| Jan 12, 2026 | Vida Ventures II, LLC | Open Market Purchase | 835000 | 18.00 | $ 15,030,000.00 |
| Jan 12, 2026 | VIDA VENTURES II-A, LLC | Open Market Purchase | 835000 | 18.00 | $ 15,030,000.00 |
| Jan 12, 2026 | EcoR1 Capital, LLC | Other Aquisition | 2602247 | | $ 0.00 |
| Jan 12, 2026 | NODELMAN OLEG | Other Aquisition | 2602247 | | $ 0.00 |
| Jan 12, 2026 | EcoR1 Capital, LLC | Open Market Purchase | 2222222 | 18.00 | $ 39,999,996.00 |
| Jan 12, 2026 | NODELMAN OLEG | Open Market Purchase | 2222222 | 18.00 | $ 39,999,996.00 |
| Jan 12, 2026 | Foley Todd | Other Aquisition | 4002533 | | $ 0.00 |
| Jan 12, 2026 | Foley Todd | Open Market Purchase | 232870 | 18.00 | $ 4,191,660.00 |
| Jan 12, 2026 | MPM BIOVENTURES 2018, L.P. | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | EVNIN LUKE | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM BIOVENTURES 2018 (B), L.P. | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM BioVentures 2018 LLC | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM BioVentures 2018 GP LLC | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM ASSET MANAGEMENT INVESTORS BV2018 LLC | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM ONCOLOGY INNOVATIONS FUND LP | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM Oncology Innovations Fund GP LLC | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM BIOVENTURES 2018, L.P. | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | EVNIN LUKE | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | MPM BIOVENTURES 2018 (B), L.P. | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | MPM BioVentures 2018 LLC | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | MPM BioVentures 2018 GP LLC | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | MPM ASSET MANAGEMENT INVESTORS BV2018 LLC | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | MPM ONCOLOGY INNOVATIONS FUND LP | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | MPM Oncology Innovations Fund GP LLC | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | GADICKE ANSBERT | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | MPM ASSET MANAGEMENT LLC | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | Oncology Impact Private Investment Fund 2, L.P. | Other Aquisition | 8805578 | | $ 0.00 |
| Jan 12, 2026 | Kim Helen Susan | Other Aquisition | 4994212 | | $ 0.00 |
| Jan 12, 2026 | GADICKE ANSBERT | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | Kim Helen Susan | Open Market Purchase | 835000 | 18.00 | $ 15,030,000.00 |
| Jan 12, 2026 | MPM ASSET MANAGEMENT LLC | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | Segal Lloyd Mitchell | Other Aquisition | 19631 | | $ 0.00 |
| Jan 12, 2026 | Oncology Impact Private Investment Fund 2, L.P. | Open Market Purchase | 1112777 | 18.00 | $ 20,029,986.00 |
| Jan 12, 2026 | Vida Ventures II, LLC | Other Aquisition | 4994212 | | $ 0.00 |
| Jan 12, 2026 | VIDA VENTURES II-A, LLC | Other Aquisition | 4994212 | | $ 0.00 |