Get insights into the top gainers and losers of Monday's pre-market session.

By Mill Chart - Last update: Jul 21, 2025

As the US market prepares to open on Monday, let's get an early glimpse into the pre-market session and identify the stocks leading the pack in terms of gains and losses.


premarket

Today's pre-market gainers

TickerChangeComment
PMN93.14%PROMIS NEUROSCIENCES INC's (NASDAQ:PMN) stock price increased by 93.14% to $0.85. Earlier today the company had a press release: ProMIS Neurosciences Granted Fast Track Designation by U.S. FDA for PMN310 in the Treatment of Alzheimer’s Disease.
HSDT82.47%HELIUS MEDICAL TECHNOLOGIE-A's (NASDAQ:HSDT) stock price is advancing with 82.47% to a price of $16.24. A press release (Helius Announces Positive Outcome of the Portable Neuromodulation Stimulator PoNS® Stroke Registrational Program and Upcoming Submission to FDA Under Breakthrough Designation) was released earlier today.
GCTK69.12%During Monday's pre-market session, GLUCOTRACK INC (NASDAQ:GCTK) experienced a 69.12% increase, with the stock price reaching $9.86. Shareholders saw the stock price going 38.89% lower in the past 3 months.
APLMW43.54%Exciting news for APOLLOMICS INC-27 (NASDAQ:APLMW) as their shares soared 43.54% to $0.03 during the pre-market session on Monday. In the last 3 months the share price increased with 118.0%.
TNFA38.97%TNF PHARMACEUTICALS INC's (NASDAQ:TNFA) stock price is advancing with 38.97% to a price of $0.12. In the last month the share price dropped with 37.41%.
IXHL37.87%INCANNEX HEALTHCARE INC's (NASDAQ:IXHL) shares rose 37.87% to $0.84. This is a continuation of yesterday's gain of 64.82%.
AIRE36.05%During Monday's pre-market session, REALPHA TECH CORP (NASDAQ:AIRE) experienced a 36.05% increase, with the stock price reaching $0.26. This is a continuation of yesterday's gain of 22.58%.
OPEN25.79%The pre-market session on Monday saw a significant rise in OPENDOOR TECHNOLOGIES INC's (NASDAQ:OPEN) shares, climbing 25.79% to $2.83. Yesterday's gain of 36.36% continues in today's pre-market with 25.79%.
ATNF24.96%180 LIFE SCIENCES CORP's (NASDAQ:ATNF) shares surged 24.96% to reach $2.35 during the pre-market session on Monday. The stock is trading 114.0% higher than a month ago.
NCNA23.06%NUCANA PLC-ADR's (NASDAQ:NCNA) shares surged 23.06% to reach $0.06 during the pre-market session on Monday. Shareholders saw the stock price going 60.97% lower in the past month.

For the full premarket gainers list go to our premarket gainers page.

Today's pre-market losers

TickerChangeComment
XPON-18.35%EXPION360 INC's (NASDAQ:XPON) stock price is declining with 18.35% to a price of $1.29. After running up 51.92% in yesterday's session, XPON is pulling back pre-market.
HOLOW-15.75%GOLDEN PATH ACQ -CW28's (NASDAQ:HOLOW) stock price recorded a 15.75% decrease, falling to $0.16. Shareholders saw the stock price going 55.91% higher in the past month.
TELO-11.84%Today's pre-market session reveals a 11.84% decline in the stock price of TELOMIR PHARMACEUTICALS INC (NASDAQ:TELO), now priced at $2.01. After experiencing a 88.43% increase in yesterday's session, TELO is showing a reversal in today's pre-market session with a 11.84% decrease.
PET-11.65%Despite yesterday's decline, WAG! GROUP CO (NASDAQ:PET) experienced a further 11.65% decrease in share price during Monday's pre-market session, reaching $0.11. In the last 6 months the share price dropped with 50.14%.
RMR-11.45%The stock price of RMR GROUP INC/THE - A (NASDAQ:RMR) is experiencing a decline of 11.45%, reaching $15.46 in today's pre-market session on Monday. Shareholders saw the stock price going 31.37% lower is the past year.
BRKR-10.97%Investors observed a 10.97% decline in BRUKER CORP's (NASDAQ:BRKR) stock price, which now stands at $36.1 during Monday's pre-market session. Earlier today the company had a press release: Bruker Announces Second Quarter 2025 Preliminary Results, Plans to Hold Q2 Earnings Conference Call on August 4, 2025.
BULLW-10.9%Monday's pre-market session showed a 10.9% decrease in the stock price of WEBULL CORP-30 (NASDAQ:BULLW), reaching $6.5. Following yesterday's gain of 24.14%, BULLW experiences a 10.9% decrease in today's pre-market session, indicating a pullback from the previous session's performance.
SUGP-9.56%SU GROUP HOLDINGS LTD's (NASDAQ:SUGP) stock price recorded a 9.56% decrease, falling to $0.85. SUGP already had a hard day yesterday: closing -13.76% lower during the regular session.
SRPT-8.35%SAREPTA THERAPEUTICS INC's (NASDAQ:SRPT) stock price decreased by 8.35% to $12.9. The negative momentum continues as SRPT experienced a -35.94% decline during the regular session yesterday, indicating ongoing challenges. A press release (SAREPTA THERAPEUTICS, INC. (NASDAQ: SRPT) SHAREHOLDER ALERT Bernstein Liebhard LLP Reminds Sarepta Therapeutics, Inc. Investors of Upcoming Deadline) was released earlier today.
BULL-7.93%Monday's pre-market session showed a 7.93% decrease in the stock price of WEBULL CORP (NASDAQ:BULL), reaching $15.55. Prices are quite volatile now: this is a reversal from yesterday's 17.05% gain.

