Before the US market kicks off on Tuesday, let's examine the pre-market session and unveil the notable performers among the S&P500 top gainers and losers.

Gainers
| Ticker | Change | Comment |
|---|---|---|
| VRTX | 6.17% | Exciting news for VERTEX PHARMACEUTICALS INC (NASDAQ:VRTX) as their shares soared 6.17% to $489.31 during the pre-market session on Tuesday. A press release (Vertex Announces Positive Week 36 Interim Analysis Results for Primary and All Secondary Endpoints in the RAINIER Phase 3 Trial of Povetacicept in Adults With IgA Nephropathy) was released yesterday. |
| BG | 5.18% | BUNGE GLOBAL SA (NYSE:BG) experienced an impressive 5.18% increase in share price, reaching $124.94 during the pre-market session on Tuesday. A press release (Bunge Outlines Strategic Growth and Value Creation Plan at 2026 Investor Day) was released earlier today. |
| BXP | 3.85% | Pre-market trading on Tuesday showed positive momentum for BXP INC (NYSE:BXP), as the stock price advanced 3.85% to reach $54.5. In the last 3 months the stock lost 26.51%. |
| CRWD | 2.5% | During Tuesday's pre-market session, CROWDSTRIKE HOLDINGS INC - A (NASDAQ:CRWD) experienced a 2.5% increase, with the stock price reaching $445.0. Shareholders saw the stock price going 22.73% higher is the past year. |
| COIN | 2.36% | COINBASE GLOBAL INC -CLASS A's (NASDAQ:COIN) stock price increased by 2.36% to $204.5. Shareholders saw the stock price going 21.0% higher in the past month. |
| GLW | 2.05% | CORNING INC's (NYSE:GLW) shares rose 2.05% to $131.7 during Tuesday's pre-market session. In the last 3 months the share price increased with 46.12%. |
| DD | 2.03% | DUPONT DE NEMOURS INC (NYSE:DD) rose 2.03% to $46.16 during Tuesday's pre-market session. In the last 6 months the stock lost 41.47%. |
For the full premarket gainers list go to our premarket gainers page.
Today's pre-market losers
| Ticker | Change | Comment |
|---|---|---|
| OXY | -2.78% | OCCIDENTAL PETROLEUM CORP's (NYSE:OXY) stock price decreased by 2.78% to $53.49. In the last 3 months the share price increased with 33.97%. |
| CME | -2.69% | CME GROUP INC's (NASDAQ:CME) stock price decreased by 2.69% to $310.52. Shareholders saw the stock price going 21.65% higher is the past 6 months. |
| QCOM | -2.25% | QUALCOMM INC's (NASDAQ:QCOM) shares fell 2.25% to $135.0 during Tuesday's pre-market session. The stock is trading 22.54% lower than 3 months ago. |
| HPE | -2.06% | HEWLETT PACKARD ENTERPRISE's (NYSE:HPE) stock price is declining with 2.06% to a price of $21.36. Yesterday the company had a press release: HPE Reports Fiscal 2026 First Quarter Results. |
Our premarket losers page will show you the full list.