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ANNEXON INC (ANNX) Stock Fundamental Analysis

USA - Nasdaq - NASDAQ:ANNX - US03589W1027 - Common Stock

4.97 USD
-0.07 (-1.39%)
Last: 12/12/2025, 8:14:03 PM
5.06 USD
+0.09 (+1.81%)
After Hours: 12/12/2025, 8:14:03 PM
Fundamental Rating

2

ANNX gets a fundamental rating of 2 out of 10. The analysis compared the fundamentals against 531 industry peers in the Biotechnology industry. While ANNX has a great health rating, there are worries on its profitability. ANNX does not seem to be growing, but still is valued expensively.


Dividend Valuation Growth Profitability Health

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0

1. Profitability

1.1 Basic Checks

ANNX had negative earnings in the past year.
In the past year ANNX has reported a negative cash flow from operations.
ANNX had negative earnings in each of the past 5 years.
ANNX had a negative operating cash flow in each of the past 5 years.
ANNX Yearly Net Income VS EBIT VS OCF VS FCFANNX Yearly Net Income VS EBIT VS OCF VS FCFYearly Net Income VS EBIT VS OCF VS FCF 2017 2018 2019 2020 2021 2022 2023 2024 -50M -100M -150M

1.2 Ratios

The Return On Assets of ANNX (-91.34%) is worse than 73.26% of its industry peers.
ANNX has a worse Return On Equity (-129.64%) than 62.34% of its industry peers.
Industry RankSector Rank
ROA -91.34%
ROE -129.64%
ROIC N/A
ROA(3y)-44.79%
ROA(5y)-39.91%
ROE(3y)-54.04%
ROE(5y)-47.75%
ROIC(3y)N/A
ROIC(5y)N/A
ANNX Yearly ROA, ROE, ROICANNX Yearly ROA, ROE, ROICYearly ROA, ROE, ROIC 2017 2018 2019 2020 2021 2022 2023 2024 -200 -400 -600

1.3 Margins

ANNX does not have Profit Margin and Operating Margin and Gross Margin available, so we won't be analyzing them here.
Industry RankSector Rank
OM N/A
PM (TTM) N/A
GM N/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
ANNX Yearly Profit, Operating, Gross MarginsANNX Yearly Profit, Operating, Gross MarginsYearly Profit, Operating, Gross Margins 2017 2018 2019 2020 2021 2022 2023 2024

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2. Health

2.1 Basic Checks

The number of shares outstanding for ANNX has been increased compared to 1 year ago.
ANNX has less shares outstanding than it did 5 years ago.
There is no outstanding debt for ANNX. This means it has a Debt/Equity and Debt/FCF ratio of 0 and it is amongst the best of the sector and industry.
ANNX Yearly Shares OutstandingANNX Yearly Shares OutstandingYearly Shares Outstanding 2017 2018 2019 2020 2021 2022 2023 2024 50M 100M 150M
ANNX Yearly Total Debt VS Total AssetsANNX Yearly Total Debt VS Total AssetsYearly Total Debt VS Total Assets 2017 2018 2019 2020 2021 2022 2023 2024 100M 200M 300M

2.2 Solvency

Based on the Altman-Z score of -1.21, we must say that ANNX is in the distress zone and has some risk of bankruptcy.
Looking at the Altman-Z score, with a value of -1.21, ANNX is in line with its industry, outperforming 53.30% of the companies in the same industry.
ANNX has no outstanding debt. Therefor its Debt/Equity and Debt/FCF ratios are 0 and belong to the best of the industry.
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Altman-Z -1.21
ROIC/WACCN/A
WACCN/A
ANNX Yearly LT Debt VS Equity VS FCFANNX Yearly LT Debt VS Equity VS FCFYearly LT Debt VS Equity VS FCF 2017 2018 2019 2020 2021 2022 2023 2024 0 100M -100M 200M 300M

2.3 Liquidity

ANNX has a Current Ratio of 4.42. This indicates that ANNX is financially healthy and has no problem in meeting its short term obligations.
Looking at the Current ratio, with a value of 4.42, ANNX is in line with its industry, outperforming 50.47% of the companies in the same industry.
A Quick Ratio of 4.42 indicates that ANNX has no problem at all paying its short term obligations.
ANNX has a Quick ratio of 4.42. This is comparable to the rest of the industry: ANNX outperforms 51.98% of its industry peers.
Industry RankSector Rank
Current Ratio 4.42
Quick Ratio 4.42
ANNX Yearly Current Assets VS Current LiabilitesANNX Yearly Current Assets VS Current LiabilitesYearly Current Assets VS Current Liabilites 2017 2018 2019 2020 2021 2022 2023 2024 100M 200M 300M

