ALPHA TEKNOVA INC (NASDAQ:TKNO) Reports Q4 2025 Results, Beats Revenue Estimates and Improves Margins

By Mill Chart - Last update: Feb 27, 2026

Article Mentions:

ALPHA TEKNOVA INC (NASDAQ:TKNO) reported its fourth quarter and full-year 2025 financial results after the market closed on Wednesday, delivering a top-line performance that narrowly exceeded analyst expectations while showing continued progress on its path toward profitability. The critical reagents manufacturer posted quarterly revenue of $10.0 million, an 8% increase over the prior year period.

Earnings Versus Estimates

The company's performance against Wall Street's forecasts presents a mixed but generally positive picture. Teknova's revenue for the quarter came in slightly above the consensus estimate, while its loss per share was marginally better than anticipated.

  • Q4 2025 Revenue: $10.0 million reported vs. $9.91 million estimated.
  • Q4 2025 EPS (Non-GAAP): -$0.09 reported vs. -$0.094 estimated.

For the full year 2025, total revenue reached $40.5 million, marking a 7% year-over-year increase and landing within the company's previously provided guidance range. This growth was achieved despite a challenging funding environment for the broader biotech sector, which the company serves.

Market Reaction and Price Action

The immediate market reaction to the earnings release appears muted in after-hours trading. However, the stock's performance in the lead-up to the report provides some context. Shares have experienced volatility over the past month but showed modest gains in the very short term preceding the earnings announcement.

  • After-Market Performance: Flat (0.0%) following the release.
  • Recent Performance: The stock gained approximately 9% over the past week, potentially indicating some investor optimism heading into the earnings report.

This subdued after-hours reaction suggests the results, while meeting or slightly beating expectations, may not have contained significant positive surprises to drive a sharp revaluation. Investors are likely focusing on the company's forward guidance and its ongoing cash burn.

Key Highlights from the Press Release

Beyond the headline numbers, management emphasized operational improvements and strategic positioning. The most significant developments include a dramatic improvement in gross margin and a substantial reduction in cash consumption.

  • Gross Margin Expansion: Full-year gross margin improved to 33.2%, up from 19.2% in 2024. This was driven largely by the absence of major inventory-related charges that impacted the prior year, as well as manufacturing efficiency gains.
  • Improved Cash Flow: The company significantly reduced its cash usage. Free Cash Flow for the full year was negative $9.8 million, a notable improvement from negative $13.5 million in 2024. Cash used in operating activities fell to $8.6 million from $12.4 million.
  • Clinical Solutions Growth: The higher-margin Clinical Solutions segment showed strong momentum, with revenue growing 47% year-over-year in the fourth quarter. The company also reported a 25% annual increase in Clinical Solutions customers.
  • Balance Sheet: The company ended the year with $21.3 million in total cash and short-term investments against $13.2 million in gross debt.

Forward Outlook and Analyst Comparisons

Teknova provided revenue guidance for the 2026 fiscal year in the range of $42 million to $44 million. This outlook implies a growth rate of approximately 4% to 9% over 2025.

  • Company's 2026 Revenue Guidance: $42 - $44 million.
  • Analyst Consensus for 2026 Sales: Approximately $45.0 million.

The company's guidance range sits slightly below the current analyst consensus, which may contribute to the cautious market reaction. Furthermore, management anticipates a full-year Free Cash Outflow of less than $10 million for 2026, indicating a continued but managed burn rate as it invests in commercial capabilities. CEO Stephen Gunstream stated the company believes "targeted commercial efforts should enable us to become Adjusted EBITDA positive by the end of 2027."

Conclusion

Teknova's fourth-quarter results reflect a company executing on its plan to improve operational efficiency and stem cash outflows while growing its core business. Beating modest revenue and earnings estimates is a positive step, but the market's tempered response likely stems from guidance that is cautious relative to analyst expectations and the ongoing reality of net losses. The substantial improvement in gross margin and the reduced cash burn are clear bright spots that underscore management's focus on financial discipline. The key question for investors remains the timeline to sustained profitability and the company's ability to accelerate top-line growth to meet longer-term targets.

For a detailed look at upcoming earnings estimates and historical performance, you can review the data here.

Disclaimer: This article is for informational purposes only and does not constitute financial advice, nor does it recommend buying or selling any securities. Investors should conduct their own research and consult with a qualified financial advisor before making any investment decisions.

ALPHA TEKNOVA INC

NASDAQ:TKNO (2/26/2026, 4:30:00 PM)

After market: 2.28 0 (0%)

2.28

+0.02 (+0.88%)



Find more stocks in the Stock Screener

Follow ChartMill for more
Follow us on StockTwitsFollow us on InstagramFollow us on FacebookFollow us on YouTube