025. |
| BIIB | 8.03% | Positive market sentiment drove BIOGEN INC's (NASDAQ:BIIB) stock price up by 8.03% to $151.34 during Wednesday's session. Shareholders saw the stock price going 24.56% lower is the past year. |
| MRNA | 7.78% | MODERNA INC's (NASDAQ:MRNA) shares soared 7.78% to $27.84 during Wednesday's session. The stock is trading 57.09% lower than a year ago. |
| TMO | 7.51% | Positive market sentiment drove THERMO FISHER SCIENTIFIC INC's (NYSE:TMO) stock price up by 7.51% to $521.44 during Wednesday's session. Yesterday the company had a press release: Thermo Fisher Scientific Prices Offering of USD-Denominated Senior Notes. |
| MU | 7.33% | MICRON TECHNOLOGY INC (NASDAQ:MU) experienced a significant 7.33% increase, reaching $179.59 during Wednesday's session. In the last month the share price increased with 41.22%. |
| LLY | 6.83% | Exciting news for ELI LILLY & CO (NYSE:LLY) as its stock price surged 6.83% to $815.11 during Wednesday's session. |
| CRL | 6.72% | Positive market sentiment drove CHARLES RIVER LABORATORIES's (NYSE:CRL) stock price up by 6.72% to $166.97 during Wednesday's session. |
| LW | 6.18% | With a 6.18% surge, LAMB WESTON HOLDINGS INC's (NYSE:LW) stock price reached $61.67 during Wednesday's session, signaling positive momentum. A press release (Lamb Weston Reports First Quarter Fiscal 2026 Results; Reaffirms Fiscal Year 2026 Outlook) was released yesterday. |
| AMGN | 6.07% | Exciting news for AMGEN INC (NASDAQ:AMGN) as its stock price surged 6.07% to $299.34 during Wednesday's session. |
To see the full list of top gainers you can use our top gainers page.
Losers
| Ticker | Change | Comment |
|---|---|---|
| CTVA | -7.93% | Investors witnessed a 7.93% drop in CORTEVA INC's (NYSE:CTVA) stock price, which closed at $62.27 during Wednesday's session. Shareholders saw the stock price going 21.22% higher is the past 6 months. |
| IDXX | -5.75% | The market experienced a downward movement in IDEXX LABORATORIES INC's (NASDAQ:IDXX) stock price, closing at $602.13 with a 5.75% decrease during Wednesday's session. In the last 6 months the stock gained 62.27%. |
| NWS | -5.56% | NEWS CORP - CLASS B's (NASDAQ:NWS) stock price decreased by 5.56% to $32.63. The stock is trading 24.73% higher than 6 months ago. |
| DXCM | -4.95% | Investors witnessed a 4.95% drop in DEXCOM INC's (NASDAQ:DXCM) stock price, which closed at $63.96 during Wednesday's session. |
| NWSA | -4.74% | There was a downturn in NEWS CORP - CLASS A's (NASDAQ:NWSA) shares, as they experienced a 4.74% decline, closing at $29.25 during Wednesday's session. The stock is trading 24.94% higher than 6 months ago. |
| IPG | -4.69% | INTERPUBLIC GROUP OF COS INC's (NYSE:IPG) stock price encountered a 4.69% decline, reaching $26.6 during Wednesday's session. |
| OMC | -4.49% | There was a notable decline in OMNICOM GROUP's (NYSE:OMC) shares, as they dropped 4.49% to $77.87 during Wednesday's session. |
| IT | -4.18% | GARTNER INC's (NYSE:IT) shares fell 4.18% to $251.88 during Wednesday's session. The stock is trading 34.33% lower than 3 months ago. |
| SYK | -4.07% | STRYKER CORP's (NYSE:SYK) stock price encountered a 4.07% decline, reaching $354.64 during Wednesday's session. Earlier today the company had a press release: Stryker to announce financial results for its third quarter of fiscal year 2025. |
| DG | -4.03% | DOLLAR GENERAL CORP's (NYSE:DG) stock price encountered a 4.03% decline, reaching $99.19 during Wednesday's session. In the last year the share price increased with 22.53%. |
To see the full list of top losers you can use our top losers page.
NASDAQ:AMGN (11/7/2025, 9:57:09 AM)
317.77
+2.18 (+0.69%)
NASDAQ:BIIB (11/7/2025, 9:57:07 AM)
154.98
-1.76 (-1.12%)
NYSE:CRL (11/7/2025, 9:57:01 AM)
168.06
-2.82 (-1.65%)
NASDAQ:REGN (11/7/2025, 9:57:09 AM)
643.76
-3.11 (-0.48%)
NASDAQ:IDXX (11/7/2025, 9:55:43 AM)
706.81
-6.93 (-0.97%)
NYSE:LLY (11/7/2025, 9:57:09 AM)
910.51
-26.93 (-2.87%)
NASDAQ:DXCM (11/7/2025, 9:57:06 AM)
56.476
-1.54 (-2.66%)
NYSE:SYK (11/7/2025, 9:57:07 AM)
355.14
+1.33 (+0.38%)
NYSE:IPG (11/7/2025, 9:57:08 AM)
25.25
+0.22 (+0.88%)
NYSE:OMC (11/7/2025, 9:57:08 AM)
73.675
+0.69 (+0.94%)
NASDAQ:NWSA (11/7/2025, 9:56:57 AM)
26.035
+0.96 (+3.81%)
NYSE:IT (11/7/2025, 9:56:40 AM)
227.295
+0.85 (+0.38%)
NYSE:TMO (11/7/2025, 9:57:06 AM)
567.39
+1.41 (+0.25%)
NASDAQ:MU (11/7/2025, 9:57:09 AM)
240.19
+1.86 (+0.78%)
NYSE:AES (11/7/2025, 9:57:05 AM)
13.905
-0.29 (-2.01%)
NYSE:DG (11/7/2025, 9:57:08 AM)
96.7
+0.76 (+0.79%)
NASDAQ:NWS (11/7/2025, 9:56:52 AM)
29.595
+1.11 (+3.92%)
NYSE:LW (11/7/2025, 9:56:39 AM)
61.87
-0.02 (-0.03%)
NASDAQ:MRNA (11/7/2025, 9:57:07 AM)
23.96
-0.37 (-1.52%)
NYSE:CTVA (11/7/2025, 9:57:03 AM)
63.47
+0.32 (+0.51%)
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