The US market is yet to commence its session on Tuesday, but let's get a preview of the pre-market session and explore the top gainers and losers driving the early market movements.

Pre-market gainers
| Ticker | Change | Comment |
|---|---|---|
| APLS | 139.0% | APELLIS PHARMACEUTICALS INC's (NASDAQ:APLS) shares rose 139.0% to $40.8 during Tuesday's pre-market session. A press release (APLS Stock Alert: Halper Sadeh LLC is Investigating Whether Apellis Pharmaceuticals, Inc. is Obtaining a Fair Price for its Shareholders) was released earlier today. |
| HKIT | 128.0% | HITEK GLOBAL INC-CL A (NASDAQ:HKIT) rose 128.0% to $0.09 during Tuesday's pre-market session. After experiencing a -27.27% loss in the previous session, HKIT is showing resilience and signs of recovery in today's pre-market session. |
| VRAX | 83.32% | VIRAX BIOLABS GROUP LTD's (NASDAQ:VRAX) shares rose 83.32% to $0.3 during Tuesday's pre-market session. The stock is trading 26.24% lower than a month ago. |
| KIDZ | 53.17% | Exciting news for CLASSOVER HOLDINGS INC-CL B (NASDAQ:KIDZ) as their shares soared 53.17% to $3.14 during the pre-market session on Tuesday. Following yesterday's -17.34% decline, KIDZ shows promising signs of a rebound in today's pre-market session, indicating a potential recovery. Earlier today the company had a press release: Classover Regains Compliance with Nasdaq Minimum Bid Price Requirement. |
| CNTA | 46.74% | During Tuesday's pre-market session, CENTESSA PHARMACEUTICALS-ADR (NASDAQ:CNTA) experienced a 46.74% increase, with the stock price reaching $40.47. A press release (CNTA Stock Alert: Halper Sadeh LLC is Investigating Whether Centessa Pharmaceuticals plc is Obtaining a Fair Price for its Shareholders) was released earlier today. |
| MASK | 29.84% | 3 E NETWORK TECHNOLOGY GRP-A's (NASDAQ:MASK) shares rose 29.84% to $1.61 during Tuesday's pre-market session. The stock is trading 64.72% lower than a month ago. |
| LTRN | 21.86% | During Tuesday's pre-market session, LANTERN PHARMA INC (NASDAQ:LTRN) exhibited strong growth, with the stock price climbing 21.86% to $1.5. Also in the previous session LTRN had a very good day: shares closed with a 10.27% gain. Yesterday the company had a press release: Lantern Pharma Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Updates. |
| MGN | 19.39% | MEGAN HOLDINGS LTD-CL A (NASDAQ:MGN) recorded a 19.39% increase in share price during the pre-market session, reaching $0.17 on Tuesday. Only yesterday these shares were declining by -16.29%, so we see a bit of recovery today. |
| BFRG | 19.05% | During Tuesday's pre-market session, BULLFROG AI HOLDINGS INC (NASDAQ:BFRG) experienced a 19.05% increase, with the stock price reaching $1.25. Also in the previous session BFRG had a very good day: shares closed with a 107.0% gain. |
| ANNAW | 19.05% | ALEANNA INC - CL A - 29's (NASDAQ:ANNAW) shares rose 19.05% to $1.25. The positive momentum from yesterday's 34.24% gain carries forward into today's pre-market session, with an additional 19.05% increase. A press release (AleAnna, Inc. Reports Fourth Quarter and Full Year 2025 Results) was released yesterday. |
For the full premarket gainers list go to our premarket gainers page.
Today's pre-market losers
| Ticker | Change | Comment |
|---|---|---|
| PEPG | -49.89% | PEPGEN INC's (NASDAQ:PEPG) stock price recorded a 49.89% decrease, falling to $2.12. The stock is trading 35.22% lower than a month ago. |
| ITRM | -37.36% | ITERUM THERAPEUTICS PLC's (NASDAQ:ITRM) shares fell 37.36% to $0.04 during Tuesday's pre-market session. After experiencing a 97.75% increase in yesterday's session, ITRM is showing a reversal in today's pre-market session with a 37.36% decrease. |
| CDT | -28.34% | Tuesday's pre-market session showed a 28.34% decrease in the stock price of CDT EQUITY INC (NASDAQ:CDT), reaching $6.7. After yesterdays gain of 19.11%, it goes down with 28.34% in today's pre-market session. |
| PMNT | -27.78% | Tuesday's pre-market session showed a 27.78% decrease in the stock price of PERFECT MOMENT LTD (NYSEARCA:PMNT), reaching $0.23. After experiencing a 74.73% increase in yesterday's session, PMNT is showing a reversal in today's pre-market session with a 27.78% decrease. Yesterday the company had a press release: Perfect Moment Secures $12 Million in Growth Financing to Support Path to Profitability and Accelerated Growth. |
| PHR | -25.5% | PHREESIA INC's (NYSE:PHR) stock price decreased by 25.5% to $8.5. A press release (Phreesia Announces Fourth Quarter Fiscal 2026 Results) was released yesterday. |
| NDRA | -23.07% | During Tuesday's pre-market session, the shares of ENDRA LIFE SCIENCES INC (NASDAQ:NDRA) declined by 23.07%, reaching $3.6. In the last year the stock gained 32.2%. |
| PSTV | -22.32% | The stock price of PLUS THERAPEUTICS INC (NASDAQ:PSTV) is declining by 22.32%, reaching $0.17 during Tuesday's pre-market session. In the last month the share price dropped with 28.37%. |
| HUBC | -21.49% | HUB CYBER SECURITY LTD's (NASDAQ:HUBC) stock price is declining with 21.49% to a price of $0.1. In the last month the share price dropped with 90.62%. |
| SVC | -20.11% | The stock price of SERVICE PROPERTIES TRUST (NASDAQ:SVC) is declining by 20.11%, reaching $1.43 during Tuesday's pre-market session. Yesterday the company had a press release: Service Properties Trust Announces $500 Million Underwritten Public Offering of Common Shares. |
| INM | -20.05% | INMED PHARMACEUTICALS INC's (NASDAQ:INM) stock price recorded a 20.05% decrease, falling to $0.49. The stock is trading 25.0% lower than a month ago. |
For the full premarket loser list go to our premarket losers page.