Let's have a look at the top gainers and losers in the middle of the day of today's session.

Last update: Jul 30, 2025

Wondering how the US markets performed in the middle of the day on Wednesday? Discover the movers and shakers of today's session in our comprehensive analysis.

Gainers

Ticker	Change	Comment
REPL	86.4%	Investors celebrated as REPLIMUNE GROUP INC (NASDAQ:REPL) experienced a 86.4% rise in its shares, closing at $6.99 during Wednesday's session. Shareholders saw the stock price going 59.63% lower in the past month.
BGLC	41.93%	BIONEXUS GENE LAB CORP's (NASDAQ:BGLC) stock price displayed strong growth, advancing 41.93% and reaching $6.33 during Wednesday's session. A press release (BioNexus Gene Lab Corp. and Fidelion Diagnostics Announce Landmark Alliance—Touted as a new “DeepSeek Moment” in Precision Oncology) was released earlier today.
OP	37.75%	OCEANPAL INC's (NASDAQ:OP) stock price increased by 37.75% to $0.19. In the last month the share price dropped with 92.37%.
TYGO	33.33%	TIGO ENERGY INC's (NASDAQ:TYGO) stock price is advancing with 33.33% to a price of $1.64. Yesterday the company had a press release: Tigo Energy Reports Second Quarter 2025 Financial Results.
SGD	30.87%	SAFE & GREEN DEVELOPMENT COR's (NASDAQ:SGD) shares rose 30.87% to $1.65. In the last month the stock gained 46.51%.
RCON	26.11%	RECON TECHNOLOGY LTD-CLASS A (NASDAQ:RCON) experienced a significant 26.11% increase, reaching $2.85 during Wednesday's session. Shareholders saw the stock price going 28.41% higher in the past 3 months.
WING	25.22%	Exciting news for WINGSTOP INC (NASDAQ:WING) as its stock price surged 25.22% to $363.5 during Wednesday's session. yesterday the company released their earnings. Yesterday the company had a press release: Five Free Wings in Any Flavor - Wingstop Drops Deal for National Chicken Wing Day (& Teases Next Flavor).
IMAB	23.53%	With a 23.53% surge, I-MAB-SPONSORED ADR's (NASDAQ:IMAB) stock price reached $2.1 during Wednesday's session, signaling positive momentum. The stock is trading 29.75% lower than a month ago.
BENFW	23.08%	Exciting news for BENEFICIENT CO GROUP -28 (NASDAQ:BENFW) as its stock price surged 23.08% to $0.01 during Wednesday's session. Shareholders saw the stock price going 22.62% lower is the past 6 months.
CVM	22.77%	CEL-SCI CORP (NYSEARCA:CVM) witnessed a notable 22.77% uptick in its shares, reaching $8.78 during Wednesday's session. Shareholders saw the stock price going 212.0% higher in the past month.

For the full top gainers list go to our top gainers page.

Losers

Ticker	Change	Comment
VYNE	-74.13%	There was a notable decline in VYNE THERAPEUTICS INC's (NASDAQ:VYNE) shares, as they dropped 74.13% to $0.37 during Wednesday's session. Shareholders saw the stock price going 38.72% lower is the past 6 months.
PTHL	-40.42%	PHETON HOLDINGS LTD-A's (NASDAQ:PTHL) stock price decreased by 40.42% to $0.98. In the last month the share price dropped with 91.03%.
HCTI	-28.4%	There was a notable decline in HEALTHCARE TRIANGLE INC's (NASDAQ:HCTI) shares, as they dropped 28.4% to $0.04 during Wednesday's session. A press release (Healthcare Triangle, Inc. Announces 1-for-249 Reverse Stock Split as Part of Nasdaq Compliance Plan) was released yesterday.
CRDF	-27.64%	The market experienced a 27.64% downturn in CARDIFF ONCOLOGY INC's (NASDAQ:CRDF) stock price, closing at $2.4 during Wednesday's session. CRDF is releasing earnings today. In the last year the stock gained 47.77%.
DFLI	-26.45%	DRAGONFLY ENERGY HOLDINGS CO's (NASDAQ:DFLI) stock price is declining with 26.45% to a price of $0.28. In the last month the stock gained 133.0%.
HWH	-26.02%	HWH INTERNATIONAL INC's (NASDAQ:HWH) stock price decreased by 26.02% to $1.45. In the last month the stock gained 54.33%.
SLRX	-24.97%	SALARIUS PHARMACEUTICALS INC's (NASDAQ:SLRX) stock price faced a 24.97% decline, reaching $0.75 during Wednesday's session. The stock is trading 44.87% higher than 3 months ago.
STAI	-24.87%	During Wednesday's session, SCANTECH AI SYSTEMS INC's (NASDAQ:STAI) shares took a tumble, falling 24.87% to $0.89. Yesterday the company had a press release: ScanTech AI Unlocks Potential $100M Market Opportunity Through TIPS Procurement Contract with Creeksource Consulting.
SISI	-24.3%	SHINECO INC's (NASDAQ:SISI) stock price faced a 24.3% decline, reaching $0.17 during Wednesday's session. In the last 3 months the stock lost 74.89%.
GLE	-21.82%	There was a downturn in GLOBAL ENGINE GROUP HOLDIN-A's (NASDAQ:GLE) shares, as they experienced a 21.82% decline, closing at $0.86 during Wednesday's session. In the last month the stock lost 28.1%.

For the full top loser list go to our top losers page.