| Jan 17, 2026 | Forbes Alexandria | Option Excercise | 310000 | | $ 0.00 |
| Jan 17, 2026 | Forbes Alexandria | Option Excercise | 163916 | 7.42 | $ 1,216,256.72 |
| Jan 17, 2026 | Zeldin Robert K | Option Excercise | 35000 | | $ 0.00 |
| Jan 17, 2026 | Zeldin Robert K | Option Excercise | 13951 | 7.42 | $ 103,516.42 |
| Jan 17, 2026 | Giroux Richard | Option Excercise | 310000 | | $ 0.00 |
| Jan 17, 2026 | Giroux Richard | Option Excercise | 163916 | 7.42 | $ 1,216,256.72 |
| Jan 17, 2026 | Wollin Robert J | Option Excercise | 50000 | | $ 0.00 |
| Jan 17, 2026 | Wollin Robert J | Option Excercise | 27206 | 7.42 | $ 201,868.52 |
| Jan 17, 2026 | Naylor Stuart | Option Excercise | 75000 | | $ 0.00 |
| Jan 17, 2026 | Naylor Stuart | Option Excercise | 35250 | 7.42 | $ 261,555.00 |
| Jan 7, 2026 | Wollin Robert J | Option Excercise | 7500 | | $ 0.00 |
| Jan 7, 2026 | Wollin Robert J | Option Excercise | 4364 | 7.73 | $ 33,733.72 |
| Jan 7, 2026 | Naylor Stuart | Option Excercise | 37500 | | $ 0.00 |
| Jan 7, 2026 | Naylor Stuart | Option Excercise | 17625 | 7.73 | $ 136,241.25 |
| Jan 7, 2026 | Giroux Richard | Option Excercise | 52500 | | $ 0.00 |
| Jan 7, 2026 | Giroux Richard | Option Excercise | 28822 | 7.73 | $ 222,794.06 |
| Jan 7, 2026 | Forbes Alexandria | Option Excercise | 62500 | | $ 0.00 |
| Jan 7, 2026 | Forbes Alexandria | Option Excercise | 34074 | 7.73 | $ 263,392.02 |
| Jan 7, 2026 | Zeldin Robert K | Option Excercise | 17500 | | $ 0.00 |
| Jan 7, 2026 | Zeldin Robert K | Option Excercise | 6729 | 7.73 | $ 52,015.17 |
| Dec 31, 2025 | PERCEPTIVE ADVISORS LLC | Other Disposition | 2300000 | 7.91 | $ 18,193,000.00 |
| Dec 31, 2025 | EDELMAN JOSEPH | Other Disposition | 2300000 | 7.91 | $ 18,193,000.00 |
| Dec 31, 2025 | PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | Other Disposition | 2300000 | 7.91 | $ 18,193,000.00 |
| Dec 23, 2025 | Forbes Alexandria | Other Disposition | 6250 | 0.00 | $ 0.00 |
| Nov 20, 2025 | Wollin Robert J | Other Disposition | 5000 | 0.00 | $ 0.00 |
| Oct 21, 2025 | Giroux Richard | Open Market Sale | 24000 | 8.87 | $ 212,880.00 |
| Oct 7, 2025 | Forbes Alexandria | Open Market Sale | 47500 | 8.39 | $ 398,525.00 |
| Jul 22, 2025 | Giroux Richard | Open Market Sale | 24000 | 8.52 | $ 204,480.00 |
| Jul 8, 2025 | Forbes Alexandria | Open Market Sale | 47500 | 7.97 | $ 378,575.00 |
| Jun 30, 2025 | Giroux Richard | Other Disposition | 5000 | 0.00 | $ 0.00 |
| Jun 6, 2025 | Harris Keith R. | Option Excercise | 75000 | | $ 0.00 |
| Apr 22, 2025 | Giroux Richard | Open Market Sale | 24000 | 6.00 | $ 144,000.00 |
| Apr 8, 2025 | Forbes Alexandria | Open Market Sale | 47500 | 5.34 | $ 253,650.00 |
| Feb 21, 2025 | Forbes Alexandria | Option Excercise | 125000 | | $ 0.00 |
| Feb 21, 2025 | Forbes Alexandria | Option Excercise | 66095 | 7.30 | $ 482,493.50 |
| Feb 21, 2025 | Zeldin Robert K | Option Excercise | 15000 | | $ 0.00 |
| Feb 21, 2025 | Zeldin Robert K | Option Excercise | 5903 | 7.30 | $ 43,091.90 |
| Feb 21, 2025 | Wollin Robert J | Option Excercise | 22500 | | $ 0.00 |
| Feb 21, 2025 | Wollin Robert J | Option Excercise | 12116 | 7.30 | $ 88,446.80 |
| Feb 21, 2025 | Naylor Stuart | Option Excercise | 50000 | | $ 0.00 |
| Feb 21, 2025 | Naylor Stuart | Option Excercise | 23500 | 7.30 | $ 171,550.00 |
| Feb 21, 2025 | Giroux Richard | Option Excercise | 120000 | | $ 0.00 |
| Feb 21, 2025 | Giroux Richard | Option Excercise | 63452 | 7.30 | $ 463,199.60 |