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Top movers analysis in the middle of the day on 2025-08-21: top gainers and losers in today's session.

By Mill Chart

Last update: Aug 21, 2025

Let's have a look at what is happening on the US markets in the middle of the day on Thursday. Below you can find the top gainers and losers in today's session.


topmovers

Gainers

TickerChangeComment
PTIX102.0%Investors witnessed a remarkable 102.0% rise in PROTAGENIC THERAPEUTICS INC's (NASDAQ:PTIX) shares, which climbed to $4.6 during Thursday's session. In the last month the share price dropped with 32.34%.
AEMD54.95%AETHLON MEDICAL INC (NASDAQ:AEMD) experienced a significant 54.95% increase, reaching $1.72 during Thursday's session. The stock is trading 20.71% lower than a month ago.
SLQT38.52%Exciting news for SELECTQUOTE INC (NYSE:SLQT) as its stock price surged 38.52% to $2.54 during Thursday's session. The company's earnings where released Yesterday. A press release (INVESTOR ALERT: Pomerantz Law Firm Reminds Investors with Losses on their Investment in SelectQuote, Inc. of Class Action Lawsuit and Upcoming Deadlines - SLQT) was released earlier today.
THAR35.7%THARIMMUNE INC (NASDAQ:THAR) experienced a significant 35.7% increase, reaching $4.87 during Thursday's session. A press release (Tharimmune Reports Pharmacokinetic Simulation Results for TH104 as Prophylaxis Against Respiratory Depression from Fentanyl and Ultrapotent Opioids, Highlighting Potential Superiority Over Existing Treatments) was released yesterday.
CUPR28.57%Investors celebrated as CUPRINA HOLDINGS CAYMAN-A (NASDAQ:CUPR) experienced a 28.57% rise in its shares, closing at $1.08 during Thursday's session. In the last month the stock lost 89.16%.
IMRX26.67%IMMUNEERING CORP - CLASS A (NASDAQ:IMRX) experienced a significant 26.67% increase, reaching $4.34 during Thursday's session. In the last 3 months the share price increased with 123.0%.
FLYE25.62%FLY-E GROUP INC's (NASDAQ:FLYE) stock price is advancing with 25.62% to a price of $0.76. The stock is trading 88.45% lower than a month ago.
STSS22.24%SHARPS TECHNOLOGY INC's (NASDAQ:STSS) stock price displayed strong growth, advancing 22.24% and reaching $5.92 during Thursday's session. Shareholders saw the stock price going 23.17% lower in the past month.
APUS21.55%In an impressive move, APIMEDS PHARMACEUTICALS US I's (NYSEARCA:APUS) shares recorded a 21.55% increase, closing at $2.2 during Thursday's session.
STAK20.98%STAK INC-A's (NASDAQ:STAK) stock price increased by 20.98% to $1.73. In the last month the share price dropped with 24.74%.

To see the full list of top gainers you can use our top gainers page.

Losers

TickerChangeComment
MODV-62.87%MODIVCARE INC's (NASDAQ:MODV) shares fell 62.87% to $0.69. Yesterday the company had a press release: Modivcare Enters into Comprehensive Restructuring Agreement to Strengthen its Future, Reduce Debt and Inject Capital.
STFS-55.89%STAR FASHION CULTURE HLDG-A's (NASDAQ:STFS) stock price encountered a 55.89% decline, reaching $0.19 during Thursday's session. In the last month the stock lost 75.56%.
GWAV-46.53%GREENWAVE TECHNOLOGY SOLUTIO's (NASDAQ:GWAV) stock price decreased by 46.53% to $0.09. In the last month the share price dropped with 42.86%.
QH-37.61%QUHUO LTD-ADR's (NASDAQ:QH) stock price faced a 37.61% decline, reaching $0.06 during Thursday's session. In the last month the share price dropped with 93.6%.
SUGP-31.05%SU GROUP HOLDINGS LTD's (NASDAQ:SUGP) shares fell 31.05% to $0.4 during Thursday's session. In the last month the stock lost 22.72%.
RMSG-27.64%REAL MESSENGER CORP's (NASDAQ:RMSG) stock price decreased by 27.64% to $3.77. Shareholders saw the stock price going 126.0% higher in the past month.
ZYBT-26.12%ZHENGYE BIOTECHNOLOGY HOLDIN's (NASDAQ:ZYBT) stock price decreased by 26.12% to $7.01. In the last month the stock gained 64.19%.
DFLIW-22.37%The market experienced a downward movement in CHARDAN NEXTECH ACQUISI-CW27's (NASDAQ:DFLIW) stock price, closing at $0.04 with a 22.37% decrease during Thursday's session. The stock is trading 27.4% higher than a month ago.
NVNO-20.37%ENVVENO MEDICAL CORP's (NASDAQ:NVNO) stock price encountered a 20.37% decline, reaching $0.93 during Thursday's session. A press release (enVVeno Receives Not-Approvable Letter from the FDA for the VenoValve(R)) was released yesterday.
COTY-20.06%COTY INC-CL A's (NYSE:COTY) shares fell 20.06% to $3.88 during Thursday's session. A press release (Coty Reports FY25 and Q4 Results; Targets Sequential LFL and EBITDA Trend Improvement in FY26, Returning to Growth in 2H26) was released yesterday.

