Get insights into the top gainers and losers of Monday's pre-market session.

Last update: Jul 21, 2025

As the US market prepares to open on Monday, let's get an early glimpse into the pre-market session and identify the stocks leading the pack in terms of gains and losses.

Today's pre-market gainers

Ticker	Change	Comment
PMN	93.14%	PROMIS NEUROSCIENCES INC's (NASDAQ:PMN) stock price increased by 93.14% to $0.85. Earlier today the company had a press release: ProMIS Neurosciences Granted Fast Track Designation by U.S. FDA for PMN310 in the Treatment of Alzheimer’s Disease.
HSDT	82.47%	HELIUS MEDICAL TECHNOLOGIE-A's (NASDAQ:HSDT) stock price is advancing with 82.47% to a price of $16.24. A press release (Helius Announces Positive Outcome of the Portable Neuromodulation Stimulator PoNS® Stroke Registrational Program and Upcoming Submission to FDA Under Breakthrough Designation) was released earlier today.
GCTK	69.12%	During Monday's pre-market session, GLUCOTRACK INC (NASDAQ:GCTK) experienced a 69.12% increase, with the stock price reaching $9.86. Shareholders saw the stock price going 38.89% lower in the past 3 months.
APLMW	43.54%	Exciting news for APOLLOMICS INC-27 (NASDAQ:APLMW) as their shares soared 43.54% to $0.03 during the pre-market session on Monday. In the last 3 months the share price increased with 118.0%.
TNFA	38.97%	TNF PHARMACEUTICALS INC's (NASDAQ:TNFA) stock price is advancing with 38.97% to a price of $0.12. In the last month the share price dropped with 37.41%.
IXHL	37.87%	INCANNEX HEALTHCARE INC's (NASDAQ:IXHL) shares rose 37.87% to $0.84. This is a continuation of yesterday's gain of 64.82%.
AIRE	36.05%	During Monday's pre-market session, REALPHA TECH CORP (NASDAQ:AIRE) experienced a 36.05% increase, with the stock price reaching $0.26. This is a continuation of yesterday's gain of 22.58%.
OPEN	25.79%	The pre-market session on Monday saw a significant rise in OPENDOOR TECHNOLOGIES INC's (NASDAQ:OPEN) shares, climbing 25.79% to $2.83. Yesterday's gain of 36.36% continues in today's pre-market with 25.79%.
ATNF	24.96%	180 LIFE SCIENCES CORP's (NASDAQ:ATNF) shares surged 24.96% to reach $2.35 during the pre-market session on Monday. The stock is trading 114.0% higher than a month ago.
NCNA	23.06%	NUCANA PLC-ADR's (NASDAQ:NCNA) shares surged 23.06% to reach $0.06 during the pre-market session on Monday. Shareholders saw the stock price going 60.97% lower in the past month.

For the full premarket gainers list go to our premarket gainers page.

Today's pre-market losers

Ticker	Change	Comment
XPON	-18.35%	EXPION360 INC's (NASDAQ:XPON) stock price is declining with 18.35% to a price of $1.29. After running up 51.92% in yesterday's session, XPON is pulling back pre-market.
HOLOW	-15.75%	GOLDEN PATH ACQ -CW28's (NASDAQ:HOLOW) stock price recorded a 15.75% decrease, falling to $0.16. Shareholders saw the stock price going 55.91% higher in the past month.
TELO	-11.84%	Today's pre-market session reveals a 11.84% decline in the stock price of TELOMIR PHARMACEUTICALS INC (NASDAQ:TELO), now priced at $2.01. After experiencing a 88.43% increase in yesterday's session, TELO is showing a reversal in today's pre-market session with a 11.84% decrease.
PET	-11.65%	Despite yesterday's decline, WAG! GROUP CO (NASDAQ:PET) experienced a further 11.65% decrease in share price during Monday's pre-market session, reaching $0.11. In the last 6 months the share price dropped with 50.14%.
RMR	-11.45%	The stock price of RMR GROUP INC/THE - A (NASDAQ:RMR) is experiencing a decline of 11.45%, reaching $15.46 in today's pre-market session on Monday. Shareholders saw the stock price going 31.37% lower is the past year.
BRKR	-10.97%	Investors observed a 10.97% decline in BRUKER CORP's (NASDAQ:BRKR) stock price, which now stands at $36.1 during Monday's pre-market session. Earlier today the company had a press release: Bruker Announces Second Quarter 2025 Preliminary Results, Plans to Hold Q2 Earnings Conference Call on August 4, 2025.
BULLW	-10.9%	Monday's pre-market session showed a 10.9% decrease in the stock price of WEBULL CORP-30 (NASDAQ:BULLW), reaching $6.5. Following yesterday's gain of 24.14%, BULLW experiences a 10.9% decrease in today's pre-market session, indicating a pullback from the previous session's performance.
SUGP	-9.56%	SU GROUP HOLDINGS LTD's (NASDAQ:SUGP) stock price recorded a 9.56% decrease, falling to $0.85. SUGP already had a hard day yesterday: closing -13.76% lower during the regular session.
SRPT	-8.35%	SAREPTA THERAPEUTICS INC's (NASDAQ:SRPT) stock price decreased by 8.35% to $12.9. The negative momentum continues as SRPT experienced a -35.94% decline during the regular session yesterday, indicating ongoing challenges. A press release (SAREPTA THERAPEUTICS, INC. (NASDAQ: SRPT) SHAREHOLDER ALERT Bernstein Liebhard LLP Reminds Sarepta Therapeutics, Inc. Investors of Upcoming Deadline) was released earlier today.
BULL	-7.93%	Monday's pre-market session showed a 7.93% decrease in the stock price of WEBULL CORP (NASDAQ:BULL), reaching $15.55. Prices are quite volatile now: this is a reversal from yesterday's 17.05% gain.

Our premarket losers page will show you the full list.