Our premarket losers page will show you the full list.

BRUKER CORP

NASDAQ:BRKR (2/27/2026, 8:00:02 PM)

After market: 40.11 0 (0%)

40.11

-0.91 (-2.22%)


OPENDOOR TECHNOLOGIES INC

NASDAQ:OPEN (2/27/2026, 8:25:30 PM)

After market: 5.38 -0.04 (-0.74%)

5.42

+0.01 (+0.18%)


SAREPTA THERAPEUTICS INC

NASDAQ:SRPT (2/27/2026, 8:00:00 PM)

After market: 16.71 -0.05 (-0.3%)

16.76

-0.69 (-3.95%)


WEBULL CORP

NASDAQ:BULL (2/27/2026, 8:00:02 PM)

After market: 5.8399 +0.03 (+0.51%)

5.81

-0.2 (-3.33%)


RMR GROUP INC/THE - A

NASDAQ:RMR (2/27/2026, 8:00:02 PM)

After market: 16.3605 -0.02 (-0.12%)

16.38

-0.23 (-1.38%)


NUCANA PLC-ADR

NASDAQ:NCNA (2/27/2026, 8:22:33 PM)

2.16

-0.03 (-1.37%)


SOLANA CO

NASDAQ:HSDT (2/27/2026, 8:08:56 PM)

After market: 1.87 0 (0%)

1.87

-0.24 (-11.37%)


180 LIFE SCIENCES CORP

NASDAQ:ATNF (8/15/2025, 8:06:05 PM)

After market: 7.29 +0.25 (+3.55%)

7.04

-0.57 (-7.49%)


INCANNEX HEALTHCARE INC

NASDAQ:IXHL (2/27/2026, 8:12:04 PM)

After market: 4.25 +0.01 (+0.24%)

4.24

-0.77 (-15.37%)


GLUCOTRACK INC

NASDAQ:GCTK (2/27/2026, 8:06:41 PM)

After market: 1.55 0 (0%)

1.55

-0.09 (-5.49%)


EXPION360 INC

NASDAQ:XPON (2/27/2026, 8:00:02 PM)

After market: 0.653 0 (-0.38%)

0.6555

-0.04 (-5.94%)


PROMIS NEUROSCIENCES INC

NASDAQ:PMN (2/27/2026, 8:27:13 PM)

After market: 23.89 +0.38 (+1.62%)

23.51

+2.65 (+12.7%)


WAG! GROUP CO

NASDAQ:PET (7/29/2025, 8:11:09 PM)

After market: 0.0489 +0 (+4.26%)

0.0469

-0.07 (-59.91%)


GOLDEN PATH ACQ -CW28

NASDAQ:HOLOW (2/27/2026, 8:08:48 PM)

After market: 0.09 0 (-0.11%)

0.0901

+0 (+0.11%)


APOLLOMICS INC-27

NASDAQ:APLMW (2/27/2026, 8:00:02 PM)

0.0119

0 (-7.75%)


REALPHA TECH CORP

NASDAQ:AIRE (2/27/2026, 8:00:00 PM)

After market: 0.3233 +0.01 (+1.7%)

0.3179

-0.02 (-5.81%)


SU GROUP HOLDINGS LTD

NASDAQ:SUGP (2/27/2026, 8:00:00 PM)

5.13

-0.08 (-1.54%)


TELOMIR PHARMACEUTICALS INC

NASDAQ:TELO (2/27/2026, 8:00:00 PM)

After market: 1.27 0 (0%)

1.27

-0.04 (-3.05%)


TNF PHARMACEUTICALS INC

NASDAQ:TNFA (9/24/2025, 8:00:01 PM)

After market: 4.4801 -0.72 (-13.84%)

5.2

+1.69 (+48.15%)


WEBULL CORP-30

NASDAQ:BULLW (2/27/2026, 8:00:02 PM)

1.7499

+0.05 (+2.94%)



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