Tuesday's pre-market session: top gainers and losers

Last update: Sep 2, 2025

Let's have a look at what is happening on the US markets before the opening bell on Tuesday. Below you can find the top gainers and losers in today's pre-market session.

Pre-market gainers

Ticker	Change	Comment
CARM	145.0%	Exciting news for CARISMA THERAPEUTICS INC (NASDAQ:CARM) as their shares soared 145.0% to $0.53 during the pre-market session on Tuesday. In the last month the stock lost 30.98%.
HWH	68.06%	HWH INTERNATIONAL INC's (NASDAQ:HWH) shares rose 68.06% to $2.42 during Tuesday's pre-market session. The stock is trading 46.67% lower than a year ago.
GCTK	45.73%	The pre-market session on Tuesday saw a significant rise in GLUCOTRACK INC's (NASDAQ:GCTK) shares, climbing 45.73% to $6.15. In the last month the stock lost 32.26%.
UTHR	44.34%	UNITED THERAPEUTICS CORP's (NASDAQ:UTHR) shares rose 44.34% to $439.9. A press release (United Therapeutics Corporation Announces TETON-2 Pivotal Study of Tyvaso® Meets Primary Endpoint for the Treatment of Idiopathic Pulmonary Fibrosis) was released earlier today.
MLYS	42.05%	MINERALYS THERAPEUTICS INC (NASDAQ:MLYS) recorded a 42.05% increase in share price during the pre-market session, reaching $21.99 on Tuesday. In the last 6 months the share price increased with 69.37%.
MNKD	32.9%	MANNKIND CORP's (NASDAQ:MNKD) stock price is advancing with 32.9% to a price of $6.1. In the last month the share price increased with 22.4%.
SSKN	28.57%	During Tuesday's pre-market session, STRATA SKIN SCIENCES INC (NASDAQ:SSKN) experienced a 28.57% increase, with the stock price reaching $3.06. Today's pre-market session builds upon the previous day's success, as SSKN continues its upward trajectory following a 17.24% gain.
CYTK	27.37%	CYTOKINETICS INC's (NASDAQ:CYTK) shares rose 27.37% to $45.0 during Tuesday's pre-market session. The stock is trading 23.2% lower than 6 months ago.
HYMCL	20.0%	The pre-market session on Tuesday saw a significant rise in HYCROFT MINING HOLDING -CW25's (NASDAQ:HYMCL) shares, climbing 20.0% to $0.01. Shareholders saw the stock price going 40.0% lower is the past 6 months.
CRMLW	19.68%	Investors witnessed a remarkable surge in CRITICAL METALS CORP-28 (NASDAQ:CRMLW) during Tuesday's pre-market session, with the stock price rising 19.68% to $2.25. In the last month the share price increased with 29.66%.

For the full premarket gainers list go to our premarket gainers page.

Pre-market losers

Ticker	Change	Comment
STSS	-26.2%	Tuesday's pre-market session showed a 26.2% decrease in the stock price of SHARPS TECHNOLOGY INC (NASDAQ:STSS), reaching $10.0. Yesterday's -15.47% decline during the regular session set the stage for further downside, as STSS experienced an additional drop of 26.2% in today's pre-market session.
SITC	-25.9%	SITE CENTERS CORP's (NYSE:SITC) stock price recorded a 25.9% decrease, falling to $9.1. In the last year the share price dropped with 79.65%.
TECX	-24.39%	TECTONIC THERAPEUTIC INC's (NASDAQ:TECX) stock price recorded a 24.39% decrease, falling to $19.31. The stock is trading 23.2% higher than a month ago.
CELU	-18.78%	CELULARITY INC-A's (NASDAQ:CELU) stock price recorded a 18.78% decrease, falling to $3.2. In the last month the stock gained 26.28%.
YYAI	-18.38%	The stock price of CONNEXA SPORTS TECHNOLOGIES (NASDAQ:YYAI) is declining by 18.38%, reaching $2.62 during Tuesday's pre-market session. The struggles persist for YYAI as it recorded a -15.97% decline during the regular session yesterday, indicating that the challenging days are not yet over.
CNVS	-17.99%	During Tuesday's pre-market session, the shares of CINEVERSE CORP (NASDAQ:CNVS) declined by 17.99%, reaching $4.01. The stock is trading 39.71% higher than 3 months ago.
CGC	-16.67%	CANOPY GROWTH CORP's (NASDAQ:CGC) shares experienced a 16.67% decline, falling to $1.5 during Tuesday's pre-market session. Shareholders saw the stock price going 71.43% higher in the past month.
MOVE	-16.07%	MOVANO INC's (NASDAQ:MOVE) shares fell 16.07% to $0.9. Despite yesterday's 73.25% gain, MOVE experiences a 16.07% decline in today's pre-market session, indicating a shift in market sentiment.
IPDN	-14.95%	PROFESSIONAL DIVERSITY NETWO's (NASDAQ:IPDN) stock price decreased by 14.95% to $5.69. The current market conditions exhibit high volatility as IPDN retraces its steps after yesterday's 247.0% gain.
GVH	-14.65%	GLOBAVEND HOLDINGS LTD's (NASDAQ:GVH) stock price recorded a 14.65% decrease, falling to $5.07. After a strong performance yesterday with a 28.99% gain, GVH shows signs of retracement with a 14.65% decline in today's pre-market session.

For the full premarket loser list go to our premarket losers page.