| Sep 19, 2025 | Geiger Uri | Grant | 1194 | 9.94 | $ 11,868.36 |
| Sep 19, 2025 | LACOB JOSEPH | Grant | 1131 | 9.94 | $ 11,242.14 |
| Sep 19, 2025 | Kumar Rakhi | Grant | 1509 | 9.94 | $ 14,999.46 |
| Sep 19, 2025 | Fischer Frank M | Grant | 2389 | 9.94 | $ 23,746.66 |
| Sep 3, 2025 | Morrell Martha | Option Excercise | 1337 | 9.36 | $ 12,514.32 |
| Aug 27, 2025 | Becker Joel | Option Excercise | 1126 | 8.88 | $ 9,998.88 |
| Aug 27, 2025 | Morrell Martha | Option Excercise | 357 | 8.88 | $ 3,170.16 |
| Aug 20, 2025 | Morrell Martha | Option Excercise | 3052 | 8.66 | $ 26,430.32 |
| Jun 21, 2025 | Geiger Uri | Grant | 1140 | 10.41 | $ 11,867.40 |
| Jun 21, 2025 | Kumar Rakhi | Grant | 1440 | 10.41 | $ 14,990.40 |
| Jun 21, 2025 | LACOB JOSEPH | Grant | 1080 | 10.41 | $ 11,242.80 |
| Jun 21, 2025 | Fischer Frank M | Grant | 2281 | 10.41 | $ 23,745.21 |
| Jun 20, 2025 | Williams Patrick F. | Grant | 51850 | 0.00 | $ 0.00 |
| Jun 3, 2025 | Morrell Martha | Option Excercise | 1338 | 13.54 | $ 18,116.52 |
| Jun 3, 2025 | Kuhn Rebecca | Option Excercise | 1337 | 13.54 | $ 18,102.98 |
| May 27, 2025 | Becker Joel | Option Excercise | 1126 | 12.66 | $ 14,255.16 |
| May 27, 2025 | Kuhn Rebecca | Option Excercise | 357 | 12.66 | $ 4,519.62 |
| May 27, 2025 | Morrell Martha | Option Excercise | 357 | 12.66 | $ 4,519.62 |
| May 20, 2025 | Kuhn Rebecca | Option Excercise | 3051 | 17.99 | $ 54,887.49 |
| May 20, 2025 | Morrell Martha | Option Excercise | 3051 | 17.99 | $ 54,887.49 |
| May 14, 2025 | ORBIMED ADVISORS LLC | Open Market Sale | 168136 | 15.85 | $ 2,665,332.88 |
| May 14, 2025 | OrbiMed Capital GP VI LLC | Open Market Sale | 168136 | 15.85 | $ 2,665,332.88 |
| Apr 22, 2025 | Kuhn Rebecca | Option Excercise | 237 | 10.94 | $ 2,592.78 |
| Apr 22, 2025 | Morrell Martha | Option Excercise | 237 | 10.94 | $ 2,592.78 |
| Mar 24, 2025 | Morrell Martha | Grant | 11700 | 0.00 | $ 0.00 |
| Mar 3, 2025 | Morrell Martha | Option Excercise | 1337 | 11.81 | $ 15,789.97 |
| Mar 3, 2025 | Kuhn Rebecca | Option Excercise | 1337 | 11.81 | $ 15,789.97 |
| Feb 27, 2025 | Kuhn Rebecca | Option Excercise | 1430 | 12.56 | $ 17,960.80 |
| Feb 27, 2025 | Morrell Martha | Option Excercise | 1430 | 12.56 | $ 17,960.80 |
| Feb 21, 2025 | Morrell Martha | Open Market Sale | 78334 | 13.72 | $ 1,074,844.31 |
| Feb 20, 2025 | KCK LTD. | Open Market Sale | 5270845 | 9.40 | $ 49,545,943.00 |
| Feb 20, 2025 | Kuhn Rebecca | Option Excercise | 3405 | 14.23 | $ 48,453.15 |
| Feb 20, 2025 | Morrell Martha | Option Excercise | 3405 | 14.23 | $ 48,453.15 |
| Jan 29, 2025 | Morrell Martha | Open Market Sale | 300 | 15.00 | $ 4,500.00 |
| Jan 24, 2025 | Morrell Martha | Open Market Sale | 3200 | 15.01 | $ 48,032.00 |