For the full top loser list go to our top losers page.

PROTAGENIC THERAPEUTICS INC

NASDAQ:PTIX (8/21/2025, 12:27:10 PM)

4.9396

+2.66 (+116.65%)


COTY INC-CL A

NYSE:COTY (8/21/2025, 12:27:08 PM)

3.83

-1.03 (-21.19%)


AETHLON MEDICAL INC

NASDAQ:AEMD (8/21/2025, 12:27:10 PM)

1.915

+0.81 (+72.52%)


SELECTQUOTE INC

NYSE:SLQT (8/21/2025, 12:27:04 PM)

2.509

+0.68 (+37.1%)


QUHUO LTD-ADR

NASDAQ:QH (8/21/2025, 12:26:30 PM)

0.0641

-0.04 (-38.19%)


MODIVCARE INC

NASDAQ:MODV (8/21/2025, 12:27:09 PM)

0.6584

-1.19 (-64.41%)


IMMUNEERING CORP - CLASS A

NASDAQ:IMRX (8/21/2025, 12:27:10 PM)

4.42

+0.99 (+28.86%)


ENVVENO MEDICAL CORP

NASDAQ:NVNO (8/21/2025, 12:27:00 PM)

0.9361

-0.23 (-19.99%)


SHARPS TECHNOLOGY INC

NASDAQ:STSS (8/21/2025, 12:27:05 PM)

5.95

+1.11 (+22.93%)


GREENWAVE TECHNOLOGY SOLUTIO

NASDAQ:GWAV (8/21/2025, 12:27:06 PM)

0.091

-0.08 (-46.47%)


CHARDAN NEXTECH ACQUISI-CW27

NASDAQ:DFLIW (8/21/2025, 12:26:32 PM)

0.0363

-0.01 (-21.94%)


THARIMMUNE INC

NASDAQ:THAR (8/21/2025, 12:27:06 PM)

4.75

+1.16 (+32.31%)


SU GROUP HOLDINGS LTD

NASDAQ:SUGP (8/21/2025, 12:26:21 PM)

0.395

-0.18 (-31.9%)


FLY-E GROUP INC

NASDAQ:FLYE (8/21/2025, 12:27:08 PM)

0.7652

+0.16 (+26.48%)


STAR FASHION CULTURE HLDG-A

NASDAQ:STFS (8/21/2025, 12:27:09 PM)

0.2

-0.24 (-54.55%)


REAL MESSENGER CORP

NASDAQ:RMSG (8/21/2025, 12:25:26 PM)

3.81

-1.4 (-26.87%)


ZHENGYE BIOTECHNOLOGY HOLDIN

NASDAQ:ZYBT (8/21/2025, 12:23:26 PM)

6.8

-2.69 (-28.35%)


STAK INC-A

NASDAQ:STAK (8/21/2025, 12:27:01 PM)

1.62

+0.19 (+13.29%)


CUPRINA HOLDINGS CAYMAN-A

NASDAQ:CUPR (8/21/2025, 12:27:02 PM)

1.069

+0.23 (+27.26%)


APIMEDS PHARMACEUTICALS US I

NYSEARCA:APUS (8/21/2025, 12:26:36 PM)

2.1843

+0.37 (+20.68%)



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