Let's have a look at the top gainers and losers in the middle of the day of today's session.

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Wondering how the US markets performed in the middle of the day on Wednesday? Discover the movers and shakers of today's session in our comprehensive analysis.


topmovers

Gainers

TickerChangeComment
REPL86.4%Investors celebrated as REPLIMUNE GROUP INC (NASDAQ:REPL) experienced a 86.4% rise in its shares, closing at $6.99 during Wednesday's session. Shareholders saw the stock price going 59.63% lower in the past month.
BGLC41.93%BIONEXUS GENE LAB CORP's (NASDAQ:BGLC) stock price displayed strong growth, advancing 41.93% and reaching $6.33 during Wednesday's session. A press release (BioNexus Gene Lab Corp. and Fidelion Diagnostics Announce Landmark Alliance—Touted as a new “DeepSeek Moment” in Precision Oncology) was released earlier today.
OP37.75%OCEANPAL INC's (NASDAQ:OP) stock price increased by 37.75% to $0.19. In the last month the share price dropped with 92.37%.
TYGO33.33%TIGO ENERGY INC's (NASDAQ:TYGO) stock price is advancing with 33.33% to a price of $1.64. Yesterday the company had a press release: Tigo Energy Reports Second Quarter 2025 Financial Results.
SGD30.87%SAFE & GREEN DEVELOPMENT COR's (NASDAQ:SGD) shares rose 30.87% to $1.65. In the last month the stock gained 46.51%.
RCON26.11%RECON TECHNOLOGY LTD-CLASS A (NASDAQ:RCON) experienced a significant 26.11% increase, reaching $2.85 during Wednesday's session. Shareholders saw the stock price going 28.41% higher in the past 3 months.
WING25.22%Exciting news for WINGSTOP INC (NASDAQ:WING) as its stock price surged 25.22% to $363.5 during Wednesday's session. yesterday the company released their earnings. Yesterday the company had a press release: Five Free Wings in Any Flavor - Wingstop Drops Deal for National Chicken Wing Day (& Teases Next Flavor).
IMAB23.53%With a 23.53% surge, I-MAB-SPONSORED ADR's (NASDAQ:IMAB) stock price reached $2.1 during Wednesday's session, signaling positive momentum. The stock is trading 29.75% lower than a month ago.
BENFW23.08%Exciting news for BENEFICIENT CO GROUP -28 (NASDAQ:BENFW) as its stock price surged 23.08% to $0.01 during Wednesday's session. Shareholders saw the stock price going 22.62% lower is the past 6 months.
CVM22.77%CEL-SCI CORP (NYSEARCA:CVM) witnessed a notable 22.77% uptick in its shares, reaching $8.78 during Wednesday's session. Shareholders saw the stock price going 212.0% higher in the past month.

For the full top gainers list go to our top gainers page.

Losers

TickerChangeComment
VYNE-74.13%There was a notable decline in VYNE THERAPEUTICS INC's (NASDAQ:VYNE) shares, as they dropped 74.13% to $0.37 during Wednesday's session. Shareholders saw the stock price going 38.72% lower is the past 6 months.
PTHL-40.42%PHETON HOLDINGS LTD-A's (NASDAQ:PTHL) stock price decreased by 40.42% to $0.98. In the last month the share price dropped with 91.03%.
HCTI-28.4%There was a notable decline in HEALTHCARE TRIANGLE INC's (NASDAQ:HCTI) shares, as they dropped 28.4% to $0.04 during Wednesday's session. A press release (Healthcare Triangle, Inc. Announces 1-for-249 Reverse Stock Split as Part of Nasdaq Compliance Plan) was released yesterday.
CRDF-27.64%The market experienced a 27.64% downturn in CARDIFF ONCOLOGY INC's (NASDAQ:CRDF) stock price, closing at $2.4 during Wednesday's session. CRDF is releasing earnings today. In the last year the stock gained 47.77%.
DFLI-26.45%DRAGONFLY ENERGY HOLDINGS CO's (NASDAQ:DFLI) stock price is declining with 26.45% to a price of $0.28. In the last month the stock gained 133.0%.
HWH-26.02%HWH INTERNATIONAL INC's (NASDAQ:HWH) stock price decreased by 26.02% to $1.45. In the last month the stock gained 54.33%.
SLRX-24.97%SALARIUS PHARMACEUTICALS INC's (NASDAQ:SLRX) stock price faced a 24.97% decline, reaching $0.75 during Wednesday's session. The stock is trading 44.87% higher than 3 months ago.
STAI-24.87%During Wednesday's session, SCANTECH AI SYSTEMS INC's (NASDAQ:STAI) shares took a tumble, falling 24.87% to $0.89. Yesterday the company had a press release: ScanTech AI Unlocks Potential $100M Market Opportunity Through TIPS Procurement Contract with Creeksource Consulting.
SISI-24.3%SHINECO INC's (NASDAQ:SISI) stock price faced a 24.3% decline, reaching $0.17 during Wednesday's session. In the last 3 months the stock lost 74.89%.
GLE-21.82%There was a downturn in GLOBAL ENGINE GROUP HOLDIN-A's (NASDAQ:GLE) shares, as they experienced a 21.82% decline, closing at $0.86 during Wednesday's session. In the last month the stock lost 28.1%.

For the full top loser list go to our top losers page.