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3. Growth

3.1 Past

ANNX shows a strong negative growth in Earnings Per Share. In the last year the EPS decreased by -34.29%.
EPS 1Y (TTM)-34.29%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-48%
Revenue 1Y (TTM)N/A
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%N/A

3.2 Future

ANNX is expected to show a strong growth in Earnings Per Share. In the coming years, the EPS will grow by 28.91% yearly.
No Revenue estimates are available, so we could not analyze the future revenue growth and evolution.
EPS Next Y-39.58%
EPS Next 2Y-4.96%
EPS Next 3Y7.56%
EPS Next 5Y28.91%
Revenue Next YearN/A
Revenue Next 2YN/A
Revenue Next 3YN/A
Revenue Next 5YN/A

3.3 Evolution

No Revenue estimates are available, so we could not analyze the future revenue growth and evolution.
ANNX Yearly Revenue VS EstimatesANNX Yearly Revenue VS EstimatesYearly Revenue VS Estimates 2026 2027 2028 2029 2030 2031 2032 500M 1B
ANNX Yearly EPS VS EstimatesANNX Yearly EPS VS EstimatesYearly EPS VS Estimates 2020 2021 2022 2023 2024 2025 2026 2027 2028 2029 2030 2031 2032 0 2 -2

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4. Valuation

4.1 Price/Earnings Ratio

ANNX reported negative earnings for the last year, which makes the Price/Earnings Ratio negative.
Besides the negative Price/Earnings Ratio, also the Forward Price/Earnings Ratio is negative for ANNX. No positive earnings are expected for the next year.
Industry RankSector Rank
PE N/A
Fwd PE N/A
ANNX Price Earnings VS Forward Price EarningsANNX Price Earnings VS Forward Price Earnings ChartPrice Earnings - Forward Price Earnings PE FPE 0 20 40 60

4.2 Price Multiples

Industry RankSector Rank
P/FCF N/A
EV/EBITDA N/A
ANNX Per share dataANNX EPS, Sales, OCF, FCF, BookValue per sharePer Share Data Per Share 0 0.5 -0.5 1 -1

4.3 Compensation for Growth

PEG (NY)N/A
PEG (5Y)N/A
EPS Next 2Y-4.96%
EPS Next 3Y7.56%

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5. Dividend

5.1 Amount

No dividends for ANNX!.
Industry RankSector Rank
Dividend Yield N/A

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ANNEXON INC

NASDAQ:ANNX (12/12/2025, 8:14:03 PM)

After market: 5.06 +0.09 (+1.81%)

4.97

-0.07 (-1.39%)

