| Dec 19, 2025 | Hopfner Robert Lorne | Open Market Purchase | 1000 | 17.35 | $ 17,350.00 |
| Dec 9, 2025 | Pena Luis C. | Option Excercise | 28138 | 17.84 | $ 501,981.92 |
| Dec 9, 2025 | Patel Jeegar Pravinkumar | Option Excercise | 7513 | 17.84 | $ 134,031.92 |
| Dec 9, 2025 | Moss Gregory S. | Option Excercise | 13624 | 17.84 | $ 243,052.16 |
| Dec 9, 2025 | Drew Janice Suzann | Option Excercise | 5074 | 17.84 | $ 90,520.16 |
| Dec 9, 2025 | Carver Kyle | Option Excercise | 13290 | 17.84 | $ 237,093.60 |
| Dec 9, 2025 | Bauer Eugene | Option Excercise | 1478 | 17.84 | $ 26,367.52 |
| Nov 7, 2025 | Cohen David E | Other Aquisition | 6056 | | $ 0.00 |
| Nov 7, 2025 | Carver Kyle | Other Aquisition | 3175 | | $ 0.00 |
| Nov 7, 2025 | Bauer Eugene | Other Aquisition | 25812 | | $ 0.00 |
| Nov 7, 2025 | RA CAPITAL MANAGEMENT, LLC | Other Aquisition | 2208770 | | $ 0.00 |
| Nov 7, 2025 | RA CAPITAL MANAGEMENT, LLC | Open Market Purchase | 1250000 | 16.00 | $ 20,000,000.00 |
| Nov 7, 2025 | Pivotal bioVenture Partners Fund I, L.P. | Other Aquisition | 3367975 | | $ 0.00 |
| Nov 7, 2025 | Pivotal bioVenture Partners Fund I G.P., L.P. | Other Aquisition | 3367975 | | $ 0.00 |
| Nov 7, 2025 | Pivotal bioVenture Partners Fund I U.G.P., Ltd | Other Aquisition | 3367975 | | $ 0.00 |
| Nov 7, 2025 | LSP 7 Cooperative UA | Other Aquisition | 3367133 | | $ 0.00 |
| Nov 7, 2025 | LSP 7 Cooperative UA | Open Market Purchase | 1562500 | 16.00 | $ 25,000,000.00 |
| Nov 7, 2025 | Verduyn-van Weegen Felice Isabel | Other Aquisition | 3367133 | | $ 0.00 |
| Nov 7, 2025 | Verduyn-van Weegen Felice Isabel | Open Market Purchase | 1562500 | 16.00 | $ 25,000,000.00 |
| Nov 7, 2025 | Pena Luis C. | Other Aquisition | 24225 | | $ 0.00 |
| Nov 7, 2025 | Patel Jeegar Pravinkumar | Other Aquisition | 3175 | | $ 0.00 |
| Nov 7, 2025 | Moss Gregory S. | Other Aquisition | 3175 | | $ 0.00 |
| Nov 7, 2025 | Hopfner Robert Lorne | Other Aquisition | 3371001 | | $ 0.00 |
| Nov 7, 2025 | Drew Janice Suzann | Other Aquisition | 1587 | | $ 0.00 |