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Get insights into the top gainers and losers of Monday's pre-market session.

By Mill Chart

Last update: Jul 21, 2025

As the US market prepares to open on Monday, let's get an early glimpse into the pre-market session and identify the stocks leading the pack in terms of gains and losses.


premarket

Today's pre-market gainers

TickerChangeComment
PMN93.14%PROMIS NEUROSCIENCES INC's (NASDAQ:PMN) stock price increased by 93.14% to $0.85. Earlier today the company had a press release: ProMIS Neurosciences Granted Fast Track Designation by U.S. FDA for PMN310 in the Treatment of Alzheimer’s Disease.
HSDT82.47%HELIUS MEDICAL TECHNOLOGIE-A's (NASDAQ:HSDT) stock price is advancing with 82.47% to a price of $16.24. A press release (Helius Announces Positive Outcome of the Portable Neuromodulation Stimulator PoNS® Stroke Registrational Program and Upcoming Submission to FDA Under Breakthrough Designation) was released earlier today.
GCTK69.12%During Monday's pre-market session, GLUCOTRACK INC (NASDAQ:GCTK) experienced a 69.12% increase, with the stock price reaching $9.86. Shareholders saw the stock price going 38.89% lower in the past 3 months.
APLMW43.54%Exciting news for APOLLOMICS INC-27 (NASDAQ:APLMW) as their shares soared 43.54% to $0.03 during the pre-market session on Monday. In the last 3 months the share price increased with 118.0%.
TNFA38.97%TNF PHARMACEUTICALS INC's (NASDAQ:TNFA) stock price is advancing with 38.97% to a price of $0.12. In the last month the share price dropped with 37.41%.
IXHL37.87%INCANNEX HEALTHCARE INC's (NASDAQ:IXHL) shares rose 37.87% to $0.84. This is a continuation of yesterday's gain of 64.82%.
AIRE36.05%During Monday's pre-market session, REALPHA TECH CORP (NASDAQ:AIRE) experienced a 36.05% increase, with the stock price reaching $0.26. This is a continuation of yesterday's gain of 22.58%.
OPEN25.79%The pre-market session on Monday saw a significant rise in OPENDOOR TECHNOLOGIES INC's (NASDAQ:OPEN) shares, climbing 25.79% to $2.83. Yesterday's gain of 36.36% continues in today's pre-market with 25.79%.
ATNF24.96%180 LIFE SCIENCES CORP's (NASDAQ:ATNF) shares surged 24.96% to reach $2.35 during the pre-market session on Monday. The stock is trading 114.0% higher than a month ago.
NCNA23.06%NUCANA PLC-ADR's (NASDAQ:NCNA) shares surged 23.06% to reach $0.06 during the pre-market session on Monday. Shareholders saw the stock price going 60.97% lower in the past month.

For the full premarket gainers list go to our premarket gainers page.

Today's pre-market losers

TickerChangeComment
XPON-18.35%EXPION360 INC's (NASDAQ:XPON) stock price is declining with 18.35% to a price of $1.29. After running up 51.92% in yesterday's session, XPON is pulling back pre-market.
HOLOW-15.75%GOLDEN PATH ACQ -CW28's (NASDAQ:HOLOW) stock price recorded a 15.75% decrease, falling to $0.16. Shareholders saw the stock price going 55.91% higher in the past month.
TELO-11.84%Today's pre-market session reveals a 11.84% decline in the stock price of TELOMIR PHARMACEUTICALS INC (NASDAQ:TELO), now priced at $2.01. After experiencing a 88.43% increase in yesterday's session, TELO is showing a reversal in today's pre-market session with a 11.84% decrease.
PET-11.65%Despite yesterday's decline, WAG! GROUP CO (NASDAQ:PET) experienced a further 11.65% decrease in share price during Monday's pre-market session, reaching $0.11. In the last 6 months the share price dropped with 50.14%.
RMR-11.45%The stock price of RMR GROUP INC/THE - A (NASDAQ:RMR) is experiencing a decline of 11.45%, reaching $15.46 in today's pre-market session on Monday. Shareholders saw the stock price going 31.37% lower is the past year.
BRKR-10.97%Investors observed a 10.97% decline in BRUKER CORP's (NASDAQ:BRKR) stock price, which now stands at $36.1 during Monday's pre-market session. Earlier today the company had a press release: Bruker Announces Second Quarter 2025 Preliminary Results, Plans to Hold Q2 Earnings Conference Call on August 4, 2025.
BULLW-10.9%Monday's pre-market session showed a 10.9% decrease in the stock price of WEBULL CORP-30 (NASDAQ:BULLW), reaching $6.5. Following yesterday's gain of 24.14%, BULLW experiences a 10.9% decrease in today's pre-market session, indicating a pullback from the previous session's performance.
SUGP-9.56%SU GROUP HOLDINGS LTD's (NASDAQ:SUGP) stock price recorded a 9.56% decrease, falling to $0.85. SUGP already had a hard day yesterday: closing -13.76% lower during the regular session.
SRPT-8.35%SAREPTA THERAPEUTICS INC's (NASDAQ:SRPT) stock price decreased by 8.35% to $12.9. The negative momentum continues as SRPT experienced a -35.94% decline during the regular session yesterday, indicating ongoing challenges. A press release (SAREPTA THERAPEUTICS, INC. (NASDAQ: SRPT) SHAREHOLDER ALERT Bernstein Liebhard LLP Reminds Sarepta Therapeutics, Inc. Investors of Upcoming Deadline) was released earlier today.
BULL-7.93%Monday's pre-market session showed a 7.93% decrease in the stock price of WEBULL CORP (NASDAQ:BULL), reaching $15.55. Prices are quite volatile now: this is a reversal from yesterday's 17.05% gain.