Chartmill FA Rating
GICS SectorHealth Care
GICS IndustryGroupPharmaceuticals, Biotechnology & Life Sciences
GICS IndustryBiotechnology
Earnings (Last)11-10 2025-11-10/amc
Earnings (Next)03-02 2026-03-02/amc
Inst Owners72.32%
Inst Owner Change1.1%
Ins Owners0.44%
Ins Owner Change3.19%
Market Cap718.41M
Revenue(TTM)N/A
Net Income(TTM)-209.29M
Analysts84.29
Price Target14.79 (197.59%)
Short Float %6.4%
Short Ratio3.44
Dividend
Industry RankSector Rank
Dividend Yield N/A
Yearly DividendN/A
Dividend Growth(5Y)N/A
DPN/A
Div Incr Years0
Div Non Decr Years0
Ex-DateN/A
Surprises & Revisions
EPS beat(2)1
Avg EPS beat(2)1.08%
Min EPS beat(2)-6.69%
Max EPS beat(2)8.85%
EPS beat(4)1
Avg EPS beat(4)-10.1%
Min EPS beat(4)-22.39%
Max EPS beat(4)8.85%
EPS beat(8)5
Avg EPS beat(8)3.12%
EPS beat(12)9
Avg EPS beat(12)5.76%
EPS beat(16)11
Avg EPS beat(16)7.34%
Revenue beat(2)N/A
Avg Revenue beat(2)N/A
Min Revenue beat(2)N/A
Max Revenue beat(2)N/A
Revenue beat(4)N/A
Avg Revenue beat(4)N/A
Min Revenue beat(4)N/A
Max Revenue beat(4)N/A
Revenue beat(8)N/A
Avg Revenue beat(8)N/A
Revenue beat(12)N/A
Avg Revenue beat(12)N/A
Revenue beat(16)N/A
Avg Revenue beat(16)N/A
PT rev (1m)25%
PT rev (3m)25%
EPS NQ rev (1m)4.49%
EPS NQ rev (3m)4.49%
EPS NY rev (1m)-1.71%
EPS NY rev (3m)-0.68%
Revenue NQ rev (1m)N/A
Revenue NQ rev (3m)N/A
Revenue NY rev (1m)N/A
Revenue NY rev (3m)N/A
Valuation
Industry RankSector Rank
PE N/A
Fwd PE N/A
P/S N/A
P/FCF N/A
P/OCF N/A
P/B 4.45
P/tB 4.45
EV/EBITDA N/A
EPS(TTM)-1.41
EYN/A
EPS(NY)-1.12
Fwd EYN/A
FCF(TTM)-1.22
FCFYN/A
OCF(TTM)-1.22
OCFYN/A
SpS0
BVpS1.12
TBVpS1.12
PEG (NY)N/A
PEG (5Y)N/A
Graham NumberN/A
Profitability
Industry RankSector Rank
ROA -91.34%
ROE -129.64%
ROCE N/A
ROIC N/A
ROICexc N/A
ROICexgc N/A
OM N/A
PM (TTM) N/A
GM N/A
FCFM N/A
ROA(3y)-44.79%
ROA(5y)-39.91%
ROE(3y)-54.04%
ROE(5y)-47.75%
ROIC(3y)N/A
ROIC(5y)N/A
ROICexc(3y)N/A
ROICexc(5y)N/A
ROICexgc(3y)N/A
ROICexgc(5y)N/A
ROCE(3y)N/A
ROCE(5y)N/A
ROICexgc growth 3YN/A
ROICexgc growth 5YN/A
ROICexc growth 3YN/A
ROICexc growth 5YN/A
OM growth 3YN/A
OM growth 5YN/A
PM growth 3YN/A
PM growth 5YN/A
GM growth 3YN/A
GM growth 5YN/A
F-Score4
Asset Turnover0
Health
Industry RankSector Rank
Debt/Equity 0
Debt/FCF N/A
Debt/EBITDA N/A
Cap/Depr 6.8%
Cap/Sales N/A
Interest Coverage N/A
Cash Conversion N/A
Profit Quality N/A
Current Ratio 4.42
Quick Ratio 4.42
Altman-Z -1.21
F-Score4
WACCN/A
ROIC/WACCN/A
Cap/Depr(3y)106.39%
Cap/Depr(5y)92.98%
Cap/Sales(3y)N/A
Cap/Sales(5y)N/A
Profit Quality(3y)N/A
Profit Quality(5y)N/A
High Growth Momentum
Growth
EPS 1Y (TTM)-34.29%
EPS 3YN/A
EPS 5YN/A
EPS Q2Q%-48%
EPS Next Y-39.58%
EPS Next 2Y-4.96%
EPS Next 3Y7.56%
EPS Next 5Y28.91%
Revenue 1Y (TTM)N/A
Revenue growth 3YN/A
Revenue growth 5YN/A
Sales Q2Q%N/A
Revenue Next YearN/A
Revenue Next 2YN/A
Revenue Next 3YN/A
Revenue Next 5YN/A
EBIT growth 1Y-65.79%
EBIT growth 3YN/A
EBIT growth 5YN/A
EBIT Next Year-55.67%
EBIT Next 3Y-23.78%
EBIT Next 5YN/A
FCF growth 1Y-40.93%
FCF growth 3YN/A
FCF growth 5YN/A
OCF growth 1Y-41.36%
OCF growth 3YN/A
OCF growth 5YN/A

ANNEXON INC / ANNX FAQ

What is the fundamental rating for ANNX stock?

ChartMill assigns a fundamental rating of 2 / 10 to ANNX.


Can you provide the valuation status for ANNEXON INC?

ChartMill assigns a valuation rating of 0 / 10 to ANNEXON INC (ANNX). This can be considered as Overvalued.


Can you provide the profitability details for ANNEXON INC?

ANNEXON INC (ANNX) has a profitability rating of 0 / 10.


What is the financial health of ANNEXON INC (ANNX) stock?

The financial health rating of ANNEXON INC (ANNX) is 7 / 10.


What is the earnings growth outlook for ANNEXON INC?

The Earnings per Share (EPS) of ANNEXON INC (ANNX) is expected to decline by -39.58% in the next year.