Our premarket losers page will show you the full list.

BRUKER CORP

NASDAQ:BRKR (7/25/2025, 8:00:01 PM)

Premarket: 41.7 -0.24 (-0.57%)

41.94

+1.49 (+3.68%)


OPENDOOR TECHNOLOGIES INC

NASDAQ:OPEN (7/25/2025, 8:14:58 PM)

Premarket: 2.56 +0.02 (+0.79%)

2.54

+0.12 (+4.96%)


SAREPTA THERAPEUTICS INC

NASDAQ:SRPT (7/25/2025, 8:26:43 PM)

Premarket: 11.65 -0.28 (-2.35%)

11.93

-0.95 (-7.38%)


WEBULL CORP

NASDAQ:BULL (7/25/2025, 8:00:01 PM)

Premarket: 16.3 +0.25 (+1.59%)

16.045

-0.04 (-0.28%)


RMR GROUP INC/THE - A

NASDAQ:RMR (7/25/2025, 8:22:59 PM)

After market: 16.89 0 (0%)

16.89

-0.02 (-0.12%)


NUCANA PLC-ADR

NASDAQ:NCNA (7/25/2025, 8:10:26 PM)

Premarket: 0.0628 +0 (+5.37%)

0.0596

+0.01 (+10.37%)


HELIUS MEDICAL TECHNOLOGIE-A

NASDAQ:HSDT (7/25/2025, 8:00:01 PM)

After market: 8.18 +0.03 (+0.37%)

8.15

-0.12 (-1.45%)


180 LIFE SCIENCES CORP

NASDAQ:ATNF (7/25/2025, 8:00:00 PM)

Premarket: 2.61 -0.39 (-13%)

3

+0.87 (+40.85%)


INCANNEX HEALTHCARE INC

NASDAQ:IXHL (7/25/2025, 8:00:02 PM)

Premarket: 1.22 +0.17 (+16.19%)

1.05

-0.58 (-35.58%)


GLUCOTRACK INC

NASDAQ:GCTK (7/25/2025, 8:00:00 PM)

Premarket: 7.22 -0.2 (-2.7%)

7.42

-0.24 (-3.13%)


EXPION360 INC

NASDAQ:XPON (7/25/2025, 8:00:01 PM)

Premarket: 1.46 +0.02 (+1.39%)

1.44

+0.02 (+1.41%)


PROMIS NEUROSCIENCES INC

NASDAQ:PMN (7/25/2025, 8:17:22 PM)

Premarket: 0.9354 -0.05 (-5.18%)

0.9865

+0.08 (+8.89%)


WAG! GROUP CO

NASDAQ:PET (7/25/2025, 8:16:23 PM)

Premarket: 0.119 -0.01 (-4.8%)

0.125

0 (-2.19%)


GOLDEN PATH ACQ -CW28

NASDAQ:HOLOW (7/25/2025, 8:00:01 PM)

0.1797

+0.02 (+12.31%)


APOLLOMICS INC-27

NASDAQ:APLMW (7/25/2025, 8:00:00 PM)

0.0349

+0 (+12.94%)


REALPHA TECH CORP

NASDAQ:AIRE (7/25/2025, 8:00:00 PM)

Premarket: 0.415 0 (-0.95%)

0.419

-0.03 (-7.46%)


SU GROUP HOLDINGS LTD

NASDAQ:SUGP (7/25/2025, 8:27:16 PM)

Premarket: 0.898 0 (-0.23%)

0.9001

-0.08 (-8.15%)


TELOMIR PHARMACEUTICALS INC

NASDAQ:TELO (7/25/2025, 8:00:00 PM)

Premarket: 2.1 -0.09 (-4.11%)

2.19

-0.1 (-4.37%)


TNF PHARMACEUTICALS INC

NASDAQ:TNFA (7/25/2025, 8:00:01 PM)

Premarket: 0.1174 +0 (+0.51%)

0.1168

-0.02 (-11.52%)


WEBULL CORP-30

NASDAQ:BULLW (7/25/2025, 8:00:01 PM)

6.6

+0.01 (+0.15%)



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